Instrumentation and Equipment
The lab currently comprises three high-resolution accurate-mass spectrometers, all coupled to custom-configured HPLC systems, and one GCMS system:
Thermo Exploris 240 Hybrid Mass Spectrometer
Coupled to Thermo Vanquish HPLC. Applications include targeted & untargeted polar metabolomics.
Thermo IQX Tribrid Mass Spectrometer #1
Coupled to Thermo Vanquish HPLC. Applications include stable isotope tracing, polar untargeted metabolomics & MSn experiments.
Thermo IQX Tribrid Mass Spectrometer #2
Coupled to Thermo Vanquish HPLC. Applications include untargeted lipidomics & MSn experiments.
Agilent 8890 GCMS
Applications include fatty acid analysis FAME & SCFA, and analysis of steroids and other volatile compounds.
Specialist Equipment
Our users have access to the following that are available in our laboratory:
Bead Beater
Ideal for homogenization of worms, flies, and stool. Compatible with multiple tube types and sizes.
Cryo Mill
For pulverization of larger amounts of frozen tissue.
Refrigerated Speed-Vac
Compatible with 1.5 ml, 2 mL tubes and plates.
Nitrogen dryer
Compatible with 1.5 mL tubes, 2 mL LCMS vials and plates.
Agilent Bravo Metabolomics Sample Prep Platform*
Ideal for large numbers of plasma samples. *Additional cost.
Processing Computers with Vendor-specific software
Provided for user data processing and analysis.