, Graduate School of Biomedical Sciences, School of Medicine, Faculty, Research, Wen Xue, RNA Therapeutics Institute, Program in Molecular Medicine, Elinor Karlsson, Latest News, Xue Lab, Top Stories,
Nov 18, 2021
Flotte lab to develop gene therapy models for genetic lung disease
Researchers from UMass Chan Medical School have received a five-year $13.6 million program project grant from the National Heart, Lung and Blood Institute to develop new gene therapy models for alpha-1 antitrypsin deficiency, a chronic, debilitating genetic lung disease that shortens the lifespan.
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, Graduate School of Biomedical Sciences, School of Medicine, Faculty, Rare Disease, Terence Flotte, gene therapy, Guangping Gao, Wen Xue, Flotte Lab, Wang Lab, Dan Wang, Pediatrics, RNA Therapeutics Institute, Li Weibo Institute for Rare Diseases Research, Gruntman Lab, Microbiology and Physiological Systems,
Apr 7, 2021
Erik Sontheimer co-leading efforts to develop gene editing toolkit by NIH Somatic Cell Genome Editing Consortium
Six UMass Medical School scientists are among the members of the National Institutes of Health’s Somatic Cell Genome Editing Consortium to publish a paper in Nature outlining the program’s goals.
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, Graduate School of Biomedical Sciences, School of Medicine, Cancer Center, Watts Lab, Faculty, Rare Disease, Guangping Gao, Anastasia Khvorova, Jonathan K. Watts, Scot A. Wolfe, Wen Xue, Wolfe Lab, Sontheimer Lab, Molecular, Cell and Cancer Biology, RNA Therapeutics Institute, Li Weibo Institute for Rare Diseases Research, Gao Lab, Microbiology and Physiological Systems,
Jun 4, 2020
MD/PhD-student-led research finds potential new gene target for pediatric liver cancer
A new study by a team of UMass Medical School researchers, led by Jordan Smith, MD/PhD candidate, has identified a new therapeutic target in hepatoblastoma, a rare, primarily pediatric liver cancer.
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, School of Medicine, Cancer Center, Faculty, Student, MD/PhD, Wen Xue, Liver Cancer, Biochemistry and Molecular Biotechnology, RNA Therapeutics Institute, Pediatric Hematology/Oncology,
Sep 23, 2016
Wen Xue receives $250,000 for pediatric cancer research from Hyundai Hope on Wheels
UMass Medical School cancer researcher Wen Xue, PhD, accepted a $250,000 grant Friday from the Hyundai Motor America Hope on Wheels campaign to continue his work toward improving care and treatment options for children with cancer.
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, Cancer Center, Wen Xue, Liver Cancer,
Feb 1, 2016
CRISPR/Cas9 therapeutic for Tyrosinemia type I delivered to mice
According to a study published in Nature Biotechnology, a more efficient delivery of a CRISPR/Cas9 therapeutic to adult mice with the metabolic disease Tyrosinemia type I developed by Wen Xue, PhD, may also prove to be safer for use in humans.