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Core Services & Rates

The following are provided on a fee-for-service basis to researchers at UMass Chan Medical School, other academic institutions, and for-profit companies. Please contact us to discuss how we can help move your research forward and to get a quote.

Metabolomics

Relative quantitation of polar and non-polar metabolites using multiple chromatographies to cover different classes of metabolites.

Lipidomics

Relative quantification of lipids using an untargeted LCMS workflow that includes the use of Avanti EquiSplash internal lipid standard to give increased confidence of lipid annotation.

Fatty Acid Analysis (FAME, SCFA, Sterols)

Relative quantification of fatty acid methyl esters, short chain fatty acids, or sterols and related metabolites using GCMS.

Stable Isotope Tracing

High-resolution mass spectrometers are used to perform stable isotope tracing experiments to measure relative pathway contributions of specific metabolites and metabolic pathway activity. We will provide guidance on experimental design, choice of isotope tracer(s), and data analysis and interpretation.

Quantitative Metabolomics

Relative quantitation of a broad range of metabolites across the same biological matrix in different conditions is generally sufficient for most experiments. Occasionally knowing the absolute (molar) quantity of one or two metabolites in samples is required (e.g. when levels of a target metabolite need to be compared across different tissues or organisms). For this, we perform quantitative metabolomics, in which a matrix-matched (where possible) standard curve is prepared for the target metabolite and run alongside the experimental samples. Additional isotopically labeled internal standards are also required. To ensure accurate target metabolite quantitation we perform method development on both the target metabolite(s) and the biological matrix, and require our customers to provide standards.

FY25 Internal UMass Chan Investigator Pricing

We are a new facility and reserve the right to update our rates to accurately reflect our cost to perform services. Any rate changes will be communicated before services begin.

Current pricing is based on our customers extracting their own samples.

Pricing includes the cost of extraction reagents, our typical internal standard mix, and LCMS vials. 

Additional charges may apply when the use of other standards is required or when samples are run in multi-well plates. 

We plan to offer metabolite extraction as a service in the near future.

  • Polar Metabolomics (LCMS): $70/ sample

  • Non-polar Metabolomics (LCMS): $70/ sample

  • Lipidomics (LCMS): TBD

  • Fatty Acid Analysis or analysis by GCMS: $50/ sample

  • *Stable Isotope Tracing: $70/ sample

  • Quantitative Metabolomics (LCMS): $70/ sample PLUS cost of standard curve(s)

  • Quantitative Metabolomics (GCMS): $50/ sample PLUS cost of standard curve(s)

  • Standard Curve LCMS (Quantitative Metabolomics): $450/ curve

  • Standard Curve GCMS (Quantitative Metabolomics): $315/ curve

  • Data Processing and Analysis Fee: $150/ hour

All new projects are subject to a one-time $150 initial consultation fee

*Stable isotope tracing is NOT the same as metabolic flux analysis (MFA)

Contact us to discuss the most appropriate experiment for your research