Selected Publications

Morrison Laboratory Publications since 2006:

Laliberte JP, McGinnes LW, Peeples ME, Morrison TG. Integrity of membrane lipid rafts is necessary for the ordered assembly and release of infectious Newcastle disease virus particles. J Virol. 2006 Nov;80(21):10652-62. PubMed PMID: 17041223; PubMed Central PMCID: PMC1641742.

Pantua HD, McGinnes LW, Peeples ME, Morrison TG. Requirements for the assembly and release of Newcastle disease virus-like particles. J Virol. 2006 Nov;80(22):11062-73. PubMed PMID: 16971425; PubMed Central PMCID: PMC1642154.

McGinnes, L, and Morrison, T. 2006 Inhibition of Receptor Binding Stabilizes Newcastle Disease Virus HN and F protein containing Complexes. J. Virol. 80: 2894-2903

Laliberte, J, P., McGinnes, L. W., Peeples, M. E., and Morrison, T. G. 2006 Integrity of Membrane Lipid Rafts is necessary for the Ordered Assembly and Release of Infectious Newcastle disease virus particles. J. Virol. 80: 10652-10662

Jain, S, McGinnes, L, and Morrison, T. 2007. Thiol/Disulfide Exchange is required for membrane fusion directed by the Newcastle disease virus Fusion protein. J. Virol. 81: 2328-2339.

Laliberte, J., McGinnes, L., and Morrison, T. 2007. Incorporation of functional HN-F glycoprotein-containing complexes into Newcastle disease virus is dependent on cholesterol and membrane lipid raft integrity. J. Virol. 81: 10636-10648.

Jain, S., McGinnes, L. W., and Morrison, T. G. 2008. Over expression of thiol/disulfide isomerases enhances membrane fusion directed by the Newcastle disease virus fusion protein. J. Virol. 82: 12039-12048.

Jain, S., McGinnes, L. W., and Morrison, T. G. 2009. Role of thiol/disulfide exchange in Newcastle disease virus entry. J. Virol. 83: 241-249. 10.1128/jvi.01407-08

Murawski, M. R., McGinnes, L.W., Finberg, R. W., Kurt-Jones, E. A., Massare, M.J., Smith, G, Heaton, P., Fraire, A. E., and Morrison, T. G., 2010. Newcastle disease virus-like particles containing respiratory syncytial virus (RSV) G protein induced protection in BALB/c mice with no evidence of immunopathology. J. Virol. 84: 1110-1123 10.1128/jvi.01709-09.

McGinnes LW, Pantua H, Laliberte JP, Gravel KA, Jain S, Morrison TG. Assembly and biological and immunological properties of Newcastle disease virus-like particles. J Virol. 2010 May;84(9):4513-23. PubMed PMID: 20181713; PubMed Central PMCID: PMC2863756.

McGinnes, L., Gravel, K., Finberg, R., Kurt-Jones, E., Massare, M., Smith, G., Schmidt, M., and Morrison, T. 2011. Assembly and immunological properties of Newcastle disease virus-like particles containing the respiratory syncytial virus F and G proteins. J. Virol. 85: 366-377.

Gravel KA, McGinnes LW, Reitter J, Morrison TG. The transmembrane domain sequence affects the structure and function of the Newcastle disease virus fusion protein. J Virol. 2011 Apr;85(7):3486-97. PubMed PMID: 21270151; PubMed Central PMCID: PMC3067846.

Schmidt, M. R., McGinnes, L. W., Kenward, S. A., Willems, K. N., Woodland, R. T., and Morrison, T. G. 2012. Long term and memory immune responses in mice against Newcastle disease virus-like particles containing respiratory syncytial virus glycoprotein ectodomains. J. Virol. 86: 11654-11662. doi:10.1128/JVI.01510-12. PMID22896618

Battisti A.J., Meng, G., Winkler, D. C., McGinnes, L. W., Plevka, P., Steven, A. J., Morrison, T. G., and Rossmann, M.G. 2012. Structure and assembly of a paramyxovirus matrix protein. PNAS USA 109: 13996-14000.

McGinnes, L. W., T. G. Morrison. 2013. Newcastle Disease Virus-Like Particles: Preparation, Purification, Quantification, and Incorporation of Foreign Glycoproteins. Current Protocols in Microbiology John Wiley & Sons, Inc. doi: 10.1002/9780471729259.mc1802s30

Schmidt, M. R., McGinnes, L. W., Kenward, S. A., Willems, K. N., Woodland, R. T., and Morrison, T. G. 2014. Modifications of the Respiratory Syncytial Virus F Protein in Virus-Like Particles Impacts Generation of B Cell Memory. J. Virol. 88: 10165-10176 PMID: 24965456 DOI: 10.1128/JVI.01250-1 10.1128/jvi.01250-14

Ogembo, J., Murawski, M., McGinnes, L., Parcharidou, A., Sutiwisesak, R., Tison, T., Avendano, J., Agnani, D., Finberg, R., Morrison, T., and Fingeroth, J., . 2015. A chimeric EBV gp350-220 based VLP replicates the virion-B cell attachment mechanism and elicits long-lasting, neutralizing antibody in mice. J. Translational Medicine 13: 50-64. PMID: 25885535 Doi: 10:1186/s12967-015-0415-02

McGinnes-Cullen, L., Blanco, J. C. G., Morrison, T. G. Cotton rat immune responses to virus-like particles containing the pre-fusion form of the respiratory syncytial virus fusion protein. 2015. J. of Trans. Med., 13: 350-363.

McGinnes-Cullen L, Schmidt MR, Kenward SA, Woodland RT, Morrison TG. Murine immune responses to virus-like particle-associated pre- and post-fusion forms of the respiratory syncytial virus F protein. J Virol. 2015 Jul;89(13):6835-47. PubMed PMID: 25903340; PubMed Central PMCID: PMC4468467. doi:10:1128/JVI.00384-15

Cullen, L., Schmidt, M. and Morrison, T. G. The Importance of RSV F Protein Conformation in VLPs In Stimulation of Neutralizing Antibody Titers in Mice Previously Infected with RSV 2017 Human Vaccines and Therapeutics June 12: 1-10 PMID28604155. doi: 1080/21645515.2017.

Blanco, J.C.G. Pletneva, L. M., McGinnes-Cullen, L., Otoa, R. O., Patel, M. C., Fernando, L. R., Bokhvalova, M. S., and Morrison, T. G. 2018. Efficacy of a respiratory syncytial virus vaccine candidate in a maternal immunization model. 2018. Nature Commun. May 15, doi: 101038/s41467-018-04216-6.

Lori M. Cullen, Madelyn R. Schmidt, Gretel M. Torres, Adam A. Capoferri, Trudy G. Morrison. Comparison of Immune Responses to Different Versions of VLP Associated Stabilized RSV Pre-Fusion F Protein. 2019. Vaccines 7:21 doi.org/10.3390/vaccines7010021.

Lori M. Cullen, Madelyn R. Schmidt, Trudy G. Morrison. Effect of Previous Respiratory Syncytial Virus Infection on Murine Immune Responses to F and G Protein Containing Virus-like Particles. 2019. J. Virology, 93 (9): e00087-19. doi: 10.1128/JVI.00087-19.

Blanco, J., Fernando, L., Zhang, W., Kamali, A., Boukhvalova, M., McGinnes-Cullen, L., and Morrison, T. Alternative Virus-Like Particle-Associated Pre-Fusion F proteins as Maternal Vaccines for Respiratory Syncytial Virus. 2019. J. Virology 93: e00914. 10.1128/JVI.00914-19

Cullen, L., Boukhvalova, M., Blanco, J., Morrison, T. Comparisons of Antibody Populations in Different Pre-Fusion F VLP Immunized Cotton Rat Dams and their Offspring. 2020. Vaccines 8: 133. doi 10.3390/vaccines8010133