Lab News

Our latest bioRxiv preprints

Dcp2 C-terminal Cis-Binding Elements Control Selective Targeting of the Decapping Enzyme by Forming Distinct Decapping Complexes
Feng He, Chan Wu, Allan Jacobson
https://www.biorxiv.org/content/10.1101/2021.10.01.462794v1

Ganesan, R., Mangkalaphiban, K., Baker, R.E., He, F., and Jacobson, A. Progressive polysomal association of Upf1, Upf2, and Upf3 as ribosomes traverse mRNA coding regions. bioRxiv: https://doi.org/10.1101/2021.12.03.471156, 2021.

Our latest papers

He, F., Wu, C., and Jacobson, A. Dcp2 C-terminal cis-binding elements control selective targeting of the decapping enzyme by forming distinct decapping complexes. eLife 11:e74410, 2022.

He, F. and Jacobson, A. Eukaryotic mRNA decapping factors: molecular mechanisms and activity. FEBS J. https://doi:10.1111/febs.16626, 2022.

Ganesan, R., Mangkalaphiban, K., Baker, R.E., He, F., and Jacobson, A. Ribosome-bound Upf1 forms distinct 80S complexes and conducts mRNA surveillance. RNA 28: 1621-1642, 2022.