Optical Animal Imaging Facility
INSTRUMENTS
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IVIS-100 (Perkin-Elmer) |
IVIS Spectrum CT (Perkin-Elmer) |
Vevo 3100 Ultrasound (FujiFilm VisualSonics) |
Both IVIS cameras detect bioluminescence and fluorescence contained within solutions, petri dishes, culture plates, cells or live animals.
The IVIS-100 has 4 excitation/emission fluorescent filters, covers the excitation range of 445-750 nm and emission of 500-875 nm. The chamber holds 1-5 mice or 1-3 rats in a single view. Acquisition time is about 1-3 minutes; therefore, useful for high-throughput screening. The system provides 2D imaging with photo overlay and quantification of the surface radiance of the source.
The IVIS Spectrum CT has 10 excitation and 18 emission fluorescent filters, along with spectral unmixing to facilitate the use of multiple reporters within the same subject. The system provides both 2D and 3D imaging. The 3D aspect calculates the X,Y,Z location and brightness of the source in the subject interior, and quantifies a depth corrected signal intensity. CT registration provides anatomical registration with signal at depth.
Each camera is equipped with a gaseous anesthesia vaporizer. Oxygen and isoflurane are provided.
New Vevo 3100 High Resolution Ultrasound System (VisualSonics) for small animal models
The instrument is available to investigators through the Optical Core. It can be used for general organ imaging and cancer models.
Applications include:
- Image guided needle injection
- perfusion tracking
- reproductive health evaluation
- organ 3D volume
- tumor verification and sizing
To learn how to get started and to arrange training contact Mary Rusckowski.
LOCATION
You must have pre-authorization to make a reservation, please contact the core to obtain access. If you are authorized, click below to make your reservation.
IVIS-100: Animal Facility, A-level, Room SA-443 - Click to Reserve
IVIS Spectrum CT: Animal Facility, A-level, Room SA-414 - Click to Reserve
Vevo 3100 Ultrasound: Animal Facility, A-level, Room SA-414 - Click to Reserve
FEES
Charges are per hour (invoiced through the Research Cores Office) and are based on time reserved in the on-line calendar and in-room record log book of arrival and departure times.
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Instrument |
Internal Unassisted |
Internal Assisted |
Outside Academic Assisted |
External Industry Core operated |
|
IVIS-100 |
$55 |
$182 |
$208 |
$236 |
|
IVIS Spectrum CT |
$68 |
$210 |
$236 |
$289 |
|
Vevo 3100 Ultrasound |
$79 |
$215 |
$247 |
$299 |
Effective March 1, 2019 there is a 1 hour minimum charge for reservations. Reservations cancelled must be done 24 hours in advance.
If you are interested in using the Optical Camera, please contact:
Director, Mary Rusckowski, Ph.D.
Department of Radiology, S6-315
Mary.Rusckowski@umassmed.edu
508-856-6972