USMLE | Skin & Subcutaneous Tissue

Normal Processes

Embryonic development, fetal maturation, and neonatal changes

Organ structure and function, including barrier function, thermal regulation

Cell/tissue structure and function, eccrine function

Repair, regeneration, and changes associated with stage of life (eg, senile purpura, male pattern baldness, postmenopausal hair changes)

Skin defense mechanisms and normal flora

Abnormal Processes: Health and Health Maintenance, Screening, Diagnosis, Management, Risks, Prognosis

Infectious, immunologic, and inflammatory disorders

• • infectious disorders and infestations
    • bacterial: cellulitis, erysipelas, impetigo, staphylococcal scalded skin syndrome;
      • abscess, cutaneous, including septic abscess; anthrax (Bacillus anthracis); carbuncle; folliculitis; pilonidal cyst, infected; pyoderma gangrenosum; MSSA and MRSA skin infections; mycobacterial infections (eg, leprosy, draining sinus); scarlet fever (group A streptococcus)
    • viral: herpes simplex type 1 & type 2, herpes zoster, Ramsay-Hunt syndrome; molluscum contagiosum; hand-foot-and-mouth disease; herpangina; parvovirus; chickenpox, erythema infectiosum (fifth disease), rubella, measles, roseola (exanthema subitum); verrucae vulgaris
    • fungal (deep and superficial): candidiasis, skin; dermatophytosis, tinea corporis;
      • dermatomycoses; diaper rash; onychomycosis
    • parasitic: cutaneous larva migrans; cutaneous leishmaniasis
    • infestations, nonvenomous bites, stings: scabies; lice; insect bites, including bed bugs
  • immunologic and inflammatory disorders
    • papulosquamous and eczematous dermatoses: psoriasis; lichen planus and lichenoid dermatoses; allergic/irritant contact dermatitis (eg, nickel); dermatoses caused by plants (poison ivy, poison oak)
    • vesiculobullous disorders: epidermolysis bullosa; dermatitis herpetiformis; pemphigus; pemphigoid
    • urticaria, erythema, exanthema, and purpura: erythema nodosum; atopic dermatitis; pityriasis rosea; urticaria; Stevens-Johnson syndrome, erythema multiforme, toxic epidermal necrolysis
    • autoimmune disorders: vitiligo

Neoplasms

• • benign neoplasms, cysts and other skin lesions: actinic keratoses; cysts, including epidermal; hemangiomas; lipoma; pigmented nevi; seborrheic keratosis; xanthomas
  • malignant neoplasms: basal cell carcinoma; squamous cell carcinoma; melanoma, including genital; Kaposi sarcoma; cutaneous T-cell lymphoma, mycosis fungoides

Adnexal disorders (hair and hair follicles, nails, sweat glands, sebaceous glands, oral mucous membranes)

• • disorders of the hair and hair follicles: alopecia; seborrhea capitis/seborrheic dermatitis; tinea barbae and capitis
  • disorders of the nails (including ingrowing nail)
  • disorders of sweat and sebaceous glands: acne vulgaris; hidradenitis suppurativa; hyperhidrosis; ichthyosis; rosacea

Oral disease: aphthous ulcers (stomatitis, canker sores); leukoplakia

Disorders of pigmentation: albinism; lentigo

Traumatic and mechanical disorders: animal bites (dogs, cats, etc); burns or wounds affecting the skin or subcutaneous tissue (eg, sunburn, other including blast injuries and burns); cauliflower ear; effects of ultraviolet light; keloids; tattoo; thermal injury, perniosis, frostbite; ulcers, decubitus

Congenital disorders: xeroderma pigmentosum; benign lesions in neonates, infants, children (eg, congenital nevi)

Adverse effects of drugs on skin and subcutaneous tissue: drug reactions, eruptions, including local reaction to vaccine

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