Latest News
May 23, 2024
Video: Renegade Research/Remission Biome Roundtable (video here)
Topic: T-cell dysfunction in ME/CFS and Long Covid
Speakers: Liisa K. Selin, MD PhD; Anna Gil, PhD, viral immunologists from the University of Massachusetts Chan Medical School; Roshan Kumar, PhD, Executive Director, External Innovation, HiFiBiO Therapeutics; and Megan Fitzgerald and Rivka Solomon, Patient-Led Research Collaborative (PLRC) patient representatives with the above two labs.
About: More on the HiFiBiO-Selin Lab collaboration found here and here.
April 16, 2024
Press release by HiFiBiO regarding Selin Lab Collaboration
HiFiBiO Therapeutics Receives Grant to Research Long COVID and ME/CFS in Collaboration with UMass Chan Medical School
February 1, 2024
UMass Chan Medical School News (magazine article)
UMass Chan advances research into long COVID, myalgic encephalomyelitis
October 10, 2023
Press release by PLRC Fund: The Patient-Led Research Fund is a $5 million fund that provided grants to Long COVID biomedical research projects, awarded by a panel of patient-researchers with expertise in post-viral illnesses and lived experience of Long COVID and/or ME/CFS: "Immune repertoire profiling of Long COVID and ME/CFS patients – Dr. Roshan Kumar, HiFiBiO Therapeutics; Dr. Liisa Selin and Dr. Anna Gil, University of Massachusetts Chan Medical School. "Multiple lines of evidence point to underlying immune abnormalities in patients with infection-associated chronic illnesses such as Long COVID and myalgic encephalomyelitis/chronic fatigue syndrome (ME/CFS). However, how these abnormalities relate to disease symptoms and mechanisms is unclear…In this project, novel single-cell profiling technologies will be applied through the DIS® platform to characterize immune repertoires and identify targets of B and T cell responses in ME/CFS and Long COVID patients. By identifying autoantigens and viral targets of these immune responses, there will be insight into underlying disease mechanisms defining patient subgroups that can be translated into diagnostic biomarkers and therapeutic interventions.”
November 2022
PLRC grant awarded to Selin Lab: "Altered T cell responses in Long COVID (PASC) and ME/CFS – Dr. Liisa Selin and Dr. Anna Gil, University of Massachusetts Chan Medical School: "Based on earlier research, this project hypothesizes that the common theme in Long COVID and ME/CFS is an aberrant response to an immunological trigger like infection that results in a permanently dysregulated immune system as a result of CD8 T cell exhaustion. This project will do a deep dive into the T cells of Long COVID and ME/CFS patients, looking for exhausted and activated subsets, and will additionally look at reactivated herpesviruses in relation to these findings.
November 23, 2022
Solve Ramsay Grant Scientists Among Those Awarded Nearly $5 Million for Biomedical Research: "This week the Patient-Led Research Collaborative (PLRC) announced $4.8 million in biomedical research awards for Long Covid and associated conditions."
October 5, 2022
WBUR, Boston's National Public Radio station
How Chronic Fatigue Syndrome is helping doctors understand long COVID
August 8, 2022
WBUR, Boston's National Public Radio station (article and accompanying radio piece).To solve the mystery of long COVID, researchers look to an older disease Priyanka Dayal McCluskey, senior health reporter for Boston's highly regarded National Public Radio station, WBUR, featured Dr. Selin in her story on Long Covid and ME/CFS research.
June 16, 2022
June 9, 2022
U.S. Congressmen Visit ME/CFS/Long Covid Researchers at UMass Chan Medical School:
Congressmen Jim McGovern (D-MA) and Jamie Raskin (D-MD) visited researchers studying ME/CFS and Long COVID at the UMass Chan Medical School in Worcester, MA.
November 17, 2021
Dr. Amy Proal interviews Dr. Liisa Selin about T cell exhaustion and viral activity in ME/CFS
November 3, 3021
UMass Chan Medical School News (magazine article)
Liisa Selin and Anna Gil study links between viral infections and ME/CFS: NIH grant to study T cell function after viral illnesses may have implications for long COVID
March 16, 2021
Press release from Massachusetts ME/CFS & FM Association: NIH grant awarded to the Selin Lab: "This NIH RO1 grant, titled “Altered T cell Responses in ME/CFS” allows the researchers to examine the role of aberrant T cell responses in the immunopathogenesis of ME/CFS patients. Selin and Gil's recent research findings could point to potential biomarkers, treatments and ways of tracking response to therapy for the disease, things that have been sorely missing."
September 27, 2020
Video from MassME Research Club: Speakers Liisa Selin, MD, PhD, and Anna Gil, PhD
2020
December 5, 2017
Researchers connect severity of 'kissing disease' to T-cell population
November 23, 2005
Press release from UMass Medical School: "Immunological karma: T cells reactive to old flu infections make unrelated viral infections worse."