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Recent Publications

(From 2017-Present Only)

  1. Stojcevski M, Cheung A, Agwu V, Fan X. Exploring Zentangle as a virtual mindfulness-based art therapy for people with serious mental illness. Frontiers in Psychiatry, 2023; doi: 10.3389/fpsyt.2023.1260937. PMID: 38098622.

  2. Cui Z, Yuan Y, Cheung A, Yu T, Hu K, Wang C, Fan X. Acculturation and mental health help-seeking behavior in a community cohort of individuals of Chinese descent. Asian journal of Psychiatry, 2023; https://doi.org/10.1016/j.ajp.2023.103628. PMID: 37201382.

  3. Wang Z, Yuan X, Zhu Z, Pang L, Ding S, Li X, Kang Y, Hei G, Zhang L, Zhang X, Wang S, Jian X, Li Z, Zheng C, Fan X, Hu S, Shi Y, Song X. Multiomics analyses reveal microbiome-gut-brain crosstalk centered on aberrant gamma-aminobutyric acid and tryptophan metabolism in drug-naïve patients with first-episode schizophrenia. Schizophrenia Bulletin, 2023; doi: 10.1093/schbul/sbad026. PMID: 37119525.

  4. Cheung A, Dutta P, Kovic Y, Stojcevski M, Fan X. Food4Thought: a medical trainee led, remotely delivered nutrition outreach program for individuals with serious mental illness. Academic Psychiatry, 2023; 47, 406-410. PMID: 36447069.

  5. Yuan X, Li X, Kang Y, Pang L, He G, Zhang X, Wang S, Zhao X, Zhang S, Tao Q, Zhang L, Zhu Q, Lv L, Fan X, Hu S, Song X. Gut mycobiota dysbiosis in drug-naïve, first episode schizophrenia. Schizophrenia Research, 2022; 250, 76-86. PMID: 36370535.
  6. Harrington A, Fan X. Methamphetamine-associated psychosis: what should clinicians know? Psychiatric Times, 2022; 39(7).
  7. Li X, Yuan X, Pang L, Zhang S, Li Y, Huang X, Fan X, Song X. The effect of serum lipids and short-chani fatty acids on cognitive function in drug-naïve, first episode schizophrenia patients. Psychiatry Research, 2022; doi: 10.1016/j.psychres.2022.114582. PMID: 35526421
  8. Cheung A, Agwu V, Stojcevski M, Wood L, Fan X. A pilot remote drama therapy program using the co-active therapeutic theater model with people with serious mental illness. Community Mental Health Journal, 2022; doi: 10.1007/s10597-022-00977-z. PMID: 35583837.
  9. Li M, Qiu Y, Zhang J, Liu Y, Zhao Y, Ja Q, Fan X, Li J. Improvement of adjunctive berberine treatment on negative symptoms in patients with schizophrenia. European Archives of Psychiatry and Clinical Neuroscience, in press.
  10. Chen S, Tang Y, Fan X, Qiao Y, Wang J, Wen H, Wang W, Wang H, Yang F, Sheng J. The role of white matter abnormality in the left anterior corona radiata: in relation to formal thought disorder in patients with schizophrenia. Psychiatry Research, 2022; doi: 10.1016/j.psychres.2021.114302. PMID: 34890908.
  11. Wang J, Hart K, Qi W, Ardekani B, Marx J, Freudenreich O, Cather C, Holt D, Bello I, Diminich E, Tang Y, Worthington M, Zeng B, Wu R, Fan X, Zhao J, Wang J, Goff DC. Association of aripiprazole with reduced hippocampal atrophy during maintenance treatment of first-episode schizophrenia. Journal of Clinical Psychopharmacology, 2021; 41, 244-249. PMID: 33814546.
  12. Li X, Fan X, Yuan X, Pang L, Hu S, Wang Y, Huang X, Song X. The role of butyric acid in treatment response in drug-naïve first episode schizophrenia. Frontiers in Psychiatry, 2021; doi: 10.3389/fpsyt.2021.724664. eCollection 2021. PMID: 34497548.
  13. Qi W, Blessing E, Ardekani B, Li C, Hart K, Freudenreich F, Cather C, Holt D, Bello I, Diminich E, Tang Y, Worthington M, Zeng B, Wu R, Fan X, Troxel A, Zhao J, Wang J, Goff DC. Effect of citalopram on hippocampal atrophy in first-episode schizophrenia: structural MRI results from the DECIFER trial. Psychiatry Research Neuroimaging, in press. PMID: 33857750.
  14. Yuan X, Wang Y, Li X, Jiang J, Kang Y, Pang L, Zhang P, Li A, Lv L, Andreassen O, Fan X, Hu S, Song X. Gut microbial biomarkers for the treatment response in first episode, drug-free schizophrenia: a 24-week follow-up study. Translational Psychiatry, 2021; doi: 10.1038/s41398-021-01531-3. PMID: 34376634.
  15. Cheung A, Selland J, Hamada K, Chiang M, Fan X. Walking together: exploring perspectives, attitudes, and barriers on nutrition and exercise among individuals with serious mental illness. Current Psychology, in press.
  16. Fattahi C, Hamada K, Kosuru S, Polavarapu M, Chiang M, Sitthichai R, Fan X*. Mindfulness-based therapy for schizophrenia. Psychiatry Research, 2021; doi: 10.1016/j.psychres.2021.113707. PMID: 33421838.
  17. Li X, Guo X, Fan X, Feng T, Wang C, Yao Z, Xu X, Chen Z, Wang H, Xie S, He J, Zhuo K, Xiang Q, Wang J, Smith B, Jin H, Keshavan M, Marder S, Davis J, Jiang K, Xu Y. Sequential multiple-assignment randomized trials to compare antipsychotic treatments (SMART-CAT) in first-episode schizophrenia patients: rationale and trial design, Schizophrenia Research, 2021; 230, 87-94. PMID: 33279374.
  18. Cheung A, Reid-Varley W, Chiang M, Villemejane M, Wood L, Butler J, Fan X. Dual diagnosis theatre: a pilot drama therapy study for individuals with serious mental illness and co-occurring substance use disorder. Schizophrenia Research, 2021; 230, 95-97. PMID: 33191082.
  19. Tao Q, Yang Y, Li H, Yuan X, Miao Y, Huang X, Wang Y, Andreassen O, Fan X, Song X. Insulin resistance and oxidative stress: in relation to cognitive function and psychopathology in drug-naïve, first-episode schizophrenia. Frontiers in Psychiatry, 2020; doi: 10.3389/fpsyt.2020.537280. PMID: 33329081.
  20. Li W, Yang Y, Zhang L, Liu Q, Shao M, Zhang Y, Ding M, Lu Y, Yu H, Fan X, Song M, Lv L. Solute carrier family 1 (SLC1A1) contributes to susceptibility and psychopathology symptoms of schizophrenia in the Han Chinese population. Frontiers in Psychiatry, 2020; doi: 10.3389/fpsyt.2020.559210. PMID: 33173509.
  21. Hamada K, Fan X*. Invited commentary: The impact of COVID-19 on individuals living with serious mental illness, Schizophrenia Research, 2020, doi:10.1016/j.schres.2020.05.054. PMID: 32473931
  22. Yang Y, Zhang L, Guo D, Zhang L, Yu H, Liu Q, Su X, Shao M, Song M, Zhang Y, Ding M, Lu Y, Liu B, Li W, Yue W, Fan X, Yang G, Lv L. Association of DTNBP1 with Schizophrenia: Findings from two Independent samples of Han Chinese population. Frontiers Psychiatry, 2020, doi.org/10.3389/fpsyt.2020.00446. PMID: 32581860. 
  23. Oh S, Fan X. The role of nitric oxide in schizophrenia: current understanding and therapeutic implications. Schizophrenia Research, 2020, doi:10.1016/j.schres.2020.05.050. PMID: 3247562.
  24. Worthington M, Petkova E, Freudenreich O, Cather C, Holt D, Bello I, Diminich E, Tang Y, Ardekani B, Zeng B, Wu R, Fan X, Zhao J, Wang J, Goff DC. Air pollution and hippocampal atrophy in first episode schizophrenia. Schizophrenia Research, 2020, 10.1016/j.schres.2020.03.001. PMID: 32169403.
  25. Wei Q, Zhao L, Zou Y, Wang J, Qiu Y, Niu M, Kang Z, Liu X, Tang Y, Li C, Zhang J, Fan X, Huang R, Han Z. The role of altered brain structural connectivity in resilience, vulnerability, and disease expression to schizophrenia. Progress in Neuropsychopharmacology and Biological Psychiatry, 2020, doi: 10.1016/j.pnpbp.2020.109917. PMID: 32169560.
  26. Cheung A, Polavarapu M, Kosuru S, Chiang M, Lombardi D, Liu M, Bakeman D, Raj A, Skehan B, Fan X. Treatment and services for psychosis: are college campuses a novel frontier for early detection and intervention? Psychiatry Research, 2020, 10.1016/j.psychres.2019.112699. PMID: 31813595.
  27. Li H, Ou Y, Liu F, Chen J, Zhao J, Guo W, Fan X*. Reduced connectivity in anterior cingulate cortex as an early predictor to treatment response in drug-naïve, first episode schizophrenia: a global-brain functional connectivity analysis. Schizophrenia Research, 2020, doi: 10.1016/j.schres.2019.09.003. PMID: 31522869.
  28. Wei Q, Yao Y, Qiu Y, Cui J, Li L, Zhang J, Guan N, Fan X. Research training as part of psychiatry residency training in North America: implications for psychiatry residency training in China. Chinese Journal of Medical Education, 2020, http://caod.oriprobe.com/articles/58502912/The_practice_and_enlightenment_of_research_ability.htm.
  29. Zhang L, Bao J, Harrington A, Fan X, Ning Z, Zhang J, Hu M, Zhou Z, Cai Z, Zhao M, Du J. Mixed methods to explore factors associated with the decline of patients in the Methadone Maintenance Treatment program in Shanghai, China. Harm Reduction Journal, 2019; 16(1):34. doi: 10.1186/s12954-019-0304-8. PMID: 31133016.
  30. Li H, Guo W, Liu F, Cheng J, Su Q, Zhang Z, Fan X, Zhao J. Enhanced baseline activity in the left ventromedial putamen predicts individual treatment response in drug-naïve, first episode schizophrenia: results from two independent study samples. EBioMedicine, 2019; 46, 248-255. PMID: 31307956.
  31. Chiang M, Du J, Lombardi D, Harrington A, Shukair N, Zhao M, Fan X. Methamphetamine-associated psychosis: clinical presentation, biological basis and treatment options. Human Psychopharmacology: Clinical and Experimental, 2019, 10.1002/hup.2710. PMID: 31441135.
  32. Wu R, Ou Y, Liu F, Chen J, Li H, Zhao J., Fan X. Reduced brain activity in the right putamen as an early predictor for treatment response in drug-naïve, first episode schizophrenia. Frontiers in Psychiatry, 2020, doi: 10.3389/fpsyt.2019.00741. PMID: 31649567.
  33. Oh S, Fan X*. Role of the angiotensin system in the pathophysiology of schizophrenia: implications for pharmacotherapy. CNS Drugs, 2019; 33, 539-547. PMID: 30993607.
  34. Chiang M, Reid-Varley WB, Fan X. Creative art therapy for mental illness. Psychiatry Research, 2019; 275, 129-136. PMID: 30901671.
  35. Zhuo K, Tang Y, Song Z, Wang Y, Wang J, Qian Z, Li H, Mei L, Zhu D, Xiang Q, Chen T, Yang Z, Xu Y, Fan X, Wang J, Liu D. Repetitive transcranial magnetic stimulation as an adjunctive treatment for negative symptoms and cognitive impairment in patients with schizophrenia: a randomized, double-blind, sham-controlled trial. Neuropsychiatric Disease and Treatment, 2019; 15, 1141-1150. PMID: 31190822.
  36. Liu Y, Zhao J, Fan X, Guo W. Dysfunction in serotonergic and noradrenergic systems and somatic symptoms in psychiatric disorders. Frontiers in Psychiatry, 2019; 10:286.doi: 10.3389/fpsyt.2019.00286. PMID: 31178761.
  37. Robertson I, Cheung A, Fan X. Insomnia in patients with schizophrenia: current understanding and treatment options. Progress in Neuropsychopharmacology and Biological Psychiatry, 2019; 92, 235-242. PMID: 30707986.
  38. Wu C, Chiang M, Fusaro-Davis M, Cimpeanu C, Harrington A, Fan X. Lifestyle education for patients with severe mental illness during their psychiatric inpatient stay. Asian Journal of Psychiatry, 2019; 40, 15-17. PMID: 30673623.
  39. Fan X, Copeland P, Shukair N, Harrington A, Freudenreich O, Goff D, Henderson D. Adjunctive telmisartan treatment on body metabolism in clozapine or olanzapine treated patients with schizophrenia: a randomized, double blind, placebo-controlled trial. Psychopharmacology (Berlin), 2019, 236, 1949-1957. PMID: 30747254.
  40. Brown H, Freudenreich O, Fan X, Heard S, Goff D, Petrides G, Harrington A, Kane JM, Judge H, Hoeppner B, Fava M, Perlis RH. Intravenous sodium nitroprusside treatment for outpatients with schizophrenia: a randomized clinical trial. JAMA Psychiatry, 2019; 76, 691-699. PMID: 30916714.
  41. Goff D, Freudenreich O, Cather C, Holt D, Bello I, Diminich E, Tang Y, Ardekani B, Worthington M, Zeng B, Wu R, Fan X, Li C, Troxel A, Wang J, Zhao J. Citalopram in first episode schizophrenia: the DECIFER trial. Schizophrenia Research, 2019; 208, 331-337. PMID: 30709746.
  42. Li X, Tian X, Lv L, Hei G, Huang X, Fan X, Zhang J, Zhang J, Pang L, Song X. Microglia activation in the offspring of prenatal Poly I:C exposed rats: a PET imaging and immunohistochemistry study. General Psychiatry, 2018; 31(1):e000006. doi: 10.1136/gpsych-2018-000006. PMID: 30582116.
  43. Guo W, Liu F, Cheng J, Su Q, Zhang Z, Li H, Zhu F, Fan X, Zhao J. Disrupted asymmetry of inter- and intra-hemispheric functional connectivity in patients with drug-naive, first-episode schizophrenia and their unaffected siblings. EBioMedicine, 2018; pii: S2352-3964(18)30370-0. PMID: 30241918.
  44. Yuan X, Zhang P, Wang, Y, Liu Y, Li X, Kumar B, Hei G, Lv L, Huang X, Fan X, Song X. Changes in metabolism and microbiota after 24-week risperidone treatment in drug naïve, normal weight patients with first episode schizophrenia. Schizophrenia Research, 2018; 201, 299-306. PMID: 29859859.
  45. Wu C, Chiang M, Harrington A, Kim S, Ziedonis D, Fan X. Racial Disparity in Mental Disorder Diagnosis and Treatment between Non-Hispanic White and Asian American Patients in a General Hospital. Asian Journal of Psychiatry, 2018; 34, 78-83. PMID: 29674132.
  46. Liu F, Lv H, Ye Q, Xu X, Fan X, Zhao J. A comprehensive treatment approach for first episode schizophrenia: Introduction and adaptation of the NAVIGATE model in China. Chinese Journal of Psychiatry, 2018; 51, 273-277.
  47. Liu F, Zhang B, Xie L, Ruan Y, Xu X, Zeng Y, Messina L, Zhang J, Fan X. Changes in plasma levels of nitric oxide metabolites and negative symptoms after 16-week minocycline treatment in patients with schizophrenia. Schizophrenia Research, 2018; 199, 390-394. PMID: 29526457.
  48. Goff D, Zeng B, Ardekani B, Diminich E, Tang Y, Fan X, Galatzer-Levy I, Li C, Troxel A, Wang J. Association of hippocampal atrophy with duration of untreated psychosis and molecular biomarkers during initial antipsychotic treatment of first episode psychosis. JAMA Psychiatry, 2018; 75, 370-378. PMID: 29466532.
  49. Luo Y, Liu F, Natarajan R, Shukair N, Copeland P, Fan X. Salsalate as an adjunctive treatment for psychopathology and cognition in patients with schizophrenia: a proof of concept study. International Clinical Psychopharmacology, 2018; 33, 88-91. PMID: 29084087.
  50. Liu F, Xie L, Zhang B, Ruan Y, Zeng Y, Xu X, Zhao J, Fan X. No effect of adjunctive minocycline treatment on body metabolism in patients with schizophrenia. Journal of Clinical Psychopharmacology, 2018; 38, 125-128. PMID: 29424804.
  51. Lyu X, Du J, Zhan, G, Wu Y, Su H, Zhu Y, Jarskog F, Zhao M, Fan X. Naltrexone and bupropion combination treatment for smoking cessation and weight loss in patients with schizophrenia. Frontiers in Pharmacology, 2018; 9:181. doi: 10.3389/fphar. PMID: 29563871.
  52. Ruan X, Zhong N, Yang Z, Fan X, Zhuang W, Du J, Jiang H, Zhao M. Gray matter volume showed dynamic alterations in methamphetamine users at 6 and 12 months abstinence: a longitudinal voxel-based morphometry study. Progress in Neuropsychopharmacology and Biological Psychiatry, 2018; 81, 350-355. PMID: 28887180.
  53. Wang S, Zhang Y, Lv L, Wu, R, Fan X, Zhao J, Guo W. Abnormal regional homogeneity as a potential imaging biomarker for adolescent-onset schizophrenia: a resting-state fMRI study and support vector machine analysis. Schizophrenia Research, 2018; 192, 179-184. PMID: 28587813.
  54. Fan X, Song X, Jarskog, F, Natarajan R, Shukair N, Freudenreich O, Henderson D, Goff D. The effect of adjunctive telmisartan treatment on psychopathology and cognition in patients with schizophrenia. Acta Psychiatrica Scandinavica, 2017; 136, 465-472. PMID: 28851055.
  55. Mitra S, Natarajan R, Ziedonis D, Fan X. Antioxidant and anti-inflammatory nutrient status, supplementation, and mechanisms in patients with schizophrenia. Progress in Neuropsychopharmacology and Biological Psychiatry, 2017; 78, 1-11. PMID: 28499901
  56. Zhao Z, Huang T, Tang C, Ni K, Pan X, Yan C, Fan X, Xu D, Luo Y. Altered Resting-State Intra- and Inter- Network Functional Connectivity in Patients with Persistent Somatoform Pain Disorder. PLoS One, 2017; 12(4):e0176494. doi: 10.1371/journal.pone.0176494. PMID:28453543.
  57. Wang Y, Tang W, Fan X, Zhang J, Geng D, Jiang K, Zhu D, Song Z, Xiao Z, Liu D. Resting-state functional connectivity changes within the default mode network and the salience antipsychotic treatment in early-phase schizophrenia. Neuropsychiatric Disease and Treatment, 2017. 13:397-406. doi:10.2147/NDT. S123598. PMID: 28223812.
  58. Pang L, Kennedy D, Wei Q, Lv L, Gao J, Li H, Quan M, Li X, Yang Y, Fan X, Song X. Decreased functional connectivity of insular cortex in drug naïve first episode schizophrenia: in relation to symptom severity. PLoS One, 2017; 12(1):e0167242. doi: 10.1371/journal.pone.0167242. PMID: 28107346.
  59. Liu D, Ji C, Zhuo K, Song Z, Wang Y, Mei L, Zhu D, Xiang Q, Chen T, Yang Z, Zhu G, Wang Y, Cheung E, Xiang Y, Fan X, Chan R, Xu Y, Jiang K. Impaired cue identification and intention retrieval underlie prospective memory deficits in patients with first-episode schizophrenia. Australia and New Zealand Journal of Psychiatry, 2017; 51, 270-277. PMID: 27004487.