Spotlight on Gene Therapy: finding a Cure

Chris Mueller will present our work on a novel humanized liver mouse model in an oral presentation entitled "Selective Advantage of Hepatocytes Expressing Wild-Type Alpha-1 Antitrypsin (AAT) in a Novel Human Liver Xenograft Model: A Model for Correction of a Gain-Of-Function Mutation" at the American Society of Gene and Cell Therapy 2015 Annual Meeting, on May 13-16 in New Orleans, Louisiana.

Our lab will also present three posters:

• Chris Mueller will present "Simultaneous Disruption of Five SerpinA1 Genes in Mice Using CRISPR/Cas9 to Generate the First Animal Model of Alpha-1 Antitrypsin Deficiency".
• Gwladys Gernoux will present "Detection and Characterization of Immune Response Against AAVrh10 Vector After Intrathecal Vector Delivery in Non-Human Primates".
• Florie Borel will present "Developing Strategies To Improve the Current Clinical Vector AAV1-CB-AAT for Alpha-One Antitrypsin Deficiency".