Publications 2019
Allen TM, Brehm MA, Bridges S, Ferguson S, Kumar P, Mirochnitchenko O, Palucka K, Pelanda R, Sanders-Beer B, Shultz LD, Su L, PrabhuDas M. Humanized immune system mouse models: progress, challenges and opportunities. Nat Immunol. 2019;20(7):770-4. Epub 2019/06/05. doi: 10.1038/s41590-019-0416-z. PubMed PMID: 31160798.
https://www.ncbi.nlm.nih.gov/pubmed/31160798
Alterman JF, Godinho B, Hassler MR, Ferguson CM, Echeverria D, Sapp E, Haraszti RA, Coles AH, Conroy F, Miller R, Roux L, Yan P, Knox EG, Turanov AA, King RM, Gernoux G, Mueller C, Gray-Edwards HL, Moser RP, Bishop NC, Jaber SM, Gounis MJ, Sena-Esteves M, Pai AA, DiFiglia M, Aronin N, Khvorova A. A divalent siRNA chemical scaffold for potent and sustained modulation of gene expression throughout the central nervous system. Nat Biotechnol. 2019;37(8):884-94. Epub 2019/08/04. doi: 10.1038/s41587-019-0205-0. PubMed PMID: 31375812; PMCID: PMC6879195.
https://www.ncbi.nlm.nih.gov/pubmed/31375812
Batista TM, Garcia-Martin R, Cai W, Konishi M, O'Neill BT, Sakaguchi M, Kim JH, Jung DY, Kim JK, Kahn CR. Multi-dimensional Transcriptional Remodeling by Physiological Insulin In Vivo. Cell Rep. 2019;26(12):3429-43 e3. Epub 2019/03/21. doi: 10.1016/j.celrep.2019.02.081. PubMed PMID: 30893613; PMCID: PMC6543850. https://www.ncbi.nlm.nih.gov/pubmed/30893613
Beichman AC, Koepfli KP, Li G, Murphy W, Dobrynin P, Kliver S, Tinker MT, Murray MJ, Johnson J, Lindblad-Toh K, Karlsson EK, Lohmueller KE, Wayne RK. Aquatic Adaptation and Depleted Diversity: A Deep Dive into the Genomes of the Sea Otter and Giant Otter. Mol Biol Evol. 2019;36(12):2631-55. Epub 2019/06/19. doi: 10.1093/molbev/msz101. PubMed PMID: 31212313.
https://www.ncbi.nlm.nih.gov/pubmed/31212313
Biscans A, Coles A, Echeverria D, Khvorova A. The valency of fatty acid conjugates impacts siRNA pharmacokinetics, distribution, and efficacy in vivo. J Control Release. 2019;302:116-25. Epub 2019/04/04. doi: 10.1016/j.jconrel.2019.03.028. PubMed PMID: 30940496; PMCID: PMC6546539. https://www.ncbi.nlm.nih.gov/pubmed/30940496
Biscans A, Coles A, Haraszti R, Echeverria D, Hassler M, Osborn M, Khvorova A. Diverse lipid conjugates for functional extra-hepatic siRNA delivery in vivo. Nucleic Acids Res. 2019;47(3):1082-96. Epub 2018/12/14. doi: 10.1093/nar/gky1239. PubMed PMID: 30544191; PMCID: PMC6379722.
https://www.ncbi.nlm.nih.gov/pubmed/30544191
Blaszczak AM, Wright VP, Anandani K, Liu J, Jalilvand A, Bergin S, Nicoloro SM, Czech MP, Lafuse W, Deng T, Bradley D, Hsueh WA. Loss of Antigen Presentation in Adipose Tissue Macrophages or in Adipocytes, but Not Both, Improves Glucose Metabolism. J Immunol. 2019;202(8):2451-9. Epub 2019/03/10. doi: 10.4049/jimmunol.1801470. PubMed PMID: 30850480.
https://www.ncbi.nlm.nih.gov/pubmed/30850480
Boucher JI, Whitfield TW, Dauphin A, Nachum G, Hollins C, Zeldovich KB, Swanstrom R, Schiffer CA, Luban J, Bolon DNA. Constrained Mutational Sampling of Amino Acids in HIV-1 Protease Evolution. Mol Biol Evol. 2019;36(4):798-810. Epub 2019/02/06. doi: 10.1093/molbev/msz022. PubMed PMID: 30721995. https://www.ncbi.nlm.nih.gov/pubmed/30721995
Braun MC, Castillo-Ruiz A, Indic P, Jung DY, Kim JK, Brown RH, Jr., Swoap SJ, Schwartz WJ. Defective daily temperature regulation in a mouse model of amyotrophic lateral sclerosis. Exp Neurol. 2019;311:305-12. Epub 2018/07/22. doi: 10.1016/j.expneurol.2018.07.008. PubMed PMID: 30031021; PMCID: PMC6263852. https://www.ncbi.nlm.nih.gov/pubmed/30031021
Bulcha JT, Giese GE, Ali MZ, Lee YU, Walker MD, Holdorf AD, Yilmaz LS, Brewster RC, Walhout AJM. A Persistence Detector for Metabolic Network Rewiring in an Animal. Cell Rep. 2019;26(2):460-8 e4. Epub 2019/01/10. doi: 10.1016/j.celrep.2018.12.064. PubMed PMID: 30625328; PMCID: PMC6368391. https://www.ncbi.nlm.nih.gov/pubmed/30625328
Carreiro S, Marvel-Coen J, Lee R, Chapman B, Ambros V. Circulating microRNA Profiles in Acetaminophen Toxicity. J Med Toxicol. 2019. Epub 2019/12/04. doi: 10.1007/s13181-019-00739-6. PubMed PMID: 31792846.
https://www.ncbi.nlm.nih.gov/pubmed/31792846
Casewell NR, Petras D, Card DC, Suranse V, Mychajliw AM, Richards D, Koludarov I, Albulescu LO, Slagboom J, Hempel BF, Ngum NM, Kennerley RJ, Brocca JL, Whiteley G, Harrison RA, Bolton FMS, Debono J, Vonk FJ, Alfoldi J, Johnson J, Karlsson EK, Lindblad-Toh K, Mellor IR, Sussmuth RD, Fry BG, Kuruppu S, Hodgson WC, Kool J, Castoe TA, Barnes I, Sunagar K, Undheim EAB, Turvey ST. Solenodon genome reveals convergent evolution of venom in eulipotyphlan mammals. Proc Natl Acad Sci U S A. 2019;116(51):25745-55. Epub 2019/11/28. doi: 10.1073/pnas.1906117116. PubMed PMID: 31772017; PMCID: PMC6926037. https://www.ncbi.nlm.nih.gov/pubmed/31772017
Charuchaibovorn S, Sanprasert V, Sutthanont N, Hu Y, Abraham A, Ostroff GR, Aroian RV, Jaleta TG, Lok JB, Nuchprayoon S. Bacillus thuringiensis Cry5B is Active against Strongyloides stercoralis in vitro. Am J Trop Med Hyg. 2019;101(5):1177-82. Epub 2019/09/14. doi: 10.4269/ajtmh.19-0083. PubMed PMID: 31516117; PMCID: PMC6838580.
https://www.ncbi.nlm.nih.gov/pubmed/31516117
Chiramel AI, Meyerson NR, McNally KL, Broeckel RM, Montoya VR, Mendez-Solis O, Robertson SJ, Sturdevant GL, Lubick KJ, Nair V, Youseff BH, Ireland RM, Bosio CM, Kim K, Luban J, Hirsch VM, Taylor RT, Bouamr F, Sawyer SL, Best SM. TRIM5alpha Restricts Flavivirus Replication by Targeting the Viral Protease for Proteasomal Degradation. Cell Rep. 2019;27(11):3269-83 e6. Epub 2019/06/13. doi: 10.1016/j.celrep.2019.05.040. PubMed PMID: 31189110.
https://www.ncbi.nlm.nih.gov/pubmed/31189110
Choi S, Ambros V. The C. elegans heterochronic gene lin-28 coordinates the timing of hypodermal and somatic gonadal programs for hermaphrodite reproductive system morphogenesis. Development. 2019;146(5). Epub 2019/02/13. doi: 10.1242/dev.164293. PubMed PMID: 30745431; PMCID: PMC6432661. https://www.ncbi.nlm.nih.gov/pubmed/30745431
Chowdhury M, Li CF, He Z, Lu Y, Liu XS, Wang YF, Ip YT, Strand MR, Yu XQ. Toll family members bind multiple Spatzle proteins and activate antimicrobial peptide gene expression in Drosophila. J Biol Chem. 2019;294(26):10172-81. Epub 2019/05/16. doi: 10.1074/jbc.RA118.006804. PubMed PMID: 31088910.
https://www.ncbi.nlm.nih.gov/pubmed/31088910
D'Agostino L, Nie Y, Goswami S, Tong K, Yu S, Bandyopadhyay S, Flores J, Zhang X, Balasubramanian I, Joseph I, Sakamori R, Farrell V, Li Q, Yang CS, Gao B, Ferraris RP, Yehia G, Bonder EM, Goldenring JR, Verzi MP, Zhang L, Ip YT, Gao N. Recycling Endosomes in Mature Epithelia Restrain Tumorigenic Signaling. Cancer Res. 2019;79(16):4099-112. Epub 2019/06/27. doi: 10.1158/0008-5472.CAN-18-4075. PubMed PMID: 31239271; PMCID: PMC6726494.
https://www.ncbi.nlm.nih.gov/pubmed/31239271
Dahan O, Dorfman BS, Sayin S, Rosener B, Hua T, Yarden A, Mitchell A. Harnessing robotic automation and web-based technologies to modernize scientific outreach. PLoS Biol. 2019;17(6):e3000348. Epub 2019/06/27. doi: 10.1371/journal.pbio.3000348. PubMed PMID: 31242174.
https://www.ncbi.nlm.nih.gov/pubmed/31242174
Das S, Malaby AW, Nawrotek A, Zhang W, Zeghouf M, Maslen S, Skehel M, Chakravarthy S, Irving TC, Bilsel O, Cherfils J, Lambright DG. Structural Organization and Dynamics of Homodimeric Cytohesin Family Arf GTPase Exchange Factors in Solution and on Membranes. Structure. 2019;27(12):1782-97 e7. Epub 2019/10/12. doi: 10.1016/j.str.2019.09.007. PubMed PMID: 31601460; PMCID: PMC6948192.
https://www.ncbi.nlm.nih.gov/pubmed/31601460
Dittmann A, Kennedy NJ, Soltero NL, Morshed N, Mana MD, Yilmaz OH, Davis RJ, White FM. High-fat diet in a mouse insulin-resistant model induces widespread rewiring of the phosphotyrosine signaling network. Mol Syst Biol. 2019;15(8):e8849. Epub 2019/08/30. doi: 10.15252/msb.20198849. PubMed PMID: 31464373; PMCID: PMC6674232.
https://www.ncbi.nlm.nih.gov/pubmed/31464373
Duan J, Lambright DG. TRAPPing a Rab GTPase by the Tail. Dev Cell. 2019;48(1):9-11. Epub 2019/01/09. doi: 10.1016/j.devcel.2018.12.008. PubMed PMID: 30620905. https://www.ncbi.nlm.nih.gov/pubmed/30620905
Dumas SN, Guo CA, Kim JK, Friedline RH, Ntambi JM. Interleukin-6 derived from cutaneous deficiency of stearoyl-CoA desaturase- 1 may mediate metabolic organ crosstalk among skin, adipose tissue and liver. Biochem Biophys Res Commun. 2019;508(1):87-91. Epub 2018/11/25. doi: 10.1016/j.bbrc.2018.11.083. PubMed PMID: 30470572; PMCID: PMC6309575.
https://www.ncbi.nlm.nih.gov/pubmed/30470572
Edraki A, Mir A, Ibraheim R, Gainetdinov I, Yoon Y, Song CQ, Cao Y, Gallant J, Xue W, Rivera-Perez JA, Sontheimer EJ. A Compact, High-Accuracy Cas9 with a Dinucleotide PAM for In Vivo Genome Editing. Mol Cell. 2019;73(4):714-26 e4. Epub 2018/12/26. doi: 10.1016/j.molcel.2018.12.003. PubMed PMID: 30581144; PMCID: PMC6386616.
https://www.ncbi.nlm.nih.gov/pubmed/30581144
Ehrhardt N, Cui J, Dagdeviren S, Saengnipanthkul S, Goodridge HS, Kim JK, Lantier L, Guo X, Chen YI, Raffel LJ, Buchanan TA, Hsueh WA, Rotter JI, Goodarzi MO, Peterfy M. Adiposity-Independent Effects of Aging on Insulin Sensitivity and Clearance in Mice and Humans. Obesity (Silver Spring). 2019;27(3):434-43. Epub 2019/02/26. doi: 10.1002/oby.22418. PubMed PMID: 30801985; PMCID: PMC6474357.
https://www.ncbi.nlm.nih.gov/pubmed/30801985
Elaimy AL, Amante JJ, Zhu LJ, Wang M, Walmsley CS, FitzGerald TJ, Goel HL, Mercurio AM. The VEGF receptor neuropilin 2 promotes homologous recombination by stimulating YAP/TAZ-mediated Rad51 expression. Proc Natl Acad Sci U S A. 2019;116(28):14174-80. Epub 2019/06/27. doi: 10.1073/pnas.1821194116. PubMed PMID: 31235595; PMCID: PMC6628806.
https://www.ncbi.nlm.nih.gov/pubmed/31235595
Elfawal MA, Savinov SN, Aroian RV. Drug Screening for Discovery of Broad-spectrum Agents for Soil-transmitted Nematodes. Sci Rep. 2019;9(1):12347. Epub 2019/08/28. doi: 10.1038/s41598-019-48720-1. PubMed PMID: 31451730; PMCID: PMC6710243.
https://www.ncbi.nlm.nih.gov/pubmed/31451730
Farah S, Doloff JC, Muller P, Sadraei A, Han HJ, Olafson K, Vyas K, Tam HH, Hollister-Lock J, Kowalski PS, Griffin M, Meng A, McAvoy M, Graham AC, McGarrigle J, Oberholzer J, Weir GC, Greiner DL, Langer R, Anderson DG. Long-term implant fibrosis prevention in rodents and non-human primates using crystallized drug formulations. Nat Mater. 2019. Epub 2019/06/27. doi: 10.1038/s41563-019-0377-5. PubMed PMID: 31235902.
https://www.ncbi.nlm.nih.gov/pubmed/31235902
Feldman JL, Peterson CL. Yeast Sirtuin Family Members Maintain Transcription Homeostasis to Ensure Genome Stability. Cell Rep. 2019;27(10):2978-89 e5. Epub 2019/06/06. doi: 10.1016/j.celrep.2019.05.009. PubMed PMID: 31167142. https://www.ncbi.nlm.nih.gov/pubmed/31167142
Fernandez S, Viola JM, Torres A, Wallace M, Trefely S, Zhao S, Affronti HC, Gengatharan JM, Guertin DA, Snyder NW, Metallo CM, Wellen KE. Adipocyte ACLY Facilitates Dietary Carbohydrate Handling to Maintain Metabolic Homeostasis in Females. Cell Rep. 2019;27(9):2772-84 e6. Epub 2019/05/30. doi: 10.1016/j.celrep.2019.04.112. PubMed PMID: 31141698; PMCID: PMC6608748. https://www.ncbi.nlm.nih.gov/pubmed/31141698
Fischer DS, Fiedler AK, Kernfeld EM, Genga RMJ, Bastidas-Ponce A, Bakhti M, Lickert H, Hasenauer J, Maehr R, Theis FJ. Inferring population dynamics from single-cell RNA-sequencing time series data. Nat Biotechnol. 2019;37(4):461-8. Epub 2019/04/03. doi: 10.1038/s41587-019-0088-0. PubMed PMID: 30936567. https://www.ncbi.nlm.nih.gov/pubmed/30936567
Fitzgibbons TP, Lee N, Tran KV, Nicoloro S, Kelly M, Tam SK, Czech MP. Coronary disease is not associated with robust alterations in inflammatory gene expression in human epicardial fat. JCI Insight. 2019;4(20). Epub 2019/09/13. doi: 10.1172/jci.insight.124859. PubMed PMID: 31513547; PMCID: PMC6824304. https://www.ncbi.nlm.nih.gov/pubmed/31513547
Garcia B, Lee J, Edraki A, Hidalgo-Reyes Y, Erwood S, Mir A, Trost CN, Seroussi U, Stanley SY, Cohn RD, Claycomb JM, Sontheimer EJ, Maxwell KL, Davidson AR. Anti-CRISPR AcrIIA5 Potently Inhibits All Cas9 Homologs Used for Genome Editing. Cell Rep. 2019;29(7):1739-46 e5. Epub 2019/11/14. doi: 10.1016/j.celrep.2019.10.017. PubMed PMID: 31722192; PMCID: PMC6910239. https://www.ncbi.nlm.nih.gov/pubmed/31722192
Gawron MA, Duval M, Carbone C, Jaiswal S, Wallace A, Martin JC, 3rd, Dauphin A, Brehm MA, Greiner DL, Shultz LD, Luban J, Cavacini LA. Human Anti-HIV-1 gp120 Monoclonal Antibodies with Neutralizing Activity Cloned from Humanized Mice Infected with HIV-1. J Immunol. 2019;202(3):799-804. Epub 2018/12/30. doi: 10.4049/jimmunol.1801085. PubMed PMID: 30593536; PMCID: PMC6344273. https://www.ncbi.nlm.nih.gov/pubmed/30593536
Genga RMJ, Kernfeld EM, Parsi KM, Parsons TJ, Ziller MJ, Maehr R. Single-Cell RNA-Sequencing-Based CRISPRi Screening Resolves Molecular Drivers of Early Human Endoderm Development. Cell Rep. 2019;27(3):708-18 e10. Epub 2019/04/18. doi: 10.1016/j.celrep.2019.03.076. PubMed PMID: 30995470; PMCID: PMC6525305. https://www.ncbi.nlm.nih.gov/pubmed/30995470
Ghadieh HE, Russo L, Muturi HT, Ghanem SS, Manaserh IH, Noh HL, Suk S, Kim JK, Hill JW, Najjar SM. Hyperinsulinemia drives hepatic insulin resistance in male mice with liver-specific Ceacam1 deletion independently of lipolysis. Metabolism. 2019;93:33-43. Epub 2019/01/22. doi: 10.1016/j.metabol.2019.01.008. PubMed PMID: 30664851; PMCID: PMC6401268. https://www.ncbi.nlm.nih.gov/pubmed/30664851
Gramann AK, Venkatesan AM, Guerin M, Ceol CJ. Regulation of zebrafish melanocyte development by ligand-dependent BMP signaling. Elife. 2019;8. Epub 2019/12/24. doi: 10.7554/eLife.50047. PubMed PMID: 31868592.
https://www.ncbi.nlm.nih.gov/pubmed/31868592
Greer PL, Samuel MA. Becoming a Principal Investigator: Designing and Navigating Your Academic Adventure. Neuron. 2019;103(6):959-63. Epub 2019/09/27. doi: 10.1016/j.neuron.2019.08.023. PubMed PMID: 31557459.
https://www.ncbi.nlm.nih.gov/pubmed/31557459
Guilherme A, Henriques F, Bedard AH, Czech MP. Molecular pathways linking adipose innervation to insulin action in obesity and diabetes mellitus. Nat Rev Endocrinol. 2019;15(4):207-25. Epub 2019/02/09. doi: 10.1038/s41574-019-0165-y. PubMed PMID: 30733616.
https://www.ncbi.nlm.nih.gov/pubmed/30733616
Guo S, Pridham KJ, Virbasius CM, He B, Zhang L, Varmark H, Green MR, Sheng Z. A large-scale RNA interference screen identifies genes that regulate autophagy at different stages. Sci Rep. 2019;9(1):8382. Epub 2019/06/12. doi: 10.1038/s41598-019-42889-1. PubMed PMID: 31182720; PMCID: PMC6557834. https://www.ncbi.nlm.nih.gov/pubmed/31182720
Hamza Z, El-Hashash M, Aly S, Hathout A, Soto E, Sabry B, Ostroff G. Preparation and characterization of yeast cell wall beta-glucan encapsulated humic acid nanoparticles as an enhanced aflatoxin B1 binder. Carbohydr Polym. 2019;203:185-92. Epub 2018/10/16. doi: 10.1016/j.carbpol.2018.08.047. PubMed PMID: 30318202. https://www.ncbi.nlm.nih.gov/pubmed/30318202
Haraszti RA, Miller R, Dubuke ML, Rockwell HE, Coles AH, Sapp E, Didiot MC, Echeverria D, Stoppato M, Sere YY, Leszyk J, Alterman JF, Godinho B, Hassler MR, McDaniel J, Narain NR, Wollacott R, Wang Y, Shaffer SA, Kiebish MA, DiFiglia M, Aronin N, Khvorova A. Serum Deprivation of Mesenchymal Stem Cells Improves Exosome Activity and Alters Lipid and Protein Composition. iScience. 2019;16:230-41. Epub 2019/06/14. doi: 10.1016/j.isci.2019.05.029. PubMed PMID: 31195240; PMCID: PMC6562145.
https://www.ncbi.nlm.nih.gov/pubmed/31195240
Hayden CA, Hung CY, Zhang H, Negron A, Esquerra R, Ostroff G, Abraham A, Lopez AG, Gonzales JE, Howard JA. Maize-Produced Ag2 as a Subunit Vaccine for Valley Fever. J Infect Dis. 2019. Epub 2019/06/12. doi: 10.1093/infdis/jiz196. PubMed PMID: 31184702.
https://www.ncbi.nlm.nih.gov/pubmed/31184702
Heijink AM, Everts M, Honeywell ME, Richards R, Kok YP, de Vries EGE, Lee MJ, van Vugt M. Modeling of Cisplatin-Induced Signaling Dynamics in Triple-Negative Breast Cancer Cells Reveals Mediators of Sensitivity. Cell Rep. 2019;28(9):2345-57 e5. Epub 2019/08/29. doi: 10.1016/j.celrep.2019.07.070. PubMed PMID: 31461651; PMCID: PMC6718811.
https://www.ncbi.nlm.nih.gov/pubmed/31461651
Hester MM, Lee CK, Abraham A, Khoshkenar P, Ostroff GR, Levitz SM, Specht CA. Protection of mice against experimental cryptococcosis using glucan particle-based vaccines containing novel recombinant antigens. Vaccine. 2020;38(3):620-6. Epub 2019/11/09. doi: 10.1016/j.vaccine.2019.10.051. PubMed PMID: 31699504; PMCID: PMC6954324.
https://www.ncbi.nlm.nih.gov/pubmed/31699504
Hsiao WY, Guertin DA. De Novo Lipogenesis as a Source of Second Messengers in Adipocytes. Curr Diab Rep. 2019;19(11):138. Epub 2019/11/22. doi: 10.1007/s11892-019-1264-9. PubMed PMID: 31749022.
https://www.ncbi.nlm.nih.gov/pubmed/3174902
Hurtado Del Pozo C, Ruiz HH, Arivazhagan L, Aranda JF, Shim C, Daya P, Derk J, MacLean M, He M, Frye L, Friedline RH, Noh HL, Kim JK, Friedman RA, Ramasamy R, Schmidt AM. A Receptor of the Immunoglobulin Superfamily Regulates Adaptive Thermogenesis. Cell Rep. 2019;28(3):773-91 e7. Epub 2019/07/18. doi: 10.1016/j.celrep.2019.06.061. PubMed PMID: 31315054.
https://www.ncbi.nlm.nih.gov/pubmed/31315054
Ilbay O, Ambros V. Pheromones and Nutritional Signals Regulate the Developmental Reliance on let-7 Family MicroRNAs in C. elegans. Curr Biol. 2019;29(11):1735-45 e4. Epub 2019/05/21. doi: 10.1016/j.cub.2019.04.034. PubMed PMID: 31104929. https://www.ncbi.nlm.nih.gov/pubmed/31104929
Ilbay O, Ambros V. Regulation of nuclear-cytoplasmic partitioning by the lin-28-lin-46 pathway reinforces microRNA repression of HBL-1 to confer robust cell-fate progression in C. elegans. Development. 2019;146(21). Epub 2019/10/11. doi: 10.1242/dev.183111. PubMed PMID: 31597658; PMCID: PMC6857590.
https://www.ncbi.nlm.nih.gov/pubmed/31597658
Jangalwe S, Kapoor VN, Xu J, Girnius N, Kennedy NJ, Edwards YJK, Welsh RM, Davis RJ, Brehm MA. Cutting Edge: Early Attrition of Memory T Cells during Inflammation and Costimulation Blockade Is Regulated Concurrently by Proapoptotic Proteins Fas and Bim. J Immunol. 2019;202(3):647-51. Epub 2019/01/06. doi: 10.4049/jimmunol.1800278. PubMed PMID: 30610162; PMCID: PMC6344249. https://www.ncbi.nlm.nih.gov/pubmed/30610162
Jin YJ, Byun S, Han S, Chamberlin J, Kim D, Kim MJ, Lee Y. Differential alternative splicing regulation among hepatocellular carcinoma with different risk factors. BMC Med Genomics. 2019;12(Suppl 8):175. Epub 2019/12/21. doi: 10.1186/s12920-019-0635-z. PubMed PMID: 31856847; PMCID: PMC6923823.
https://www.ncbi.nlm.nih.gov/pubmed/31856847
Jung SM, Hung CM, Hildebrand SR, Sanchez-Gurmaches J, Martinez-Pastor B, Gengatharan JM, Wallace M, Mukhopadhyay D, Martinez Calejman C, Luciano AK, Hsiao WY, Tang Y, Li H, Daniels DL, Mostoslavsky R, Metallo CM, Guertin DA. Non-canonical mTORC2 Signaling Regulates Brown Adipocyte Lipid Catabolism through SIRT6-FoxO1. Mol Cell. 2019;75(4):807-22 e8. Epub 2019/08/24. doi: 10.1016/j.molcel.2019.07.023. PubMed PMID: 31442424.
https://www.ncbi.nlm.nih.gov/pubmed/31442424
Jung SM, Sanchez-Gurmaches J, Guertin DA. Brown Adipose Tissue Development and Metabolism. Handb Exp Pharmacol. 2019;251:3-36. Epub 2018/09/12. doi: 10.1007/164_2018_168. PubMed PMID: 30203328.
https://www.ncbi.nlm.nih.gov/pubmed/30203328
Kamga L, Gil A, Song I, Brody R, Ghersi D, Aslan N, Stern LJ, Selin LK, Luzuriaga K. CDR3alpha drives selection of the immunodominant Epstein Barr virus (EBV) BRLF1-specific CD8 T cell receptor repertoire in primary infection. PLoS Pathog. 2019;15(11):e1008122. Epub 2019/11/26. doi: 10.1371/journal.ppat.1008122. PubMed PMID: 31765434; PMCID: PMC6901265. https://www.ncbi.nlm.nih.gov/pubmed/31765434
Kant S, Craige SM, Chen K, Reif MM, Learnard H, Kelly M, Caliz AD, Tran KV, Ramo K, Peters OM, Freeman M, Davis RJ, Keaney JF, Jr. Neural JNK3 regulates blood flow recovery after hindlimb ischemia in mice via an Egr1/Creb1 axis. Nat Commun. 2019;10(1):4223. Epub 2019/09/19. doi: 10.1038/s41467-019-11982-4. PubMed PMID: 31530804; PMCID: PMC6748991.
https://www.ncbi.nlm.nih.gov/pubmed/31530804
Karlinsey JE, Stepien TA, Mayho M, Singletary LA, Bingham-Ramos LK, Brehm MA, Greiner DL, Shultz LD, Gallagher LA, Bawn M, Kingsley RA, Libby SJ, Fang FC. Genome-wide Analysis of Salmonella enterica serovar Typhi in Humanized Mice Reveals Key Virulence Features. Cell Host Microbe. 2019;26(3):426-34 e6. Epub 2019/08/27. doi: 10.1016/j.chom.2019.08.001. PubMed PMID: 31447308; PMCID: PMC6742556.
https://www.ncbi.nlm.nih.gov/pubmed/31447308
Kim DW, Chang C, Chen X, Doran AC, Gaudreault F, Wager T, DeMarco GJ, Kim JK. Systems approach reveals photosensitivity and PER2 level as determinants of clock-modulator efficacy. Mol Syst Biol. 2019;15(7):e8838. Epub 2019/07/30. doi: 10.15252/msb.20198838. PubMed PMID: 31353796; PMCID: PMC6613017. https://www.ncbi.nlm.nih.gov/pubmed/31353796
Kim K, Dauphin A, Komurlu S, McCauley SM, Yurkovetskiy L, Carbone C, Diehl WE, Strambio-De-Castillia C, Campbell EM, Luban J. Cyclophilin A protects HIV-1 from restriction by human TRIM5alpha. Nat Microbiol. 2019;4(12):2044-51. Epub 2019/10/23. doi: 10.1038/s41564-019-0592-5. PubMed PMID: 31636416; PMCID: PMC6879858.
https://www.ncbi.nlm.nih.gov/pubmed/31636416
Kucukural A, Yukselen O, Ozata DM, Moore MJ, Garber M. DEBrowser: interactive differential expression analysis and visualization tool for count data. BMC Genomics. 2019;20(1):6. Epub 2019/01/07. doi: 10.1186/s12864-018-5362-x. PubMed PMID: 30611200; PMCID: PMC6321710.
https://www.ncbi.nlm.nih.gov/pubmed/30611200
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