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Total: displaying 10 out of 100 results
  • Protein Citrullination in Amyotrophic Lateral Sclerosis and Other Neurodegenerative Diseases

    Monday, December 23, 2024
    Author(s): Issa O Yusuf,Webb Camille,Paul R Thompson,Zuoshang Xu
    Source: Journal of experimental neurology
  • Genomic analysis of intracranial and subcortical brain volumes yields polygenic scores accounting for variation across ancestries

    Monday, October 21, 2024
    Author(s): Luis M García-Marín,Adrian I Campos,Santiago Diaz-Torres,Jill A Rabinowitz,Zuriel Ceja,Brittany L Mitchell,Katrina L Grasby,Jackson G Thorp,Ingrid Agartz,Saud Alhusaini,David Ames,Philippe Amouyel,Ole A Andreassen,Konstantinos Arfanakis,Alejandro Arias-Vasquez,Nicola J Armstrong,Lavinia Athanasiu,Mark E Bastin,Alexa S Beiser,David A Bennett,Joshua C Bis,Marco P M Boks,Dorret I Boomsma,Henry Brodaty,Rachel M Brouwer,Jan K Buitelaar,Ralph Burkhardt,Wiepke Cahn,Vince D Calhoun,Owen T Carmichael,Mallar Chakravarty,Qiang Chen,Christopher R K Ching,Sven Cichon,Benedicto Crespo-Facorro,Fabrice Crivello,Anders M Dale,George Davey Smith,Eco J C de Geus,Philip L De Jager,Greig I de Zubicaray,Stéphanie Debette,Charles DeCarli,Chantal Depondt,Sylvane Desrivières,Srdjan Djurovic,Stefan Ehrlich,Susanne Erk,Thomas Espeseth,Guillén Fernández,Irina Filippi,Simon E Fisher,Debra A Fleischman,Evan Fletcher,Myriam Fornage,Andreas J Forstner,Clyde Francks,Barbara Franke,Tian Ge,Aaron L Goldman,Hans J Grabe,Robert C Green,Oliver Grimm,Nynke A Groenewold,Oliver Gruber,Vilmundur Gudnason,Asta K Håberg,Unn K Haukvik,Andreas Heinz,Derrek P Hibar,Saima Hilal,Jayandra J Himali,Beng-Choon Ho,David F Hoehn,Pieter J Hoekstra,Edith Hofer,Wolfgang Hoffmann,Avram J Holmes,Georg Homuth,Norbert Hosten,M Kamran Ikram,Jonathan C Ipser,Clifford R Jack,Neda Jahanshad,Erik G Jönsson,Rene S Kahn,Ryota Kanai,Marieke Klein,Maria J Knol,Lenore J Launer,Stephen M Lawrie,Stephanie Le Hellard,Phil H Lee,Hervé Lemaître,Shuo Li,David C M Liewald,Honghuang Lin,W T Longstreth,Oscar L Lopez,Michelle Luciano,Pauline Maillard,Andre F Marquand,Nicholas G Martin,Jean-Luc Martinot,Karen A Mather,Venkata S Mattay,Katie L McMahon,Patrizia Mecocci,Ingrid Melle,Andreas Meyer-Lindenberg,Nazanin Mirza-Schreiber,Yuri Milaneschi,Thomas H Mosley,Thomas W Mühleisen,Bertram Müller-Myhsok,Susana Muñoz Maniega,Matthias Nauck,Kwangsik Nho,Wiro J Niessen,Markus M Nöthen,Paul A Nyquist,Jaap Oosterlaan,Massimo Pandolfo,Tomas Paus,Zdenka Pausova,Brenda W J H Penninx,G Bruce Pike,Bruce M Psaty,Benno Pütz,Simone Reppermund,Marcella D Rietschel,Shannon L Risacher,Nina Romanczuk-Seiferth,Rafael Romero-Garcia,Gennady V Roshchupkin,Jerome I Rotter,Perminder S Sachdev,Philipp G Sämann,Arvin Saremi,Muralidharan Sargurupremraj,Andrew J Saykin,Lianne Schmaal,Helena Schmidt,Reinhold Schmidt,Peter R Schofield,Markus Scholz,Gunter Schumann,Emanuel Schwarz,Li Shen,Jean Shin,Sanjay M Sisodiya,Albert V Smith,Jordan W Smoller,Hilkka S Soininen,Vidar M Steen,Dan J Stein,Jason L Stein,Sophia I Thomopoulos,Arthur W Toga,Diana Tordesillas-Gutiérrez,Julian N Trollor,Maria C Valdes-Hernandez,Dennis van T Ent,Hans van Bokhoven,Dennis van der Meer,Nic J A van der Wee,Javier Vázquez-Bourgon,Dick J Veltman,Meike W Vernooij,Arno Villringer,Louis N Vinke,Henry Völzke,Henrik Walter,Joanna M Wardlaw,Daniel R Weinberger,Michael W Weiner,Wei Wen,Lars T Westlye,Eric Westman,Tonya White,A Veronica Witte,Christiane Wolf,Jingyun Yang,Marcel P Zwiers,M Arfan Ikram,Sudha Seshadri,Paul M Thompson,Claudia L Satizabal,Sarah E Medland,Miguel E Rentería
    Source: Nature genetics
  • AFM41a: A Novel PAD2 Inhibitor for Sepsis Treatment-Efficacy and Mechanism

    Monday, October 21, 2024
    Author(s): Tao Dong,Leonard Barasa,Xin Yu,Wenlu Ouyang,Liujiazi Shao,Chao Quan,Su He Wang,Jifeng Zhang,Morgan Salmon,Allan Tsung,Hasan B Alam,Jianjie Ma,Paul R Thompson,Yongqing Li
    Source: International journal of biological sciences
  • Genomic analysis of intracranial and subcortical brain volumes yields polygenic scores accounting for variation across ancestries

    Monday, October 07, 2024
    Author(s): Luis M García-Marín,Adrian I Campos,Santiago Diaz-Torres,Jill A Rabinowitz,Zuriel Ceja,Brittany L Mitchell,Katrina L Grasby,Jackson G Thorp,Ingrid Agartz,Saud Alhusaini,David Ames,Philippe Amouyel,Ole A Andreassen,Konstantinos Arfanakis,Alejandro Arias Vasquez,Nicola J Armstrong,Lavinia Athanasiu,Mark E Bastin,Alexa S Beiser,David A Bennett,Joshua C Bis,Marco Pm Boks,Dorret I Boomsma,Henry Brodaty,Rachel M Brouwer,Jan K Buitelaar,Ralph Burkhardt,Wiepke Cahn,Vince D Calhoun,Owen T Carmichael,Mallar Chakravarty,Qiang Chen,Christopher R K Ching,Sven Cichon,Benedicto Crespo-Facorro,Fabrice Crivello,Anders M Dale,George Davey Smith,Eco Jc de Geus,Philip L De Jager,Greig I de Zubicaray,Stéphanie Debette,Charles DeCarli,Chantal Depondt,Sylvane Desrivières,Srdjan Djurovic,Stefan Ehrlich,Susanne Erk,Thomas Espeseth,Guillén Fernández,Irina Filippi,Simon E Fisher,Debra A Fleischman,Evan Fletcher,Myriam Fornage,Andreas J Forstner,Clyde Francks,Barbara Franke,Tian Ge,Aaron L Goldman,Hans J Grabe,Robert C Green,Oliver Grimm,Nynke A Groenewold,Oliver Gruber,Vilmundur Gudnason,Asta K Håberg,Unn K Haukvik,Andreas Heinz,Derrek P Hibar,Saima Hilal,Jayandra J Himali,Beng-Choon Ho,David F Hoehn,Pieter J Hoekstra,Edith Hofer,Wolfgang Hoffmann,Avram J Holmes,Georg Homuth,Norbert Hosten,M Kamran Ikram,Jonathan C Ipser,Clifford R Jack,Neda Jahanshad,Erik G Jönsson,Rene S Kahn,Ryota Kanai,Marieke Klein,Maria J Knol,Lenore J Launer,Stephen M Lawrie,Stephanie Le Hellard,Phil H Lee,Hervé Lemaître,Shuo Li,David Cm Liewald,Honghuang Lin,W T Longstreth,Oscar L Lopez,Michelle Luciano,Pauline Maillard,Andre F Marquand,Nicholas G Martin,Jean-Luc Martinot,Karen A Mather,Venkata S Mattay,Katie L McMahon,Patrizia Mecocci,Ingrid Melle,Andreas Meyer-Lindenberg,Nazanin Mirza-Schreiber,Yuri Milaneschi,Thomas H Mosley,Thomas W Mühleisen,Bertram Müller-Myhsok,Susana Muñoz Maniega,Matthias Nauck,Kwangsik Nho,Wiro J Niessen,Markus M Nöthen,Paul A Nyquist,Jaap Oosterlaan,Massimo Pandolfo,Tomas Paus,Zdenka Pausova,Brenda Wjh Penninx,G Bruce Pike,Bruce M Psaty,Benno Pütz,Simone Reppermund,Marcella D Rietschel,Shannon L Risacher,Nina Romanczuk-Seiferth,Rafael Romero-Garcia,Gennady V Roshchupkin,Jerome I Rotter,Perminder S Sachdev,Philipp G Sämann,Arvin Saremi,Muralidharan Sargurupremraj,Andrew J Saykin,Lianne Schmaal,Helena Schmidt,Reinhold Schmidt,Peter R Schofield,Markus Scholz,Gunter Schumann,Emanuel Schwarz,Li Shen,Jean Shin,Sanjay M Sisodiya,Albert V Smith,Jordan W Smoller,Hilkka S Soininen,Vidar M Steen,Dan J Stein,Jason L Stein,Sophia I Thomopoulos,Arthur W Toga,Diana Tordesillas-Gutiérrez,Julian N Trollor,Maria C Valdes-Hernandez,Dennis van 't Ent,Hans van Bokhoven,Dennis van der Meer,Nic Ja van der Wee,Javier Vázquez-Bourgon,Dick J Veltman,Meike W Vernooij,Arno Villringer,Louis N Vinke,Henry Völzke,Henrik Walter,Joanna M Wardlaw,Daniel R Weinberger,Michael W Weiner,Wei Wen,Lars T Westlye,Eric Westman,Tonya White,A Veronica Witte,Christiane Wolf,Jingyun Yang,Marcel P Zwiers,M Arfan Ikram,Sudha Seshadri,Paul M Thompson,Claudia L Satizabal,Sarah E Medland,Miguel E Rentería
    Source: medRxiv : the preprint server for health sciences
  • Muscle-specific pyruvate kinase isoforms, PKM1 and PKM2, regulate mammalian SWI/SNF proteins and histone 3 phosphorylation during myoblast differentiation

    Wednesday, June 05, 2024
    Author(s): Monserrat Olea-Flores,Tapan Sharma,Odette Verdejo-Torres,Imaru DiBartolomeo,Paul R Thompson,Teresita Padilla-Benavides,Anthony N Imbalzano
    Source: FASEB journal : official publication of the Federation of American Societies for Experimental Biology
  • Muscle-Specific Pyruvate Kinase Isoforms, Pkm1 and Pkm2, Regulate Mammalian SWI/SNF Proteins and Histone 3 Phosphorylation During Myoblast Differentiation

    Monday, April 22, 2024
    Author(s): Monserrat Olea-Flores,Tapan Sharma,Odette Verdejo-Torres,Imaru DiBartolomeo,Paul R Thompson,Teresita Padilla-Benavides,Anthony N Imbalzano
    Source: bioRxiv : the preprint server for biology
  • Targeting the GPI transamidase subunit GPAA1 abrogates the CD24 immune checkpoint in ovarian cancer

    Thursday, April 04, 2024
    Author(s): Alok K Mishra,Tianyi Ye,Shahid Banday,Ritesh P Thakare,Chinh Tran-To Su,Ngoc N H Pham,Amjad Ali,Ankur Kulshreshtha,Shreya Roy Chowdhury,Tessa M Simone,Kai Hu,Lihua Julie Zhu,Birgit Eisenhaber,Sara K Deibler,Karl Simin,Paul R Thompson,Michelle A Kelliher,Frank Eisenhaber,Sunil K Malonia,Michael R Green
    Source: Cell reports
  • GnRH Induces Citrullination of the Cytoskeleton in Murine Gonadotrope Cells

    Thursday, March 28, 2024
    Author(s): Elizabeth B Quigley,Stanley B DeVore,Shaihla A Khan,Zachary M Geisterfer,Heather M Rothfuss,Ari O Sequoia,Paul R Thompson,Jesse C Gatlin,Brian D Cherrington,Amy M Navratil
    Source: International journal of molecular sciences
  • PAD2 dysregulation and aberrant protein citrullination feature prominently in reactive astrogliosis and myelin protein aggregation in sporadic ALS

    Monday, January 22, 2024
    Author(s): Issa O Yusuf,Sepideh Parsi,Lyle W Ostrow,Robert H Brown,Paul R Thompson,Zuoshang Xu
    Source: Neurobiology of disease
  • NET formation is a default epigenetic program controlled by PAD4 in apoptotic neutrophils

    Wednesday, December 20, 2023
    Author(s): Yanfang Peipei Zhu,Mary Speir,ZheHao Tan,Jamie Casey Lee,Cameron J Nowell,Alyce A Chen,Hajera Amatullah,Ari J Salinger,Carolyn J Huang,Gio Wu,Weiqi Peng,Kasra Askari,Eric Griffis,Majid Ghassemian,Jennifer Santini,Motti Gerlic,William B Kiosses,Sergio D Catz,Hal M Hoffman,Kimberly F Greco,Edie Weller,Paul R Thompson,Lai Ping Wong,Ruslan Sadreyev,Kate L Jeffrey,Ben A Croker
    Source: Science advances
  • Peptidylarginine deiminase 2 citrullinates MZB1 and promotes the secretion of IgM and IgA

    Thursday, December 14, 2023
    Author(s): Benjamin Geary,Bo Sun,Ronak R Tilvawala,Leonard Barasa,Konstantin Tsoyi,Ivan O Rosas,Paul R Thompson,I-Cheng Ho
    Source: Frontiers in immunology
  • Citrullination profile analysis reveals peptidylarginine deaminase 3 as an HSV-1 target to dampen the activity of candidate antiviral restriction factors

    Wednesday, December 06, 2023
    Author(s): Selina Pasquero,Francesca Gugliesi,Matteo Biolatti,Valentina Dell'Oste,Camilla Albano,Greta Bajetto,Gloria Griffante,Linda Trifirò,Bianca Brugo,Stefano Raviola,Davide Lacarbonara,Qiao Yang,Sen Sudeshna,Leonard Barasa,Hafeez Haniff,Paul R Thompson,Santo Landolfo,Marco De Andrea
    Source: PLoS pathogens
  • Inhibiting MEK1 R189 citrullination enhances the chemosensitivity of docetaxel to multiple tumour cells

    Sunday, October 01, 2023
    Author(s): Teng Xue,Shujia Fei,Jian Gu,Nan Li,Pengxue Zhang,Xiaoqiu Liu,Paul R Thompson,Xuesen Zhang
    Source: Philosophical transactions of the Royal Society of London. Series B, Biological sciences
  • Protein citrullination: inhibition, identification and insertion

    Sunday, October 01, 2023
    Author(s): Leonard Barasa,Paul R Thompson
    Source: Philosophical transactions of the Royal Society of London. Series B, Biological sciences
  • A phase transition reduces the threshold for nicotinamide mononucleotide-based activation of SARM1, an NAD(P) hydrolase, to physiologically relevant levels

    Sunday, September 24, 2023
    Author(s): Janneke Doedée Icso,Paul Ryan Thompson
    Source: The Journal of biological chemistry
  • Development of LB244, an Irreversible STING Antagonist

    Monday, September 11, 2023
    Author(s): Leonard Barasa,Sauradip Chaudhuri,Jeffrey Y Zhou,Zhaozhao Jiang,Shruti Choudhary,Robert Madison Green,Elenore Wiggin,Michael Cameron,Fiachra Humphries,Katherine A Fitzgerald,Paul R Thompson
    Source: Journal of the American Chemical Society
  • Targeting STING oligomerization with small-molecule inhibitors

    Monday, August 07, 2023
    Author(s): Fiachra Humphries,Liraz Shmuel-Galia,Zhaozhao Jiang,Jeffrey Y Zhou,Leonard Barasa,Santanu Mondal,Ruth Wilson,Nadia Sultana,Scott A Shaffer,Sze-Ling Ng,G Scott Pesiridis,Paul R Thompson,Katherine A Fitzgerald
    Source: Proceedings of the National Academy of Sciences of the United States of America
  • SARM1, an Enzyme Involved in Axon Degeneration, Catalyzes Multiple Activities through a Ternary Complex Mechanism

    Monday, June 12, 2023
    Author(s): Janneke D Icso,Leonard Barasa,Paul R Thompson
    Source: Biochemistry
  • Current insights into the role of citrullination in thrombosis

    Saturday, May 06, 2023
    Author(s): R Madison Green,Paul R Thompson
    Source: Current opinion in chemical biology
  • Dual Inhibitors of Main Protease (MPro) and Cathepsin L as Potent Antivirals against SARS-CoV2

    Thursday, November 10, 2022
    Author(s): Santanu Mondal,Yongzhi Chen,Gordon J Lockbaum,Sudeshna Sen,Sauradip Chaudhuri,Archie C Reyes,Jeong Min Lee,Arshia N Kaur,Nadia Sultana,Michael D Cameron,Scott A Shaffer,Celia A Schiffer,Katherine A Fitzgerald,Paul R Thompson
    Source: Journal of the American Chemical Society
  • Phomoxanthone A Targets ATP Synthase

    Friday, September 09, 2022
    Author(s): Rameez Ali,Sangram S Parelkar,Paul R Thompson,Susan Mitroka-Batsford,Siddartha Yerramilli,Suzanne F Scarlata,Katelyn S Mistretta,Jeannine M Coburn,Anita E Mattson
    Source: Chemistry (Weinheim an der Bergstrasse, Germany)
  • Protein citrullination marks myelin protein aggregation and disease progression in mouse ALS models

    Thursday, September 08, 2022
    Author(s): Issa O Yusuf,Tao Qiao,Sepideh Parsi,Ronak Tilvawala,Paul R Thompson,Zuoshang Xu
    Source: Acta neuropathologica communications
  • Carbamylation of Integrin α IIb β 3: The Mechanistic Link to Platelet Dysfunction in ESKD

    Monday, August 29, 2022
    Author(s): Veronika Binder,Barbara Chruścicka-Smaga,Brith Bergum,Stéphane Jaisson,Philippe Gillery,Joar Sivertsen,Tor Hervig,Marta Kaminska,Ronak Tilvawala,Venkatesh V Nemmara,Paul R Thompson,Jan Potempa,Hans-Peter Marti,Piotr Mydel
    Source: Journal of the American Society of Nephrology : JASN
  • The chemical biology of NAD+ regulation in axon degeneration

    Sunday, July 03, 2022
    Author(s): Janneke D Icso,Paul R Thompson
    Source: Current opinion in chemical biology
  • Proximity-Dependent Labeling of Cysteines

    Thursday, November 11, 2021
    Author(s): Sudeshna Sen,Nadia Sultana,Scott A Shaffer,Paul R Thompson
    Source: Journal of the American Chemical Society
  • Applicability of Small-Molecule Inhibitors in the Study of Peptidyl Arginine Deiminase 2 (PAD2) and PAD4

    Friday, November 05, 2021
    Author(s): María Teresa Martín Monreal,Alexandra Stripp Rebak,Laura Massarenti,Santanu Mondal,Ladislav Šenolt,Niels Ødum,Michael L Nielsen,Paul R Thompson,Claus H Nielsen,Dres Damgaard
    Source: Frontiers in immunology
  • Pan-3C Protease Inhibitor Rupintrivir Binds SARS-CoV-2 Main Protease in a Unique Binding Mode

    Friday, September 10, 2021
    Author(s): Gordon J Lockbaum,Mina Henes,Jeong Min Lee,Jennifer Timm,Ellen A Nalivaika,Paul R Thompson,Nese Kurt Yilmaz,Celia A Schiffer
    Source: Biochemistry
  • A meta-analysis of deep brain structural shape and asymmetry abnormalities in 2,833 individuals with schizophrenia compared with 3,929 healthy volunteers via the ENIGMA Consortium

    Thursday, September 09, 2021
    Author(s): Boris A Gutman,Theo G M van Erp,Kathryn Alpert,Christopher R K Ching,Dmitry Isaev,Anjani Ragothaman,Neda Jahanshad,Arvin Saremi,Artemis Zavaliangos-Petropulu,David C Glahn,Li Shen,Shan Cong,Dag Alnaes,Ole Andreas Andreassen,Nhat Trung Doan,Lars T Westlye,Peter Kochunov,Theodore D Satterthwaite,Daniel H Wolf,Alexander J Huang,Charles Kessler,Andrea Weideman,Dana Nguyen,Bryon A Mueller,Lawrence Faziola,Steven G Potkin,Adrian Preda,Daniel H Mathalon,Juan Bustillo,Vince Calhoun,Judith M Ford,Esther Walton,Stefan Ehrlich,Giuseppe Ducci,Nerisa Banaj,Fabrizio Piras,Federica Piras,Gianfranco Spalletta,Erick J Canales-Rodríguez,Paola Fuentes-Claramonte,Edith Pomarol-Clotet,Joaquim Radua,Raymond Salvador,Salvador Sarró,Erin W Dickie,Aristotle Voineskos,Diana Tordesillas-Gutiérrez,Benedicto Crespo-Facorro,Esther Setién-Suero,Jacqueline Mayoral van Son,Stefan Borgwardt,Fabienne Schönborn-Harrisberger,Derek Morris,Gary Donohoe,Laurena Holleran,Dara Cannon,Colm McDonald,Aiden Corvin,Michael Gill,Geraldo Busatto Filho,Pedro G P Rosa,Mauricio H Serpa,Marcus V Zanetti,Irina Lebedeva,Vasily Kaleda,Alexander Tomyshev,Tim Crow,Anthony James,Simon Cervenka,Carl M Sellgren,Helena Fatouros-Bergman,Ingrid Agartz,Fleur Howells,Dan J Stein,Henk Temmingh,Anne Uhlmann,Greig I de Zubicaray,Katie L McMahon,Margie Wright,Derin Cobia,John G Csernansky,Paul M Thompson,Jessica A Turner,Lei Wang
    Source: Human brain mapping
  • A Streamlined Data Analysis Pipeline for the Identification of Sites of Citrullination

    Tuesday, September 07, 2021
    Author(s): Aaron J Maurais,Ari J Salinger,Micaela Tobin,Scott A Shaffer,Eranthie Weerapana,Paul R Thompson
    Source: Biochemistry
  • The role of SERPIN citrullination in thrombosis

    Thursday, August 05, 2021
    Author(s): Ronak Tilvawala,Venkatesh V Nemmara,Archie C Reyes,Nicoletta Sorvillo,Ari J Salinger,Deya Cherpokova,Saeko Fukui,Sarah Gutch,Denisa Wagner,Paul R Thompson
    Source: Cell chemical biology
  • PAD2-mediated citrullination of Fibulin-5 promotes elastogenesis

    Sunday, July 18, 2021
    Author(s): Bo Sun,Beverly Tomita,Ari Salinger,Ronak R Tilvawala,Ling Li,Hana Hakami,Tao Liu,Konstantin Tsoyi,Ivan O Rosas,Dieter P Reinhardt,Paul R Thompson,I-Cheng Ho
    Source: Matrix biology : journal of the International Society for Matrix Biology
  • Progesterone stimulates histone citrullination to increase IGFBP1 expression in uterine cells

    Tuesday, May 25, 2021
    Author(s): Coleman H Young,Bryce Snow,Stanley B DeVore,Adithya Mohandass,Venkatesh V Nemmara,Paul R Thompson,Baskaran Thyagarajan,Amy M Navratil,Brian D Cherrington
    Source: Reproduction (Cambridge, England)
  • Structures of human peptidylarginine deiminase type III provide insights into substrate recognition and inhibitor design

    Monday, May 10, 2021
    Author(s): Kazumasa Funabashi,Mizuki Sawata,Anna Nagai,Megumi Akimoto,Ryutaro Mashimo,Hidenari Takahara,Kenji Kizawa,Paul R Thompson,Kenji Ite,Kenichi Kitanishi,Masaki Unno
    Source: Archives of biochemistry and biophysics
  • Synthesis and Anticancer Activity of Structure Simplified Naturally-Inspired Dimeric Chromenone Derivatives

    Thursday, April 08, 2021
    Author(s): Rameez Ali,Yong Guan,Alexandria N Leveille,Elizabeth Vaughn,Sangram Parelkar,Paul R Thompson,Anita E Mattson
    Source: European journal of organic chemistry
  • 1q21.1 distal copy number variants are associated with cerebral and cognitive alterations in humans

    Tuesday, March 23, 2021
    Author(s): Ida E Sønderby,Dennis van der Meer,Clara Moreau,Tobias Kaufmann,G Bragi Walters,Maria Ellegaard,Abdel Abdellaoui,David Ames,Katrin Amunts,Micael Andersson,Nicola J Armstrong,Manon Bernard,Nicholas B Blackburn,John Blangero,Dorret I Boomsma,Henry Brodaty,Rachel M Brouwer,Robin Bülow,Rune Bøen,Wiepke Cahn,Vince D Calhoun,Svenja Caspers,Christopher R K Ching,Sven Cichon,Simone Ciufolini,Benedicto Crespo-Facorro,Joanne E Curran,Anders M Dale,Shareefa Dalvie,Paola Dazzan,Eco J C de Geus,Greig I de Zubicaray,Sonja M C de Zwarte,Sylvane Desrivieres,Joanne L Doherty,Gary Donohoe,Bogdan Draganski,Stefan Ehrlich,Else Eising,Thomas Espeseth,Kim Fejgin,Simon E Fisher,Tormod Fladby,Oleksandr Frei,Vincent Frouin,Masaki Fukunaga,Thomas Gareau,Tian Ge,David C Glahn,Hans J Grabe,Nynke A Groenewold,Ómar Gústafsson,Jan Haavik,Asta K Haberg,Jeremy Hall,Ryota Hashimoto,Jayne Y Hehir-Kwa,Derrek P Hibar,Manon H J Hillegers,Per Hoffmann,Laurena Holleran,Avram J Holmes,Georg Homuth,Jouke-Jan Hottenga,Hilleke E Hulshoff Pol,Masashi Ikeda,Neda Jahanshad,Christiane Jockwitz,Stefan Johansson,Erik G Jönsson,Niklas R Jørgensen,Masataka Kikuchi,Emma E M Knowles,Kuldeep Kumar,Stephanie Le Hellard,Costin Leu,David E J Linden,Jingyu Liu,Arvid Lundervold,Astri Johansen Lundervold,Anne M Maillard,Nicholas G Martin,Sandra Martin-Brevet,Karen A Mather,Samuel R Mathias,Katie L McMahon,Allan F McRae,Sarah E Medland,Andreas Meyer-Lindenberg,Torgeir Moberget,Claudia Modenato,Jennifer Monereo Sánchez,Derek W Morris,Thomas W Mühleisen,Robin M Murray,Jacob Nielsen,Jan E Nordvik,Lars Nyberg,Loes M Olde Loohuis,Roel A Ophoff,Michael J Owen,Tomas Paus,Zdenka Pausova,Juan M Peralta,G Bruce Pike,Carlos Prieto,Erin B Quinlan,Céline S Reinbold,Tiago Reis Marques,James J H Rucker,Perminder S Sachdev,Sigrid B Sando,Peter R Schofield,Andrew J Schork,Gunter Schumann,Jean Shin,Elena Shumskaya,Ana I Silva,Sanjay M Sisodiya,Vidar M Steen,Dan J Stein,Lachlan T Strike,Ikuo K Suzuki,Christian K Tamnes,Alexander Teumer,Anbupalam Thalamuthu,Diana Tordesillas-Gutiérrez,Anne Uhlmann,Magnus O Ulfarsson,Dennis van 't Ent,Marianne B M van den Bree,Pierre Vanderhaeghen,Evangelos Vassos,Wei Wen,Katharina Wittfeld,Margaret J Wright,Ingrid Agartz,Srdjan Djurovic,Lars T Westlye,Hreinn Stefansson,Kari Stefansson,Sébastien Jacquemont,Paul M Thompson,Ole A Andreassen,ENIGMA-CNV working group
    Source: Translational psychiatry
  • PADI2-Catalyzed MEK1 Citrullination Activates ERK1/2 and Promotes IGF2BP1-Mediated SOX2 mRNA Stability in Endometrial Cancer

    Monday, March 22, 2021
    Author(s): Teng Xue,Xiaoqiu Liu,Mei Zhang,Qiukai E,Shuting Liu,Maosheng Zou,Ying Li,Zhinan Ma,Yun Han,Paul Thompson,Xuesen Zhang
    Source: Advanced science (Weinheim, Baden-Wurttemberg, Germany)
  • Citrullinated vimentin mediates development and progression of lung fibrosis

    Thursday, March 18, 2021
    Author(s): Fu Jun Li,Ranu Surolia,Huashi Li,Zheng Wang,Gang Liu,Tejaswini Kulkarni,Adriana V F Massicano,James A Mobley,Santanu Mondal,Joao A de Andrade,Scott A Coonrod,Paul R Thompson,Keith Wille,Suzanne E Lapi,Mohammad Athar,Victor J Thannickal,A Brent Carter,Veena B Antony
    Source: Science translational medicine
  • Crystal Structure of SARS-CoV-2 Main Protease in Complex with the Non-Covalent Inhibitor ML188

    Thursday, January 28, 2021
    Author(s): Gordon J Lockbaum,Archie C Reyes,Jeong Min Lee,Ronak Tilvawala,Ellen A Nalivaika,Akbar Ali,Nese Kurt Yilmaz,Paul R Thompson,Celia A Schiffer
    Source: Viruses
  • Peptidylarginine Deiminase Inhibition Prevents Diabetes Development in NOD Mice

    Wednesday, November 18, 2020
    Author(s): Fernanda M C Sodré,Samal Bissenova,Ylke Bruggeman,Ronak Tilvawala,Dana P Cook,Claire Berthault,Santanu Mondal,Aïsha Callebaut,Sylvaine You,Raphael Scharfmann,Roberto Mallone,Paul R Thompson,Chantal Mathieu,Mijke Buitinga,Lut Overbergh
    Source: Diabetes
  • Peptidylarginine deiminase 2 has potential as both a biomarker and therapeutic target of sepsis

    Thursday, October 15, 2020
    Author(s): Yuzi Tian,Shibin Qu,Hasan B Alam,Aaron M Williams,Zhenyu Wu,Qiufang Deng,Baihong Pan,Jing Zhou,Baoling Liu,Xiuzhen Duan,Jianjie Ma,Santanu Mondal,Paul R Thompson,Kathleen A Stringer,Theodore J Standiford,Yongqing Li
    Source: JCI insight
  • Succination inactivates gasdermin D and blocks pyroptosis

    Saturday, August 22, 2020
    Author(s): Fiachra Humphries,Liraz Shmuel-Galia,Natalia Ketelut-Carneiro,Sheng Li,Bingwei Wang,Venkatesh V Nemmara,Ruth Wilson,Zhaozhao Jiang,Farnaz Khalighinejad,Khaja Muneeruddin,Scott A Shaffer,Ranjan Dutta,Carolina Ionete,Scott Pesiridis,Shuo Yang,Paul R Thompson,Katherine A Fitzgerald
    Source: Science (New York, N.Y.)
  • Identification and Characterization of the Lactating Mouse Mammary Gland Citrullinome

    Thursday, April 16, 2020
    Author(s): Guangyuan Li,Coleman H Young,Bryce Snow,Amanda O Christensen,M Kristen Demoruelle,Venkatesh V Nemmara,Paul R Thompson,Heather M Rothfuss,Brian D Cherrington
    Source: International journal of molecular sciences
  • Peptidylarginine Deiminase Isozyme-Specific PAD2, PAD3 and PAD4 Inhibitors Differentially Modulate Extracellular Vesicle Signatures and Cell Invasion in Two Glioblastoma Multiforme Cell Lines

    Thursday, February 27, 2020
    Author(s): Pinar Uysal-Onganer,Amy MacLatchy,Rayan Mahmoud,Igor Kraev,Paul R Thompson,Jameel M Inal,Sigrun Lange
    Source: International journal of molecular sciences
  • Initial Kinetic Characterization of Sterile Alpha and Toll/Interleukin Receptor Motif-Containing Protein 1

    Thursday, February 13, 2020
    Author(s): Heather S Loring,Janneke D Icso,Venkatesh V Nemmara,Paul R Thompson
    Source: Biochemistry
  • Erratum for Research Article "Synovial fibroblast-neutrophil interactions promote pathogenic adaptive immunity in rheumatoid arthritis" by C. Carmona-Rivera, P. M. Carlucci, E. Moore, N. Lingampalli, H. Uchtenhagen, E. James, Y. Liu, K. L. Bicker, H. Wahamma, V. Hoffman, A. I. Catrina, P. Thompson, J. H. Buckner, W. H. Robinson, D. A. Fox, M. J. Kaplan

    Sunday, February 02, 2020
    Author(s): Carmelo Carmona-Rivera,Philip M. Carlucci,Erica Moore,Nithya Lingampalli,Hannes Uchtenhagen,Eddie James,Yudong Liu,Kevin L. Bicker,Heidi Wahamaa,Victoria Hoffmann,Anca Irinel Catrina,Paul R. Thompson,Jane H. Buckner,William H. Robinson,David A. Fox,Mariana J. Kaplan
    Source: Science immunology
  • Emergence of SARM1 as a Potential Therapeutic Target for Wallerian-type Diseases

    Tuesday, November 26, 2019
    Author(s): Heather S Loring,Paul R Thompson
    Source: Cell chemical biology
  • Reciprocal regulation of Th2 and Th17 cells by PAD2-mediated citrullination

    Friday, November 15, 2019
    Author(s): Bo Sun,Hui-Hsin Chang,Ari Salinger,Beverly Tomita,Mandar Bawadekar,Caitlyn L Holmes,Miriam A Shelef,Eranthie Weerapana,Paul R Thompson,I-Cheng Ho
    Source: JCI insight
  • Association of Copy Number Variation of the 15q11.2 BP1-BP2 Region With Cortical and Subcortical Morphology and Cognition

    Thursday, October 31, 2019
    Author(s): Writing Committee for the ENIGMA-CNV Working Group,Dennis van der Meer,Ida E Sønderby,Tobias Kaufmann,G Bragi Walters,Abdel Abdellaoui,David Ames,Katrin Amunts,Micael Andersson,Nicola J Armstrong,Manon Bernard,Nicholas B Blackburn,John Blangero,Dorret I Boomsma,Henry Brodaty,Rachel M Brouwer,Robin Bülow,Wiepke Cahn,Vince D Calhoun,Svenja Caspers,Gianpiero L Cavalleri,Christopher R K Ching,Sven Cichon,Simone Ciufolini,Aiden Corvin,Benedicto Crespo-Facorro,Joanne E Curran,Shareefa Dalvie,Paola Dazzan,Eco J C de Geus,Greig I de Zubicaray,Sonja M C de Zwarte,Norman Delanty,Anouk den Braber,Sylvane Desrivieres,Marta Di Forti,Joanne L Doherty,Gary Donohoe,Stefan Ehrlich,Else Eising,Thomas Espeseth,Simon E Fisher,Tormod Fladby,Oleksandr Frei,Vincent Frouin,Masaki Fukunaga,Thomas Gareau,David C Glahn,Hans J Grabe,Nynke A Groenewold,Ómar Gústafsson,Jan Haavik,Asta K Haberg,Ryota Hashimoto,Jayne Y Hehir-Kwa,Derrek P Hibar,Manon H J Hillegers,Per Hoffmann,Laurena Holleran,Jouke-Jan Hottenga,Hilleke E Hulshoff Pol,Masashi Ikeda,Sébastien Jacquemont,Neda Jahanshad,Christiane Jockwitz,Stefan Johansson,Erik G Jönsson,Masataka Kikuchi,Emma E M Knowles,John B Kwok,Stephanie Le Hellard,David E J Linden,Jingyu Liu,Arvid Lundervold,Astri J Lundervold,Nicholas G Martin,Karen A Mather,Samuel R Mathias,Katie L McMahon,Allan F McRae,Sarah E Medland,Torgeir Moberget,Clara Moreau,Derek W Morris,Thomas W Mühleisen,Robin M Murray,Jan E Nordvik,Lars Nyberg,Loes M Olde Loohuis,Roel A Ophoff,Michael J Owen,Tomas Paus,Zdenka Pausova,Juan M Peralta,Bruce Pike,Carlos Prieto,Erin Burke Quinlan,Céline S Reinbold,Tiago Reis Marques,James J H Rucker,Perminder S Sachdev,Sigrid B Sando,Peter R Schofield,Andrew J Schork,Gunter Schumann,Jean Shin,Elena Shumskaya,Ana I Silva,Sanjay M Sisodiya,Vidar M Steen,Dan J Stein,Lachlan T Strike,Christian K Tamnes,Alexander Teumer,Anbupalam Thalamuthu,Diana Tordesillas-Gutiérrez,Anne Uhlmann,Magnús Ö Úlfarsson,Dennis van 't Ent,Marianne B M van den Bree,Evangelos Vassos,Wei Wen,Katharina Wittfeld,Margaret J Wright,Tetyana Zayats,Anders M Dale,Srdjan Djurovic,Ingrid Agartz,Lars T Westlye,Hreinn Stefánsson,Kári Stefánsson,Paul M Thompson,Ole A Andreassen
    Source: JAMA psychiatry
  • Genetic architecture of subcortical brain structures in 38,851 individuals

    Wednesday, October 23, 2019
    Author(s): Claudia L Satizabal,Hieab H H Adams,Derrek P Hibar,Charles C White,Maria J Knol,Jason L Stein,Markus Scholz,Muralidharan Sargurupremraj,Neda Jahanshad,Gennady V Roshchupkin,Albert V Smith,Joshua C Bis,Xueqiu Jian,Michelle Luciano,Edith Hofer,Alexander Teumer,Sven J van der Lee,Jingyun Yang,Lisa R Yanek,Tom V Lee,Shuo Li,Yanhui Hu,Jia Yu Koh,John D Eicher,Sylvane Desrivières,Alejandro Arias-Vasquez,Ganesh Chauhan,Lavinia Athanasiu,Miguel E Rentería,Sungeun Kim,David Hoehn,Nicola J Armstrong,Qiang Chen,Avram J Holmes,Anouk den Braber,Iwona Kloszewska,Micael Andersson,Thomas Espeseth,Oliver Grimm,Lucija Abramovic,Saud Alhusaini,Yuri Milaneschi,Martina Papmeyer,Tomas Axelsson,Stefan Ehrlich,Roberto Roiz-Santiañez,Bernd Kraemer,Asta K Håberg,Hannah J Jones,G Bruce Pike,Dan J Stein,Allison Stevens,Janita Bralten,Meike W Vernooij,Tamara B Harris,Irina Filippi,A Veronica Witte,Tulio Guadalupe,Katharina Wittfeld,Thomas H Mosley,James T Becker,Nhat Trung Doan,Saskia P Hagenaars,Yasaman Saba,Gabriel Cuellar-Partida,Najaf Amin,Saima Hilal,Kwangsik Nho,Nazanin Mirza-Schreiber,Konstantinos Arfanakis,Diane M Becker,David Ames,Aaron L Goldman,Phil H Lee,Dorret I Boomsma,Simon Lovestone,Sudheer Giddaluru,Stephanie Le Hellard,Manuel Mattheisen,Marc M Bohlken,Dalia Kasperaviciute,Lianne Schmaal,Stephen M Lawrie,Ingrid Agartz,Esther Walton,Diana Tordesillas-Gutierrez,Gareth E Davies,Jean Shin,Jonathan C Ipser,Louis N Vinke,Martine Hoogman,Tianye Jia,Ralph Burkhardt,Marieke Klein,Fabrice Crivello,Deborah Janowitz,Owen Carmichael,Unn K Haukvik,Benjamin S Aribisala,Helena Schmidt,Lachlan T Strike,Ching-Yu Cheng,Shannon L Risacher,Benno Pütz,Debra A Fleischman,Amelia A Assareh,Venkata S Mattay,Randy L Buckner,Patrizia Mecocci,Anders M Dale,Sven Cichon,Marco P Boks,Mar Matarin,Brenda W J H Penninx,Vince D Calhoun,M Mallar Chakravarty,Andre F Marquand,Christine Macare,Shahrzad Kharabian Masouleh,Jaap Oosterlaan,Philippe Amouyel,Katrin Hegenscheid,Jerome I Rotter,Andrew J Schork,David C M Liewald,Greig I de Zubicaray,Tien Yin Wong,Li Shen,Philipp G Sämann,Henry Brodaty,Joshua L Roffman,Eco J C de Geus,Magda Tsolaki,Susanne Erk,Kristel R van Eijk,Gianpiero L Cavalleri,Nic J A van der Wee,Andrew M McIntosh,Randy L Gollub,Kazima B Bulayeva,Manon Bernard,Jennifer S Richards,Jayandra J Himali,Markus Loeffler,Nanda Rommelse,Wolfgang Hoffmann,Lars T Westlye,Maria C Valdés Hernández,Narelle K Hansell,Theo G M van Erp,Christiane Wolf,John B J Kwok,Bruno Vellas,Andreas Heinz,Loes M Olde Loohuis,Norman Delanty,Beng-Choon Ho,Christopher R K Ching,Elena Shumskaya,Baljeet Singh,Albert Hofman,Dennis van der Meer,Georg Homuth,Bruce M Psaty,Mark E Bastin,Grant W Montgomery,Tatiana M Foroud,Simone Reppermund,Jouke-Jan Hottenga,Andrew Simmons,Andreas Meyer-Lindenberg,Wiepke Cahn,Christopher D Whelan,Marjolein M J van Donkelaar,Qiong Yang,Norbert Hosten,Robert C Green,Anbupalam Thalamuthu,Sebastian Mohnke,Hilleke E Hulshoff Pol,Honghuang Lin,Clifford R Jack,Peter R Schofield,Thomas W Mühleisen,Pauline Maillard,Steven G Potkin,Wei Wen,Evan Fletcher,Arthur W Toga,Oliver Gruber,Matthew Huentelman,George Davey Smith,Lenore J Launer,Lars Nyberg,Erik G Jönsson,Benedicto Crespo-Facorro,Nastassja Koen,Douglas N Greve,André G Uitterlinden,Daniel R Weinberger,Vidar M Steen,Iryna O Fedko,Nynke A Groenewold,Wiro J Niessen,Roberto Toro,Christophe Tzourio,William T Longstreth,M Kamran Ikram,Jordan W Smoller,Marie-Jose van Tol,Jessika E Sussmann,Tomas Paus,Hervé Lemaître,Matthias L Schroeter,Bernard Mazoyer,Ole A Andreassen,Florian Holsboer,Chantal Depondt,Dick J Veltman,Jessica A Turner,Zdenka Pausova,Gunter Schumann,Daan van Rooij,Srdjan Djurovic,Ian J Deary,Katie L McMahon,Bertram Müller-Myhsok,Rachel M Brouwer,Hilkka Soininen,Massimo Pandolfo,Thomas H Wassink,Joshua W Cheung,Thomas Wolfers,Jean-Luc Martinot,Marcel P Zwiers,Matthias Nauck,Ingrid Melle,Nicholas G Martin,Ryota Kanai,Eric Westman,René S Kahn,Sanjay M Sisodiya,Tonya White,Arvin Saremi,Hans van Bokhoven,Han G Brunner,Henry Völzke,Margaret J Wright,Dennis van 't Ent,Markus M Nöthen,Roel A Ophoff,Jan K Buitelaar,Guillén Fernández,Perminder S Sachdev,Marcella Rietschel,Neeltje E M van Haren,Simon E Fisher,Alexa S Beiser,Clyde Francks,Andrew J Saykin,Karen A Mather,Nina Romanczuk-Seiferth,Catharina A Hartman,Anita L DeStefano,Dirk J Heslenfeld,Michael W Weiner,Henrik Walter,Pieter J Hoekstra,Paul A Nyquist,Barbara Franke,David A Bennett,Hans J Grabe,Andrew D Johnson,Christopher Chen,Cornelia M van Duijn,Oscar L Lopez,Myriam Fornage,Joanna M Wardlaw,Reinhold Schmidt,Charles DeCarli,Philip L De Jager,Arno Villringer,Stéphanie Debette,Vilmundur Gudnason,Sarah E Medland,Joshua M Shulman,Paul M Thompson,Sudha Seshadri,M Arfan Ikram
    Source: Nature genetics
  • Inhibiting PAD2 enhances the anti-tumor effect of docetaxel in tamoxifen-resistant breast cancer cells

    Saturday, October 12, 2019
    Author(s): Fujun Li,Lixia Miao,Teng Xue,Hao Qin,Santanu Mondal,Paul R Thompson,Scott A Coonrod,Xiaoqiu Liu,Xuesen Zhang
    Source: Journal of experimental & clinical cancer research : CR
  • Cutting Edge: Protein Arginine Deiminase 2 and 4 Regulate NLRP3 Inflammasome-Dependent IL-1β Maturation and ASC Speck Formation in Macrophages

    Friday, July 12, 2019
    Author(s): Neha Mishra,Lidja Schwerdtner,Kelly Sams,Santanu Mondal,Fareed Ahmad,Reinhold E Schmidt,Scott A Coonrod,Paul R Thompson,Markus M Lerch,Lukas Bossaller
    Source: Journal of immunology (Baltimore, Md. : 1950)
  • Halogen Bonding Increases the Potency and Isozyme Selectivity of Protein Arginine Deiminase 1 Inhibitors

    Saturday, July 06, 2019
    Author(s): Santanu Mondal,Xuefeng Gong,Xiaoqian Zhang,Ari J Salinger,Li Zheng,Sudeshna Sen,Eranthie Weerapana,Xuesen Zhang,Paul R Thompson
    Source: Angewandte Chemie (International ed. in English)
  • Calcium Regulates the Nuclear Localization of Protein Arginine Deiminase 2

    Friday, June 28, 2019
    Author(s): Li Zheng,Mitesh Nagar,Aaron J Maurais,Daniel J Slade,Sangram S Parelkar,Scott A Coonrod,Eranthie Weerapana,Paul R Thompson
    Source: Biochemistry
  • Development of a Suicide Inhibition-Based Protein Labeling Strategy for Nicotinamide N-Methyltransferase

    Tuesday, April 02, 2019
    Author(s): Sudeshna Sen,Santanu Mondal,Li Zheng,Ari J Salinger,Walter Fast,Eranthie Weerapana,Paul R Thompson
    Source: ACS chemical biology
  • Peptidylarginine Deiminase Inhibitor Cl-Amidine Attenuates Cornification and Interferes with the Regulation of Autophagy in Reconstructed Human Epidermis

    Monday, March 18, 2019
    Author(s): Laura Cau,Hidenari Takahara,Paul R Thompson,Guy Serre,Marie-Claire Méchin,Michel Simon
    Source: The Journal of investigative dermatology
  • Thioredoxin Modulates Protein Arginine Deiminase 4 (PAD4)-Catalyzed Citrullination

    Tuesday, March 12, 2019
    Author(s): Mitesh Nagar,Ronak Tilvawala,Paul R Thompson
    Source: Frontiers in immunology
  • Protein Arginine Deiminases (PADs): Biochemistry and Chemical Biology of Protein Citrullination

    Friday, March 08, 2019
    Author(s): Santanu Mondal,Paul R Thompson
    Source: Accounts of chemical research
  • Peptidyl arginine deiminases: detection and functional analysis of protein citrullination

    Wednesday, March 06, 2019
    Author(s): Ronak Tilvawala,Paul R Thompson
    Source: Current opinion in structural biology
  • Correction: Dose response of the 16p11.2 distal copy number variant on intracranial volume and basal ganglia

    Saturday, February 02, 2019
    Author(s): Ida E Sønderby,Ómar Gústafsson,Nhat Trung Doan,Derrek P Hibar,Sandra Martin-Brevet,Abdel Abdellaoui,David Ames,Katrin Amunts,Michael Andersson,Nicola J Armstrong,Manon Bernard,Nicholas Blackburn,John Blangero,Dorret I Boomsma,Janita Bralten,Hans-Richard Brattbak,Henry Brodaty,Rachel M Brouwer,Robin Bülow,Vince Calhoun,Svenja Caspers,Gianpiero Cavalleri,Chi-Hua Chen,Sven Cichon,Simone Ciufolini,Aiden Corvin,Benedicto Crespo-Facorro,Joanne E Curran,Anders M Dale,Shareefa Dalvie,Paola Dazzan,Eco J C de Geus,Greig I de Zubicaray,Sonja M C de Zwarte,Norman Delanty,Anouk den Braber,Sylvane Desrivières,Gary Donohoe,Bogdan Draganski,Stefan Ehrlich,Thomas Espeseth,Simon E Fisher,Barbara Franke,Vincent Frouin,Masaki Fukunaga,Thomas Gareau,David C Glahn,Hans Grabe,Nynke A Groenewold,Jan Haavik,Asta Håberg,Ryota Hashimoto,Jayne Y Hehir-Kwa,Andreas Heinz,Manon H J Hillegers,Per Hoffmann,Laurena Holleran,Jouke-Jan Hottenga,Hilleke E Hulshoff,Masashi Ikeda,Neda Jahanshad,Terry Jernigan,Christiane Jockwitz,Stefan Johansson,Gudrun A Jonsdottir,Erik G Jönsson,Rene Kahn,Tobias Kaufmann,Sinead Kelly,Masataka Kikuchi,Emma E M Knowles,Knut K Kolskår,John B Kwok,Stephanie Le Hellard,Costin Leu,Jingyu Liu,Astri J Lundervold,Arvid Lundervold,Nicholas G Martin,Karen Mather,Samuel R Mathias,Mark McCormack,Katie L McMahon,Allan McRae,Yuri Milaneschi,Clara Moreau,Derek Morris,David Mothersill,Thomas W Mühleisen,Robin Murray,Jan E Nordvik,Lars Nyberg,Loes M Olde Loohuis,Roel Ophoff,Tomas Paus,Zdenka Pausova,Brenda Penninx,Juan M Peralta,Bruce Pike,Carlos Prieto,Sara Pudas,Erin Quinlan,Daniel S Quintana,Céline S Reinbold,Tiago Reis Marques,Alexandre Reymond,Genevieve Richard,Borja Rodriguez-Herreros,Roberto Roiz-Santiañez,Jarek Rokicki,James Rucker,Perminder Sachdev,Anne-Marthe Sanders,Sigrid B Sando,Lianne Schmaal,Peter R Schofield,Andrew J Schork,Gunter Schumann,Jean Shin,Elena Shumskaya,Sanjay Sisodiya,Vidar M Steen,Dan J Stein,Stacy Steinberg,Lachlan Strike,Alexander Teumer,Anbu Thalamuthu,Diana Tordesillas-Gutierrez,Jessica Turner,Torill Ueland,Anne Uhlmann,Magnus O Ulfarsson,Dennis van 't Ent,Dennis van der Meer,Neeltje E M van Haren,Anja Vaskinn,Evangelos Vassos,G Bragi Walters,Yunpeng Wang,Wei Wen,Christopher D Whelan,Katharina Wittfeld,Margie Wright,Hidenaga Yamamori,Tetyana Zayats,Ingrid Agartz,Lars T Westlye,Sébastien Jacquemont,Srdjan Djurovic,Hreinn Stefánsson,Kári Stefánsson,Paul Thompson,Ole A Andreassen,16p11.2 European Consortium, for the ENIGMA-CNV working group
    Source: Molecular psychiatry
  • Dose response of the 16p11.2 distal copy number variant on intracranial volume and basal ganglia

    Friday, October 05, 2018
    Author(s): Ida E Sønderby,Ómar Gústafsson,Nhat Trung Doan,Derrek P Hibar,Sandra Martin-Brevet,Abdel Abdellaoui,David Ames,Katrin Amunts,Michael Andersson,Nicola J Armstrong,Manon Bernard,Nicholas Blackburn,John Blangero,Dorret I Boomsma,Janita Bralten,Hans-Richard Brattbak,Henry Brodaty,Rachel M Brouwer,Robin Bülow,Vince Calhoun,Svenja Caspers,Gianpiero Cavalleri,Chi-Hua Chen,Sven Cichon,Simone Ciufolini,Aiden Corvin,Benedicto Crespo-Facorro,Joanne E Curran,Anders M Dale,Shareefa Dalvie,Paola Dazzan,Eco J C de Geus,Greig I de Zubicaray,Sonja M C de Zwarte,Norman Delanty,Anouk den Braber,Sylvane Desrivières,Gary Donohoe,Bogdan Draganski,Stefan Ehrlich,Thomas Espeseth,Simon E Fisher,Barbara Franke,Vincent Frouin,Masaki Fukunaga,Thomas Gareau,David C Glahn,Hans Grabe,Nynke A Groenewold,Jan Haavik,Asta Håberg,Ryota Hashimoto,Jayne Y Hehir-Kwa,Andreas Heinz,Manon H J Hillegers,Per Hoffmann,Laurena Holleran,Jouke-Jan Hottenga,Hilleke E Hulshoff,Masashi Ikeda,Neda Jahanshad,Terry Jernigan,Christiane Jockwitz,Stefan Johansson,Gudrun A Jonsdottir,Erik G Jönsson,Rene Kahn,Tobias Kaufmann,Sinead Kelly,Masataka Kikuchi,Emma E M Knowles,Knut K Kolskår,John B Kwok,Stephanie Le Hellard,Costin Leu,Jingyu Liu,Astri J Lundervold,Arvid Lundervold,Nicholas G Martin,Karen Mather,Samuel R Mathias,Mark McCormack,Katie L McMahon,Allan McRae,Yuri Milaneschi,Clara Moreau,Derek Morris,David Mothersill,Thomas W Mühleisen,Robin Murray,Jan E Nordvik,Lars Nyberg,Loes M Olde Loohuis,Roel Ophoff,Tomas Paus,Zdenka Pausova,Brenda Penninx,Juan M Peralta,Bruce Pike,Carlos Prieto,Sara Pudas,Erin Quinlan,Daniel S Quintana,Céline S Reinbold,Tiago Reis Marques,Alexandre Reymond,Genevieve Richard,Borja Rodriguez-Herreros,Roberto Roiz-Santiañez,Jarek Rokicki,James Rucker,Perminder Sachdev,Anne-Marthe Sanders,Sigrid B Sando,Lianne Schmaal,Peter R Schofield,Andrew J Schork,Gunter Schumann,Jean Shin,Elena Shumskaya,Sanjay Sisodiya,Vidar M Steen,Dan J Stein,Stacy Steinberg,Lachlan Strike,Alexander Teumer,Anbu Thalamuthu,Diana Tordesillas-Gutierrez,Jessica Turner,Torill Ueland,Anne Uhlmann,Magnus O Ulfarsson,Dennis van 't Ent,Dennis van der Meer,Neeltje E M van Haren,Anja Vaskinn,Evangelos Vassos,G Bragi Walters,Yunpeng Wang,Wei Wen,Christopher D Whelan,Katharina Wittfeld,Margie Wright,Hidenaga Yamamori,Tetyana Zayats,Ingrid Agartz,Lars T Westlye,Sébastien Jacquemont,Srdjan Djurovic,Hreinn Stefánsson,Kári Stefánsson,Paul Thompson,Ole A Andreassen,16p11.2 European Consortium, for the ENIGMA-CNV working group
    Source: Molecular psychiatry
  • Development of Activity-Based Proteomic Probes for Protein Citrullination

    Wednesday, September 12, 2018
    Author(s): Venkatesh V Nemmara,Paul R Thompson
    Source: Current topics in microbiology and immunology
  • Kinetic Mechanism of Nicotinamide N-Methyltransferase

    Tuesday, August 28, 2018
    Author(s): Heather S Loring,Paul R Thompson
    Source: Biochemistry
  • Citrullination Inactivates Nicotinamide- N-methyltransferase

    Thursday, July 26, 2018
    Author(s): Venkatesh V Nemmara,Ronak Tilvawala,Ari J Salinger,Lacey Miller,Son Hong Nguyen,Eranthie Weerapana,Paul R Thompson
    Source: ACS chemical biology
  • Histone Citrullination Represses MicroRNA Expression, Resulting in Increased Oncogene mRNAs in Somatolactotrope Cells

    Wednesday, July 11, 2018
    Author(s): Stanley B DeVore,Coleman H Young,Guangyuan Li,Anitha Sundararajan,Thiruvarangan Ramaraj,Joann Mudge,Faye Schilkey,Aaron Muth,Paul R Thompson,Brian D Cherrington
    Source: Molecular and cellular biology
  • Cortical Brain Abnormalities in 4474 Individuals With Schizophrenia and 5098 Control Subjects via the Enhancing Neuro Imaging Genetics Through Meta Analysis (ENIGMA) Consortium

    Monday, July 02, 2018
    Author(s): Theo G M van Erp,Esther Walton,Derrek P Hibar,Lianne Schmaal,Wenhao Jiang,David C Glahn,Godfrey D Pearlson,Nailin Yao,Masaki Fukunaga,Ryota Hashimoto,Naohiro Okada,Hidenaga Yamamori,Juan R Bustillo,Vincent P Clark,Ingrid Agartz,Bryon A Mueller,Wiepke Cahn,Sonja M C de Zwarte,Hilleke E Hulshoff Pol,René S Kahn,Roel A Ophoff,Neeltje E M van Haren,Ole A Andreassen,Anders M Dale,Nhat Trung Doan,Tiril P Gurholt,Cecilie B Hartberg,Unn K Haukvik,Kjetil N Jørgensen,Trine V Lagerberg,Ingrid Melle,Lars T Westlye,Oliver Gruber,Bernd Kraemer,Anja Richter,David Zilles,Vince D Calhoun,Benedicto Crespo-Facorro,Roberto Roiz-Santiañez,Diana Tordesillas-Gutiérrez,Carmel Loughland,Vaughan J Carr,Stanley Catts,Vanessa L Cropley,Janice M Fullerton,Melissa J Green,Frans A Henskens,Assen Jablensky,Rhoshel K Lenroot,Bryan J Mowry,Patricia T Michie,Christos Pantelis,Yann Quidé,Ulrich Schall,Rodney J Scott,Murray J Cairns,Marc Seal,Paul A Tooney,Paul E Rasser,Gavin Cooper,Cynthia Shannon Weickert,Thomas W Weickert,Derek W Morris,Elliot Hong,Peter Kochunov,Lauren M Beard,Raquel E Gur,Ruben C Gur,Theodore D Satterthwaite,Daniel H Wolf,Aysenil Belger,Gregory G Brown,Judith M Ford,Fabio Macciardi,Daniel H Mathalon,Daniel S O'Leary,Steven G Potkin,Adrian Preda,James Voyvodic,Kelvin O Lim,Sarah McEwen,Fude Yang,Yunlong Tan,Shuping Tan,Zhiren Wang,Fengmei Fan,Jingxu Chen,Hong Xiang,Shiyou Tang,Hua Guo,Ping Wan,Dong Wei,Henry J Bockholt,Stefan Ehrlich,Rick P F Wolthusen,Margaret D King,Jody M Shoemaker,Scott R Sponheim,Lieuwe De Haan,Laura Koenders,Marise W Machielsen,Therese van Amelsvoort,Dick J Veltman,Francesca Assogna,Nerisa Banaj,Pietro de Rossi,Mariangela Iorio,Fabrizio Piras,Gianfranco Spalletta,Peter J McKenna,Edith Pomarol-Clotet,Raymond Salvador,Aiden Corvin,Gary Donohoe,Sinead Kelly,Christopher D Whelan,Erin W Dickie,David Rotenberg,Aristotle N Voineskos,Simone Ciufolini,Joaquim Radua,Paola Dazzan,Robin Murray,Tiago Reis Marques,Andrew Simmons,Stefan Borgwardt,Laura Egloff,Fabienne Harrisberger,Anita Riecher-Rössler,Renata Smieskova,Kathryn I Alpert,Lei Wang,Erik G Jönsson,Sanne Koops,Iris E C Sommer,Alessandro Bertolino,Aurora Bonvino,Annabella Di Giorgio,Emma Neilson,Andrew R Mayer,Julia M Stephen,Jun Soo Kwon,Je-Yeon Yun,Dara M Cannon,Colm McDonald,Irina Lebedeva,Alexander S Tomyshev,Tolibjohn Akhadov,Vasily Kaleda,Helena Fatouros-Bergman,Lena Flyckt,Karolinska Schizophrenia Project,Geraldo F Busatto,Pedro G P Rosa,Mauricio H Serpa,Marcus V Zanetti,Cyril Hoschl,Antonin Skoch,Filip Spaniel,David Tomecek,Saskia P Hagenaars,Andrew M McIntosh,Heather C Whalley,Stephen M Lawrie,Christian Knöchel,Viola Oertel-Knöchel,Michael Stäblein,Fleur M Howells,Dan J Stein,Henk S Temmingh,Anne Uhlmann,Carlos Lopez-Jaramillo,Danai Dima,Agnes McMahon,Joshua I Faskowitz,Boris A Gutman,Neda Jahanshad,Paul M Thompson,Jessica A Turner
    Source: Biological psychiatry
  • Donated chemical probes for open science

    Saturday, April 21, 2018
    Author(s): Susanne Müller,Suzanne Ackloo,Cheryl H Arrowsmith,Marcus Bauser,Jeremy L Baryza,Julian Blagg,Jark Böttcher,Chas Bountra,Peter J Brown,Mark E Bunnage,Adrian J Carter,David Damerell,Volker Dötsch,David H Drewry,Aled M Edwards,James Edwards,Jon M Elkins,Christian Fischer,Stephen V Frye,Andreas Gollner,Charles E Grimshaw,Adriaan IJzerman,Thomas Hanke,Ingo V Hartung,Steve Hitchcock,Trevor Howe,Terry V Hughes,Stefan Laufer,Volkhart Mj Li,Spiros Liras,Brian D Marsden,Hisanori Matsui,John Mathias,Ronan C O'Hagan,Dafydd R Owen,Vineet Pande,Daniel Rauh,Saul H Rosenberg,Bryan L Roth,Natalie S Schneider,Cora Scholten,Kumar Singh Saikatendu,Anton Simeonov,Masayuki Takizawa,Chris Tse,Paul R Thompson,Daniel K Treiber,Amélia Yi Viana,Carrow I Wells,Timothy M Willson,William J Zuercher,Stefan Knapp,Anke Mueller-Fahrnow
    Source: eLife
  • BB-Cl-Amidine as a novel therapeutic for canine and feline mammary cancer via activation of the endoplasmic reticulum stress pathway

    Saturday, April 14, 2018
    Author(s): Melissa M Ledet,Robyn Anderson,Rebecca Harman,Aaron Muth,Paul R Thompson,Scott A Coonrod,Gerlinde R Van de Walle
    Source: BMC cancer
  • The Rheumatoid Arthritis-Associated Citrullinome

    Tuesday, April 10, 2018
    Author(s): Ronak Tilvawala,Son Hong Nguyen,Aaron J Maurais,Venkatesh V Nemmara,Mitesh Nagar,Ari J Salinger,Sunil Nagpal,Eranthie Weerapana,Paul R Thompson
    Source: Cell chemical biology
  • Response to comment on "Synovial fibroblast-neutrophil interactions promote pathogenic adaptive immunity in rheumatoid arthritis"

    Sunday, April 01, 2018
    Author(s): Carmelo Carmona-Rivera,Kevin L Bicker,Paul R Thompson,Jane H Buckner,William H Robinson,David A Fox,Mariana J Kaplan
    Source: Science immunology
  • Citrullination regulates the expression of insulin-like growth factor-binding protein 1 (IGFBP1) in ovine uterine luminal epithelial cells

    Friday, March 23, 2018
    Author(s): Coleman H Young,Heather M Rothfuss,Philip F Gard,Aaron Muth,Paul R Thompson,Ryan L Ashley,Brian D Cherrington
    Source: Reproduction (Cambridge, England)
  • Photochemical Control of Protein Arginine Deiminase (PAD) Activity

    Friday, March 09, 2018
    Author(s): Santanu Mondal,Sangram S Parelkar,Mitesh Nagar,Paul R Thompson
    Source: ACS chemical biology
  • The Development of Benzimidazole-Based Clickable Probes for the Efficient Labeling of Cellular Protein Arginine Deiminases (PADs)

    Thursday, January 18, 2018
    Author(s): Venkatesh V Nemmara,Venkataraman Subramanian,Aaron Muth,Santanu Mondal,Ari J Salinger,Aaron J Maurais,Ronak Tilvawala,Eranthie Weerapana,Paul R Thompson
    Source: ACS chemical biology
  • PAD1 promotes epithelial-mesenchymal transition and metastasis in triple-negative breast cancer cells by regulating MEK1-ERK1/2-MMP2 signaling

    Tuesday, August 29, 2017
    Author(s): Hao Qin,Xiaoqiu Liu,Fujun Li,Lixia Miao,Tingting Li,Boqun Xu,Xiaofei An,Aaron Muth,Paul R Thompson,Scott A Coonrod,Xuesen Zhang
    Source: Cancer letters
  • Citrullination of NF-κB p65 promotes its nuclear localization and TLR-induced expression of IL-1β and TNFα

    Tuesday, August 08, 2017
    Author(s): Bo Sun,Nishant Dwivedi,Tyler J Bechtel,Janet L Paulsen,Aaron Muth,Mandar Bawadekar,Gang Li,Paul R Thompson,Miriam A Shelef,Celia A Schiffer,Eranthie Weerapana,I-Cheng Ho
    Source: Science immunology
  • Diverse stimuli engage different neutrophil extracellular trap pathways

    Saturday, June 03, 2017
    Author(s): Elaine F Kenny,Alf Herzig,Renate Krüger,Aaron Muth,Santanu Mondal,Paul R Thompson,Volker Brinkmann,Horst von Bernuth,Arturo Zychlinsky
    Source: eLife
  • Role of peptidylarginine deiminase 2 (PAD2) in mammary carcinoma cell migration

    Sunday, May 28, 2017
    Author(s): Sachi Horibata,Katherine E Rogers,David Sadegh,Lynne J Anguish,John L McElwee,Pragya Shah,Paul R Thompson,Scott A Coonrod
    Source: BMC cancer
  • Chloramidine/Bisindolylmaleimide-I-Mediated Inhibition of Exosome and Microvesicle Release and Enhanced Efficacy of Cancer Chemotherapy

    Wednesday, May 10, 2017
    Author(s): Uchini S Kosgodage,Rita P Trindade,Paul R Thompson,Jameel M Inal,Sigrun Lange
    Source: International journal of molecular sciences
  • Citrullination/Methylation Crosstalk on Histone H3 Regulates ER-Target Gene Transcription

    Wednesday, May 10, 2017
    Author(s): Kathleen W Clancy,Anna-Maria Russell,Venkataraman Subramanian,Hannah Nguyen,Yuewei Qian,Robert M Campbell,Paul R Thompson
    Source: ACS chemical biology
  • Development of a Selective Inhibitor of Protein Arginine Deiminase 2

    Thursday, March 23, 2017
    Author(s): Aaron Muth,Venkataraman Subramanian,Edward Beaumont,Mitesh Nagar,Philip Kerry,Paul McEwan,Hema Srinath,Kathleen Clancy,Sangram Parelkar,Paul R Thompson
    Source: Journal of medicinal chemistry
  • Lowering relative humidity level increases epidermal protein deimination and drives human filaggrin breakdown

    Wednesday, March 01, 2017
    Author(s): Laura Cau,Valérie Pendaries,Emeline Lhuillier,Paul R Thompson,Guy Serre,Hidenari Takahara,Marie-Claire Méchin,Michel Simon
    Source: Journal of dermatological science
  • Novel genetic loci associated with hippocampal volume

    Thursday, January 19, 2017
    Author(s): Derrek P Hibar,Hieab H H Adams,Neda Jahanshad,Ganesh Chauhan,Jason L Stein,Edith Hofer,Miguel E Renteria,Joshua C Bis,Alejandro Arias-Vasquez,M Kamran Ikram,Sylvane Desrivières,Meike W Vernooij,Lucija Abramovic,Saud Alhusaini,Najaf Amin,Micael Andersson,Konstantinos Arfanakis,Benjamin S Aribisala,Nicola J Armstrong,Lavinia Athanasiu,Tomas Axelsson,Ashley H Beecham,Alexa Beiser,Manon Bernard,Susan H Blanton,Marc M Bohlken,Marco P Boks,Janita Bralten,Adam M Brickman,Owen Carmichael,M Mallar Chakravarty,Qiang Chen,Christopher R K Ching,Vincent Chouraki,Gabriel Cuellar-Partida,Fabrice Crivello,Anouk Den Braber,Nhat Trung Doan,Stefan Ehrlich,Sudheer Giddaluru,Aaron L Goldman,Rebecca F Gottesman,Oliver Grimm,Michael E Griswold,Tulio Guadalupe,Boris A Gutman,Johanna Hass,Unn K Haukvik,David Hoehn,Avram J Holmes,Martine Hoogman,Deborah Janowitz,Tianye Jia,Kjetil N Jørgensen,Nazanin Karbalai,Dalia Kasperaviciute,Sungeun Kim,Marieke Klein,Bernd Kraemer,Phil H Lee,David C M Liewald,Lorna M Lopez,Michelle Luciano,Christine Macare,Andre F Marquand,Mar Matarin,Karen A Mather,Manuel Mattheisen,David R McKay,Yuri Milaneschi,Susana Muñoz Maniega,Kwangsik Nho,Allison C Nugent,Paul Nyquist,Loes M Olde Loohuis,Jaap Oosterlaan,Martina Papmeyer,Lukas Pirpamer,Benno Pütz,Adaikalavan Ramasamy,Jennifer S Richards,Shannon L Risacher,Roberto Roiz-Santiañez,Nanda Rommelse,Stefan Ropele,Emma J Rose,Natalie A Royle,Tatjana Rundek,Philipp G Sämann,Arvin Saremi,Claudia L Satizabal,Lianne Schmaal,Andrew J Schork,Li Shen,Jean Shin,Elena Shumskaya,Albert V Smith,Emma Sprooten,Lachlan T Strike,Alexander Teumer,Diana Tordesillas-Gutierrez,Roberto Toro,Daniah Trabzuni,Stella Trompet,Dhananjay Vaidya,Jeroen Van der Grond,Sven J Van der Lee,Dennis Van der Meer,Marjolein M J Van Donkelaar,Kristel R Van Eijk,Theo G M Van Erp,Daan Van Rooij,Esther Walton,Lars T Westlye,Christopher D Whelan,Beverly G Windham,Anderson M Winkler,Katharina Wittfeld,Girma Woldehawariat,Christiane Wolf,Thomas Wolfers,Lisa R Yanek,Jingyun Yang,Alex Zijdenbos,Marcel P Zwiers,Ingrid Agartz,Laura Almasy,David Ames,Philippe Amouyel,Ole A Andreassen,Sampath Arepalli,Amelia A Assareh,Sandra Barral,Mark E Bastin,Diane M Becker,James T Becker,David A Bennett,John Blangero,Hans van Bokhoven,Dorret I Boomsma,Henry Brodaty,Rachel M Brouwer,Han G Brunner,Randy L Buckner,Jan K Buitelaar,Kazima B Bulayeva,Wiepke Cahn,Vince D Calhoun,Dara M Cannon,Gianpiero L Cavalleri,Ching-Yu Cheng,Sven Cichon,Mark R Cookson,Aiden Corvin,Benedicto Crespo-Facorro,Joanne E Curran,Michael Czisch,Anders M Dale,Gareth E Davies,Anton J M De Craen,Eco J C De Geus,Philip L De Jager,Greig I De Zubicaray,Ian J Deary,Stéphanie Debette,Charles DeCarli,Norman Delanty,Chantal Depondt,Anita DeStefano,Allissa Dillman,Srdjan Djurovic,Gary Donohoe,Wayne C Drevets,Ravi Duggirala,Thomas D Dyer,Christian Enzinger,Susanne Erk,Thomas Espeseth,Iryna O Fedko,Guillén Fernández,Luigi Ferrucci,Simon E Fisher,Debra A Fleischman,Ian Ford,Myriam Fornage,Tatiana M Foroud,Peter T Fox,Clyde Francks,Masaki Fukunaga,J Raphael Gibbs,David C Glahn,Randy L Gollub,Harald H H Göring,Robert C Green,Oliver Gruber,Vilmundur Gudnason,Sebastian Guelfi,Asta K Håberg,Narelle K Hansell,John Hardy,Catharina A Hartman,Ryota Hashimoto,Katrin Hegenscheid,Andreas Heinz,Stephanie Le Hellard,Dena G Hernandez,Dirk J Heslenfeld,Beng-Choon Ho,Pieter J Hoekstra,Wolfgang Hoffmann,Albert Hofman,Florian Holsboer,Georg Homuth,Norbert Hosten,Jouke-Jan Hottenga,Matthew Huentelman,Hilleke E Hulshoff Pol,Masashi Ikeda,Clifford R Jack,Mark Jenkinson,Robert Johnson,Erik G Jönsson,J Wouter Jukema,René S Kahn,Ryota Kanai,Iwona Kloszewska,David S Knopman,Peter Kochunov,John B Kwok,Stephen M Lawrie,Hervé Lemaître,Xinmin Liu,Dan L Longo,Oscar L Lopez,Simon Lovestone,Oliver Martinez,Jean-Luc Martinot,Venkata S Mattay,Colm McDonald,Andrew M McIntosh,Francis J McMahon,Katie L McMahon,Patrizia Mecocci,Ingrid Melle,Andreas Meyer-Lindenberg,Sebastian Mohnke,Grant W Montgomery,Derek W Morris,Thomas H Mosley,Thomas W Mühleisen,Bertram Müller-Myhsok,Michael A Nalls,Matthias Nauck,Thomas E Nichols,Wiro J Niessen,Markus M Nöthen,Lars Nyberg,Kazutaka Ohi,Rene L Olvera,Roel A Ophoff,Massimo Pandolfo,Tomas Paus,Zdenka Pausova,Brenda W J H Penninx,G Bruce Pike,Steven G Potkin,Bruce M Psaty,Simone Reppermund,Marcella Rietschel,Joshua L Roffman,Nina Romanczuk-Seiferth,Jerome I Rotter,Mina Ryten,Ralph L Sacco,Perminder S Sachdev,Andrew J Saykin,Reinhold Schmidt,Helena Schmidt,Peter R Schofield,Sigurdur Sigursson,Andrew Simmons,Andrew Singleton,Sanjay M Sisodiya,Colin Smith,Jordan W Smoller,Hilkka Soininen,Vidar M Steen,David J Stott,Jessika E Sussmann,Anbupalam Thalamuthu,Arthur W Toga,Bryan J Traynor,Juan Troncoso,Magda Tsolaki,Christophe Tzourio,Andre G Uitterlinden,Maria C Valdés Hernández,Marcel Van der Brug,Aad van der Lugt,Nic J A van der Wee,Neeltje E M Van Haren,Dennis van 't Ent,Marie-Jose Van Tol,Badri N Vardarajan,Bruno Vellas,Dick J Veltman,Henry Völzke,Henrik Walter,Joanna M Wardlaw,Thomas H Wassink,Michael E Weale,Daniel R Weinberger,Michael W Weiner,Wei Wen,Eric Westman,Tonya White,Tien Y Wong,Clinton B Wright,Ronald H Zielke,Alan B Zonderman,Nicholas G Martin,Cornelia M Van Duijn,Margaret J Wright,W T Longstreth,Gunter Schumann,Hans J Grabe,Barbara Franke,Lenore J Launer,Sarah E Medland,Sudha Seshadri,Paul M Thompson,M Arfan Ikram
    Source: Nature communications
  • Peptidylarginine deiminase 1-catalyzed histone citrullination is essential for early embryo development

    Friday, December 09, 2016
    Author(s): Xiaoqian Zhang,Xiaoqiu Liu,Mei Zhang,Tingting Li,Aaron Muth,Paul R Thompson,Scott A Coonrod,Xuesen Zhang
    Source: Scientific reports
  • Novel genetic loci underlying human intracranial volume identified through genome-wide association

    Tuesday, November 08, 2016
    Author(s): Hieab H H Adams,Derrek P Hibar,Vincent Chouraki,Jason L Stein,Paul A Nyquist,Miguel E Rentería,Stella Trompet,Alejandro Arias-Vasquez,Sudha Seshadri,Sylvane Desrivières,Ashley H Beecham,Neda Jahanshad,Katharina Wittfeld,Sven J Van der Lee,Lucija Abramovic,Saud Alhusaini,Najaf Amin,Micael Andersson,Konstantinos Arfanakis,Benjamin S Aribisala,Nicola J Armstrong,Lavinia Athanasiu,Tomas Axelsson,Alexa Beiser,Manon Bernard,Joshua C Bis,Laura M E Blanken,Susan H Blanton,Marc M Bohlken,Marco P Boks,Janita Bralten,Adam M Brickman,Owen Carmichael,M Mallar Chakravarty,Ganesh Chauhan,Qiang Chen,Christopher R K Ching,Gabriel Cuellar-Partida,Anouk Den Braber,Nhat Trung Doan,Stefan Ehrlich,Irina Filippi,Tian Ge,Sudheer Giddaluru,Aaron L Goldman,Rebecca F Gottesman,Corina U Greven,Oliver Grimm,Michael E Griswold,Tulio Guadalupe,Johanna Hass,Unn K Haukvik,Saima Hilal,Edith Hofer,David Hoehn,Avram J Holmes,Martine Hoogman,Deborah Janowitz,Tianye Jia,Dalia Kasperaviciute,Sungeun Kim,Marieke Klein,Bernd Kraemer,Phil H Lee,Jiemin Liao,David C M Liewald,Lorna M Lopez,Michelle Luciano,Christine Macare,Andre Marquand,Mar Matarin,Karen A Mather,Manuel Mattheisen,Bernard Mazoyer,David R McKay,Rebekah McWhirter,Yuri Milaneschi,Nazanin Mirza-Schreiber,Ryan L Muetzel,Susana Muñoz Maniega,Kwangsik Nho,Allison C Nugent,Loes M Olde Loohuis,Jaap Oosterlaan,Martina Papmeyer,Irene Pappa,Lukas Pirpamer,Sara Pudas,Benno Pütz,Kumar B Rajan,Adaikalavan Ramasamy,Jennifer S Richards,Shannon L Risacher,Roberto Roiz-Santiañez,Nanda Rommelse,Emma J Rose,Natalie A Royle,Tatjana Rundek,Philipp G Sämann,Claudia L Satizabal,Lianne Schmaal,Andrew J Schork,Li Shen,Jean Shin,Elena Shumskaya,Albert V Smith,Emma Sprooten,Lachlan T Strike,Alexander Teumer,Russell Thomson,Diana Tordesillas-Gutierrez,Roberto Toro,Daniah Trabzuni,Dhananjay Vaidya,Jeroen Van der Grond,Dennis Van der Meer,Marjolein M J Van Donkelaar,Kristel R Van Eijk,Theo G M Van Erp,Daan Van Rooij,Esther Walton,Lars T Westlye,Christopher D Whelan,Beverly G Windham,Anderson M Winkler,Girma Woldehawariat,Christiane Wolf,Thomas Wolfers,Bing Xu,Lisa R Yanek,Jingyun Yang,Alex Zijdenbos,Marcel P Zwiers,Ingrid Agartz,Neelum T Aggarwal,Laura Almasy,David Ames,Philippe Amouyel,Ole A Andreassen,Sampath Arepalli,Amelia A Assareh,Sandra Barral,Mark E Bastin,Diane M Becker,James T Becker,David A Bennett,John Blangero,Hans van Bokhoven,Dorret I Boomsma,Henry Brodaty,Rachel M Brouwer,Han G Brunner,Randy L Buckner,Jan K Buitelaar,Kazima B Bulayeva,Wiepke Cahn,Vince D Calhoun,Dara M Cannon,Gianpiero L Cavalleri,Christopher Chen,Ching-Yu Cheng,Sven Cichon,Mark R Cookson,Aiden Corvin,Benedicto Crespo-Facorro,Joanne E Curran,Michael Czisch,Anders M Dale,Gareth E Davies,Eco J C De Geus,Philip L De Jager,Greig I de Zubicaray,Norman Delanty,Chantal Depondt,Anita L DeStefano,Allissa Dillman,Srdjan Djurovic,Gary Donohoe,Wayne C Drevets,Ravi Duggirala,Thomas D Dyer,Susanne Erk,Thomas Espeseth,Denis A Evans,Iryna O Fedko,Guillén Fernández,Luigi Ferrucci,Simon E Fisher,Debra A Fleischman,Ian Ford,Tatiana M Foroud,Peter T Fox,Clyde Francks,Masaki Fukunaga,J Raphael Gibbs,David C Glahn,Randy L Gollub,Harald H H Göring,Hans J Grabe,Robert C Green,Oliver Gruber,Vilmundur Gudnason,Sebastian Guelfi,Narelle K Hansell,John Hardy,Catharina A Hartman,Ryota Hashimoto,Katrin Hegenscheid,Andreas Heinz,Stephanie Le Hellard,Dena G Hernandez,Dirk J Heslenfeld,Beng-Choon Ho,Pieter J Hoekstra,Wolfgang Hoffmann,Albert Hofman,Florian Holsboer,Georg Homuth,Norbert Hosten,Jouke-Jan Hottenga,Hilleke E Hulshoff Pol,Masashi Ikeda,M Kamran Ikram,Clifford R Jack,Mark Jenkinson,Robert Johnson,Erik G Jönsson,J Wouter Jukema,René S Kahn,Ryota Kanai,Iwona Kloszewska,David S Knopman,Peter Kochunov,John B Kwok,Stephen M Lawrie,Hervé Lemaître,Xinmin Liu,Dan L Longo,W T Longstreth,Oscar L Lopez,Simon Lovestone,Oliver Martinez,Jean-Luc Martinot,Venkata S Mattay,Colm McDonald,Andrew M McIntosh,Katie L McMahon,Francis J McMahon,Patrizia Mecocci,Ingrid Melle,Andreas Meyer-Lindenberg,Sebastian Mohnke,Grant W Montgomery,Derek W Morris,Thomas H Mosley,Thomas W Mühleisen,Bertram Müller-Myhsok,Michael A Nalls,Matthias Nauck,Thomas E Nichols,Wiro J Niessen,Markus M Nöthen,Lars Nyberg,Kazutaka Ohi,Rene L Olvera,Roel A Ophoff,Massimo Pandolfo,Tomas Paus,Zdenka Pausova,Brenda W J H Penninx,G Bruce Pike,Steven G Potkin,Bruce M Psaty,Simone Reppermund,Marcella Rietschel,Joshua L Roffman,Nina Romanczuk-Seiferth,Jerome I Rotter,Mina Ryten,Ralph L Sacco,Perminder S Sachdev,Andrew J Saykin,Reinhold Schmidt,Peter R Schofield,Sigurdur Sigurdsson,Andy Simmons,Andrew Singleton,Sanjay M Sisodiya,Colin Smith,Jordan W Smoller,Hilkka Soininen,Velandai Srikanth,Vidar M Steen,David J Stott,Jessika E Sussmann,Anbupalam Thalamuthu,Henning Tiemeier,Arthur W Toga,Bryan J Traynor,Juan Troncoso,Jessica A Turner,Christophe Tzourio,Andre G Uitterlinden,Maria C Valdés Hernández,Marcel Van der Brug,Aad Van der Lugt,Nic J A Van der Wee,Cornelia M Van Duijn,Neeltje E M Van Haren,Dennis Van T Ent,Marie-Jose Van Tol,Badri N Vardarajan,Dick J Veltman,Meike W Vernooij,Henry Völzke,Henrik Walter,Joanna M Wardlaw,Thomas H Wassink,Michael E Weale,Daniel R Weinberger,Michael W Weiner,Wei Wen,Eric Westman,Tonya White,Tien Y Wong,Clinton B Wright,H Ronald Zielke,Alan B Zonderman,Ian J Deary,Charles DeCarli,Helena Schmidt,Nicholas G Martin,Anton J M De Craen,Margaret J Wright,Lenore J Launer,Gunter Schumann,Myriam Fornage,Barbara Franke,Stéphanie Debette,Sarah E Medland,M Arfan Ikram,Paul M Thompson
    Source: Nature neuroscience
  • A molecular signature of preclinical rheumatoid arthritis triggered by dysregulated PTPN22

    Wednesday, October 26, 2016
    Author(s): Hui-Hsin Chang,Guang-Yaw Liu,Nishant Dwivedi,Bo Sun,Yuko Okamoto,Jennifer D Kinslow,Kevin D Deane,M Kristen Demoruelle,Jill M Norris,Paul R Thompson,Jeffrey A Sparks,Deepak A Rao,Elizabeth W Karlson,Hui-Chih Hung,V Michael Holers,I-Cheng Ho
    Source: JCI insight
  • Human subcortical brain asymmetries in 15,847 people worldwide reveal effects of age and sex

    Saturday, October 15, 2016
    Author(s): Tulio Guadalupe,Samuel R Mathias,Theo G M vanErp,Christopher D Whelan,Marcel P Zwiers,Yoshinari Abe,Lucija Abramovic,Ingrid Agartz,Ole A Andreassen,Alejandro Arias-Vásquez,Benjamin S Aribisala,Nicola J Armstrong,Volker Arolt,Eric Artiges,Rosa Ayesa-Arriola,Vatche G Baboyan,Tobias Banaschewski,Gareth Barker,Mark E Bastin,Bernhard T Baune,John Blangero,Arun L W Bokde,Premika S W Boedhoe,Anushree Bose,Silvia Brem,Henry Brodaty,Uli Bromberg,Samantha Brooks,Christian Büchel,Jan Buitelaar,Vince D Calhoun,Dara M Cannon,Anna Cattrell,Yuqi Cheng,Patricia J Conrod,Annette Conzelmann,Aiden Corvin,Benedicto Crespo-Facorro,Fabrice Crivello,Udo Dannlowski,Greig I de Zubicaray,Sonja M C de Zwarte,Ian J Deary,Sylvane Desrivières,Nhat Trung Doan,Gary Donohoe,Erlend S Dørum,Stefan Ehrlich,Thomas Espeseth,Guillén Fernández,Herta Flor,Jean-Paul Fouche,Vincent Frouin,Masaki Fukunaga,Jürgen Gallinat,Hugh Garavan,Michael Gill,Andrea Gonzalez Suarez,Penny Gowland,Hans J Grabe,Dominik Grotegerd,Oliver Gruber,Saskia Hagenaars,Ryota Hashimoto,Tobias U Hauser,Andreas Heinz,Derrek P Hibar,Pieter J Hoekstra,Martine Hoogman,Fleur M Howells,Hao Hu,Hilleke E Hulshoff Pol,Chaim Huyser,Bernd Ittermann,Neda Jahanshad,Erik G Jönsson,Sarah Jurk,Rene S Kahn,Sinead Kelly,Bernd Kraemer,Harald Kugel,Jun Soo Kwon,Herve Lemaitre,Klaus-Peter Lesch,Christine Lochner,Michelle Luciano,Andre F Marquand,Nicholas G Martin,Ignacio Martínez-Zalacaín,Jean-Luc Martinot,David Mataix-Cols,Karen Mather,Colm McDonald,Katie L McMahon,Sarah E Medland,José M Menchón,Derek W Morris,Omar Mothersill,Susana Munoz Maniega,Benson Mwangi,Takashi Nakamae,Tomohiro Nakao,Janardhanan C Narayanaswaamy,Frauke Nees,Jan E Nordvik,A Marten H Onnink,Nils Opel,Roel Ophoff,Marie-Laure Paillère Martinot,Dimitri Papadopoulos Orfanos,Paul Pauli,Tomáš Paus,Luise Poustka,Janardhan Yc Reddy,Miguel E Renteria,Roberto Roiz-Santiáñez,Annerine Roos,Natalie A Royle,Perminder Sachdev,Pascual Sánchez-Juan,Lianne Schmaal,Gunter Schumann,Elena Shumskaya,Michael N Smolka,Jair C Soares,Carles Soriano-Mas,Dan J Stein,Lachlan T Strike,Roberto Toro,Jessica A Turner,Nathalie Tzourio-Mazoyer,Anne Uhlmann,Maria Valdés Hernández,Odile A van den Heuvel,Dennis van der Meer,Neeltje E M van Haren,Dick J Veltman,Ganesan Venkatasubramanian,Nora C Vetter,Daniella Vuletic,Susanne Walitza,Henrik Walter,Esther Walton,Zhen Wang,Joanna Wardlaw,Wei Wen,Lars T Westlye,Robert Whelan,Katharina Wittfeld,Thomas Wolfers,Margaret J Wright,Jian Xu,Xiufeng Xu,Je-Yeon Yun,JingJing Zhao,Barbara Franke,Paul M Thompson,David C Glahn,Bernard Mazoyer,Simon E Fisher,Clyde Francks
    Source: Brain imaging and behavior
  • GnRH Stimulates Peptidylarginine Deiminase Catalyzed Histone Citrullination in Gonadotrope Cells

    Thursday, September 08, 2016
    Author(s): Shaihla A Khan,Brian S Edwards,Aaron Muth,Paul R Thompson,Brian D Cherrington,Amy M Navratil
    Source: Molecular endocrinology (Baltimore, Md.)
  • Neutrophil extracellular traps exacerbate Th1-mediated autoimmune responses in rheumatoid arthritis by promoting DC maturation

    Saturday, September 03, 2016
    Author(s): Garyfalia Papadaki,Konstantinos Kambas,Christiana Choulaki,Katerina Vlachou,Elias Drakos,George Bertsias,Konstantinos Ritis,Dimitrios T Boumpas,Paul R Thompson,Panayotis Verginis,Prodromos Sidiropoulos
    Source: European journal of immunology
  • Tumor necrosis factor alpha, citrullination, and peptidylarginine deiminase 4 in lung and joint inflammation

    Monday, July 25, 2016
    Author(s): Mandar Bawadekar,Annette Gendron-Fitzpatrick,Ryan Rebernick,Daeun Shim,Thomas F Warner,Anthony P Nicholas,Lennart K A Lundblad,Paul R Thompson,Miriam A Shelef
    Source: Arthritis research & therapy
  • Nicotine induces neutrophil extracellular traps

    Saturday, June 18, 2016
    Author(s): Ava Hosseinzadeh,Paul R Thompson,Brahm H Segal,Constantin F Urban
    Source: Journal of leukocyte biology
  • Abrogation of collagen-induced arthritis by a peptidyl arginine deiminase inhibitor is associated with modulation of T cell-mediated immune responses

    Tuesday, May 24, 2016
    Author(s): Joanna Kawalkowska,Anne-Marie Quirke,Fatemeh Ghari,Simon Davis,Venkataraman Subramanian,Paul R Thompson,Richard O Williams,Roman Fischer,Nicholas B La Thangue,Patrick J Venables
    Source: Scientific reports
  • Peptidylarginine Deiminase 3 (PAD3) Is Upregulated by Prolactin Stimulation of CID-9 Cells and Expressed in the Lactating Mouse Mammary Gland

    Saturday, January 23, 2016
    Author(s): Guangyuan Li,Isaac N Hayward,Brittany R Jenkins,Heather M Rothfuss,Coleman H Young,Marja T Nevalainen,Aaron Muth,Paul R Thompson,Amy M Navratil,Brian D Cherrington
    Source: PloS one
  • Protein Arginine Methylation and Citrullination in Epigenetic Regulation

    Tuesday, December 22, 2015
    Author(s): Jakob Fuhrmann,Paul R Thompson
    Source: ACS chemical biology
  • Detection and identification of protein citrullination in complex biological systems

    Saturday, October 31, 2015
    Author(s): Kathleen W Clancy,Eranthie Weerapana,Paul R Thompson
    Source: Current opinion in chemical biology
  • Molecular targeting of protein arginine deiminases to suppress colitis and prevent colon cancer

    Wednesday, October 07, 2015
    Author(s): Erin E Witalison,Xiangli Cui,Corey P Causey,Paul R Thompson,Lorne J Hofseth
    Source: Oncotarget
  • Chemical Proteomic Platform To Identify Citrullinated Proteins

    Saturday, September 12, 2015
    Author(s): Daniel M Lewallen,Kevin L Bicker,Venkataraman Subramanian,Kathleen W Clancy,Daniel J Slade,Julianne Martell,Christina J Dreyton,Jeremy Sokolove,Eranthie Weerapana,Paul R Thompson
    Source: ACS chemical biology
  • Utilization of the Soft Agar Colony Formation Assay to Identify Inhibitors of Tumorigenicity in Breast Cancer Cells

    Saturday, June 13, 2015
    Author(s): Sachi Horibata,Tommy V Vo,Venkataraman Subramanian,Paul R Thompson,Scott A Coonrod
    Source: Journal of visualized experiments : JoVE
  • Inhibiting protein arginine deiminases has antioxidant consequences

    Saturday, January 31, 2015
    Author(s): Erin E Witalison,Xiangli Cui,Anne B Hofseth,Venkataraman Subramanian,Corey P Causey,Paul R Thompson,Lorne J Hofseth
    Source: The Journal of pharmacology and experimental therapeutics
  • Protein arginine deiminase 2 binds calcium in an ordered fashion: implications for inhibitor design

    Tuesday, January 27, 2015
    Author(s): Daniel J Slade,Pengfei Fang,Christina J Dreyton,Ying Zhang,Jakob Fuhrmann,Don Rempel,Benjamin D Bax,Scott A Coonrod,Huw D Lewis,Min Guo,Michael L Gross,Paul R Thompson
    Source: ACS chemical biology
  • Common genetic variants influence human subcortical brain structures

    Thursday, January 22, 2015
    Author(s): Derrek P Hibar,Jason L Stein,Miguel E Renteria,Alejandro Arias-Vasquez,Sylvane Desrivières,Neda Jahanshad,Roberto Toro,Katharina Wittfeld,Lucija Abramovic,Micael Andersson,Benjamin S Aribisala,Nicola J Armstrong,Manon Bernard,Marc M Bohlken,Marco P Boks,Janita Bralten,Andrew A Brown,M Mallar Chakravarty,Qiang Chen,Christopher R K Ching,Gabriel Cuellar-Partida,Anouk den Braber,Sudheer Giddaluru,Aaron L Goldman,Oliver Grimm,Tulio Guadalupe,Johanna Hass,Girma Woldehawariat,Avram J Holmes,Martine Hoogman,Deborah Janowitz,Tianye Jia,Sungeun Kim,Marieke Klein,Bernd Kraemer,Phil H Lee,Loes M Olde Loohuis,Michelle Luciano,Christine Macare,Karen A Mather,Manuel Mattheisen,Yuri Milaneschi,Kwangsik Nho,Martina Papmeyer,Adaikalavan Ramasamy,Shannon L Risacher,Roberto Roiz-Santiañez,Emma J Rose,Alireza Salami,Philipp G Sämann,Lianne Schmaal,Andrew J Schork,Jean Shin,Lachlan T Strike,Alexander Teumer,Marjolein M J van Donkelaar,Kristel R van Eijk,Raymond K Walters,Lars T Westlye,Christopher D Whelan,Anderson M Winkler,Marcel P Zwiers,Saud Alhusaini,Lavinia Athanasiu,Stefan Ehrlich,Marina M H Hakobjan,Cecilie B Hartberg,Unn K Haukvik,Angelien J G A M Heister,David Hoehn,Dalia Kasperaviciute,David C M Liewald,Lorna M Lopez,Remco R R Makkinje,Mar Matarin,Marlies A M Naber,D Reese McKay,Margaret Needham,Allison C Nugent,Benno Pütz,Natalie A Royle,Li Shen,Emma Sprooten,Daniah Trabzuni,Saskia S L van der Marel,Kimm J E van Hulzen,Esther Walton,Christiane Wolf,Laura Almasy,David Ames,Sampath Arepalli,Amelia A Assareh,Mark E Bastin,Henry Brodaty,Kazima B Bulayeva,Melanie A Carless,Sven Cichon,Aiden Corvin,Joanne E Curran,Michael Czisch,Greig I de Zubicaray,Allissa Dillman,Ravi Duggirala,Thomas D Dyer,Susanne Erk,Iryna O Fedko,Luigi Ferrucci,Tatiana M Foroud,Peter T Fox,Masaki Fukunaga,J Raphael Gibbs,Harald H H Göring,Robert C Green,Sebastian Guelfi,Narelle K Hansell,Catharina A Hartman,Katrin Hegenscheid,Andreas Heinz,Dena G Hernandez,Dirk J Heslenfeld,Pieter J Hoekstra,Florian Holsboer,Georg Homuth,Jouke-Jan Hottenga,Masashi Ikeda,Clifford R Jack,Mark Jenkinson,Robert Johnson,Ryota Kanai,Maria Keil,Jack W Kent,Peter Kochunov,John B Kwok,Stephen M Lawrie,Xinmin Liu,Dan L Longo,Katie L McMahon,Eva Meisenzahl,Ingrid Melle,Sebastian Mohnke,Grant W Montgomery,Jeanette C Mostert,Thomas W Mühleisen,Michael A Nalls,Thomas E Nichols,Lars G Nilsson,Markus M Nöthen,Kazutaka Ohi,Rene L Olvera,Rocio Perez-Iglesias,G Bruce Pike,Steven G Potkin,Ivar Reinvang,Simone Reppermund,Marcella Rietschel,Nina Romanczuk-Seiferth,Glenn D Rosen,Dan Rujescu,Knut Schnell,Peter R Schofield,Colin Smith,Vidar M Steen,Jessika E Sussmann,Anbupalam Thalamuthu,Arthur W Toga,Bryan J Traynor,Juan Troncoso,Jessica A Turner,Maria C Valdés Hernández,Dennis van 't Ent,Marcel van der Brug,Nic J A van der Wee,Marie-Jose van Tol,Dick J Veltman,Thomas H Wassink,Eric Westman,Ronald H Zielke,Alan B Zonderman,David G Ashbrook,Reinmar Hager,Lu Lu,Francis J McMahon,Derek W Morris,Robert W Williams,Han G Brunner,Randy L Buckner,Jan K Buitelaar,Wiepke Cahn,Vince D Calhoun,Gianpiero L Cavalleri,Benedicto Crespo-Facorro,Anders M Dale,Gareth E Davies,Norman Delanty,Chantal Depondt,Srdjan Djurovic,Wayne C Drevets,Thomas Espeseth,Randy L Gollub,Beng-Choon Ho,Wolfgang Hoffmann,Norbert Hosten,René S Kahn,Stephanie Le Hellard,Andreas Meyer-Lindenberg,Bertram Müller-Myhsok,Matthias Nauck,Lars Nyberg,Massimo Pandolfo,Brenda W J H Penninx,Joshua L Roffman,Sanjay M Sisodiya,Jordan W Smoller,Hans van Bokhoven,Neeltje E M van Haren,Henry Völzke,Henrik Walter,Michael W Weiner,Wei Wen,Tonya White,Ingrid Agartz,Ole A Andreassen,John Blangero,Dorret I Boomsma,Rachel M Brouwer,Dara M Cannon,Mark R Cookson,Eco J C de Geus,Ian J Deary,Gary Donohoe,Guillén Fernández,Simon E Fisher,Clyde Francks,David C Glahn,Hans J Grabe,Oliver Gruber,John Hardy,Ryota Hashimoto,Hilleke E Hulshoff Pol,Erik G Jönsson,Iwona Kloszewska,Simon Lovestone,Venkata S Mattay,Patrizia Mecocci,Colm McDonald,Andrew M McIntosh,Roel A Ophoff,Tomas Paus,Zdenka Pausova,Mina Ryten,Perminder S Sachdev,Andrew J Saykin,Andy Simmons,Andrew Singleton,Hilkka Soininen,Joanna M Wardlaw,Michael E Weale,Daniel R Weinberger,Hieab H H Adams,Lenore J Launer,Stephan Seiler,Reinhold Schmidt,Ganesh Chauhan,Claudia L Satizabal,James T Becker,Lisa Yanek,Sven J van der Lee,Maritza Ebling,Bruce Fischl,W T Longstreth,Douglas Greve,Helena Schmidt,Paul Nyquist,Louis N Vinke,Cornelia M van Duijn,Luting Xue,Bernard Mazoyer,Joshua C Bis,Vilmundur Gudnason,Sudha Seshadri,M Arfan Ikram,Alzheimer’s Disease Neuroimaging Initiative,CHARGE Consortium,EPIGEN,IMAGEN,SYS,Nicholas G Martin,Margaret J Wright,Gunter Schumann,Barbara Franke,Paul M Thompson,Sarah E Medland
    Source: Nature
  • Design, synthesis, and biological evaluation of tetrazole analogs of Cl-amidine as protein arginine deiminase inhibitors

    Wednesday, January 07, 2015
    Author(s): Venkataraman Subramanian,Jason S Knight,Sangram Parelkar,Lynne Anguish,Scott A Coonrod,Mariana J Kaplan,Paul R Thompson
    Source: Journal of medicinal chemistry