Metabolism Core

Osmotic pumps or subcutaneous injection for drug trial study

Mini-osmotic pump will be subcutaneously implanted for chronic delivery of drugs. For this, mice will be anesthetized with ketamine/xylazine, and osmotic pumps containing drug or placebo will be subcutaneously inserted to the mice prior to the metabolic experiments. Alternatively, drug or placebo may be administered using subcutaneous injection or oral gavage.