Meet the Team
Caroline Lewis Chidley, PhD
Assistant Professor in Molecular Medicine and Metabolomics Core Director
Dr. Chidley earned her PhD in Biochemistry and Molecular Cell Biology from University College London, UK, and came to the U.S. for a postdoc in Matthew Vander Heiden’s laboratory at MIT in Cambridge, MA, where her research focused on cancer metabolism. She has been applying LCMS to biological questions for 12 years, with a focus on high-resolution mass spectrometry, stable isotope tracing experiments, and untargeted metabolomics.
She joined the Program in Molecular Medicine at UMass Chan Medical School in 2022 from the Whitehead Institute for Biomedical Research, where she directed the Metabolite Profiling Core Facility for five years. Outside the lab, Caroline enjoys spending time with friends and family, walking her dog, and singing in a choir.
John Haley, PhD
Research Associate IV, Metabolomics
Dr. Haley completed his doctoral training at UMass Chan Medical School during which he used LCMS & GCMS-based technologies to study the metabolism of brown adipose tissue and the liver in the context of thermogenesis, obesity, and liver disease. He miniaturized a metabolomics method in mice to sample arterial and venous blood to calculate metabolite flux across specific tissues, which was previously reserved for larger animals such as pigs and rats. Dr. Haley has worked with many types of biological materials including mouse and human tissue/serum, adherent and suspension cells.
He remains interested in the intersection of metabolism and signaling with specific interests in metabolic disease and glutamine metabolism. Outside of lab, John enjoys a wide range of activities like sailing, skiing, hiking, cooking, and reading.
Jaedon Sadler, BSc
Research Associate I, Metabolomics
Jaedon graduated from Penn State University with a degree in Biochemistry and Molecular Biology. As an undergraduate researcher, he worked under Dr. Melanie McReynolds, focusing on the Acute Kidney Injury-mediated dysfunction of NAD+ synthesis mechanisms. In his free time, Jaedon enjoys cooking, playing basketball, and spending time with his friends and family.