Postdoc Position Available (updated 9/2021)

Modeling vascular malformations using the zebrafish
A postdoctoral position is available in the Lawson Lab at the UMass Chan Medical School to establish zebrafish models for vascular malformations. This project is focused on modeling the R183Q mutation in the G-protein, GNAQ, which is causative for Sturge-Weber syndrome (SWS). This NIH-funded work is a collaborative effort with Drs. Joyce Bischoff and Arin Greene at Boston Children's Hospital. This position provides the opportunity to work in a multidisciplinary team focused on identifying developmental mechanisms of SWS progression and logical therapeutic targets. Our efforts in the Lawson Lab focus on establishing zebrafish bearing GNAQ R183Q, along with detailed cellular and molecular characterization of the resulting phenotypes. Follow-up studies will include application of small molecule screening to identify therapeutic leads using the zebrafish model.  

The ideal candidate must have experience in molecular biology as documented through their publication record. Prior expertise in the application of genome editing and/or transgenesis is welcome and experience with model organisms is preferred.  Applicants must otherwise be highly motivated and technically accomplished as documented by exceptional publication record.

Please email CV and reprints of relevant publications to the contact information below.  Applicants accepted for initial consideration will be subsequently contacted for letters of reference.

Nathan D. Lawson, PhD
Professor
Department of Molecular, Cell, and Cancer Biology
UMass Chan Medical School
Lazare Research Building, Room 617
364 Plantation Street
Worcester, MA 01605
e-mail: nathan.lawson@umassmed.edu