Publications 2023
Adams, G., Moreno, G.K., Petros, B.A., Uddin, R., Levine, Z., Kotzen, B., Messer, K., Dobbins, S.T., DeRuff, K.C., Loreth, C., et al. (2023). The 2022 RSV surge was driven by multiple viral lineages. medRxiv. doi:10.1101/2023.01.04.23284195. PMCID: PMC9844019
https://www.ncbi.nlm.nih.gov/pubmed/36656774
Adler, B.A., Trinidad, M.I., Bellieny-Rabelo, D., Zhang, E., Karp, H.M., Skopintsev, P., Thornton, B.W., Weissman, R.F., Yoon, P.H., Chen, L., et al. (2023). CasPEDIA Database: a functional classification system for class 2 CRISPR-Cas enzymes. Nucleic Acids Res. Online ahead of print doi:10.1093/nar/gkad890.
https://www.ncbi.nlm.nih.gov/pubmed/37889041
Alexander, K.D., Ramachandran, S., Biswas, K., Lambert, C.M., Russell, J., Oliver, D.B., Armstrong, W., Rettler, M., Liu, S., Doitsidou, M., et al. (2023). The homeodomain transcriptional regulator DVE-1 directs a program for synapse elimination during circuit remodeling. Nat Commun 14, 7520. doi:10.1038/s41467-023-43281-4. PMCID: PMC10657367
https://www.ncbi.nlm.nih.gov/pubmed/37980357
Andolina, C., Ramjith, J., Rek, J., Lanke, K., Okoth, J., Grignard, L., Arinaitwe, E., Briggs, J., Bailey, J., Aydemir, O., et al. (2023). Plasmodium falciparum gametocyte carriage in longitudinally monitored incident infections is associated with duration of infection and human host factors. Sci Rep 13, 7072. doi:10.1038/s41598-023-33657-3. PMCID: PMC10150352
https://www.ncbi.nlm.nih.gov/pubmed/37127688
Andrews, G., Fan, K., Pratt, H.E., Phalke, N., Zoonomia Consortium section, s., Karlsson, E.K., Lindblad-Toh, K., Gazal, S., Moore, J.E., and Weng, Z. (2023). Mammalian evolution of human cis-regulatory elements and transcription factor binding sites. Science 380, eabn7930. doi:10.1126/science.abn7930.
https://www.ncbi.nlm.nih.gov/pubmed/37104580
Aroian, R.V., Loukas, A., and Martin, R.J. (2023). Anthelmintics V: Drugs, resistance, and vaccines. Int J Parasitol 53, 391-392. doi:10.1016/j.ijpara.2023.05.004. PMCID: PMC10226775
https://www.ncbi.nlm.nih.gov/pubmed/37257805
Aryee, K.E., Shultz, L.D., Burzenski, L.M., Greiner, D.L., and Brehm, M.A. (2023). NOD-scid IL2rgammanull mice lacking TLR4 support human immune system development and the study of human-specific innate immunity. J Leukoc Biol 113, 418-433. doi:10.1093/jleuko/qiac020.
https://www.ncbi.nlm.nih.gov/pubmed/36801998
Baier, A.S., Gioacchini, N., Eek, P., Tan, S., and Peterson, C.L. (2023). Dual engagement of the nucleosomal acidic patches is essential for deposition of histone H2A.Z by SWR1C. Res Sq. doi:10.21203/rs.3.rs-3050911/v1. PMCID: PMC10402270
https://www.ncbi.nlm.nih.gov/pubmed/37546845
Bakey, Z., Cabrera, O.A., Hoefele, J., Antony, D., Wu, K., Stuck, M.W., Micha, D., Eguether, T., Smith, A.O., van der Wel, N.N., et al. (2023). IFT74 variants cause skeletal ciliopathy and motile cilia defects in mice and humans. PLoS Genet 19, e1010796. doi:10.1371/journal.pgen.1010796. PMCID: PMC10298753
https://www.ncbi.nlm.nih.gov/pubmed/37315079
Bamidele, N., Zhang, H., Dong, X., Gaston, N., Cheng, H., Kelly, K., Watts, J.K., Xie, J., Gao, G., and Sontheimer, E.J. (2023). Engineering Nme2Cas9 Adenine Base Editors with Improved Activity and Targeting Scope. bioRxiv. doi:10.1101/2023.04.14.536905. PMCID: PMC10153126
https://www.ncbi.nlm.nih.gov/pubmed/37131611
Bryll, A.R., and Peterson, C.L. (2023). The circular logic of mRNA homeostasis. Transcription 14, 18-26. doi:10.1080/21541264.2023.2183684. PMCID: PMC10353332
https://www.ncbi.nlm.nih.gov/pubmed/36843061
Cao, J., Yu, T., Xu, B., Hu, Z., Zhang, X.O., Theurkauf, W.E., and Weng, Z. (2023). Epigenetic and chromosomal features drive transposon insertion in Drosophila melanogaster. Nucleic Acids Res 51, 2066-2086. doi:10.1093/nar/gkad054. PMCID: PMC10018349
https://www.ncbi.nlm.nih.gov/pubmed/36762470
Ceol, C.J. (2023). Microenvironmental GABA Signaling Regulates Melanomagenesis through Reciprocal Melanoma-Keratinocyte Communication. Cancer Discov 13, 2128-2130. doi:10.1158/2159-8290.CD-23-0843.
https://www.ncbi.nlm.nih.gov/pubmed/37794841
Chen, Y., Lei, X., Jiang, Z., Humphries, F., Parsi, K.M., Mustone, N.J., Ramos, I., Mutetwa, T., Fernandez-Sesma, A., Maehr, R., et al. (2023). Cellular nucleic acid-binding protein restricts SARS-CoV-2 by regulating interferon and disrupting RNA-protein condensates. Proc Natl Acad Sci U S A 120, e2308355120. doi:10.1073/pnas.2308355120. PMCID: PMC10666094
https://www.ncbi.nlm.nih.gov/pubmed/37963251
Chen, Z., Kwan, S.Y., Mir, A., Hazeltine, M., Shin, M., Liang, S.Q., Chan, I.L., Kelly, K., Ghanta, K.S., Gaston, N., et al. (2023). A Fluorescent Reporter Mouse for In Vivo Assessment of Genome Editing with Diverse Cas Nucleases and Prime Editors. CRISPR J 6, 570-582. doi:10.1089/crispr.2023.0048. PMCID: PMC10753986
https://www.ncbi.nlm.nih.gov/pubmed/38108517
Chibaya, L., Lusi, C.F., DeMarco, K.D., Kane, G.I., Brassil, M.L., Parikh, C.N., Murphy, K.C., Li, J., Naylor, T.E., Cerrutti, J., et al. (2023). Nanoparticle delivery of innate immune agonists combines with senescence-inducing agents to mediate T cell control of pancreatic cancer. bioRxiv. doi:10.1101/2023.09.18.558307. PMCID: PMC10542133
https://www.ncbi.nlm.nih.gov/pubmed/37790484
Chibaya, L., Murphy, K.C., DeMarco, K.D., Gopalan, S., Liu, H., Parikh, C.N., Lopez-Diaz, Y., Faulkner, M., Li, J., Morris, J.P.t., et al. (2023). EZH2 inhibition remodels the inflammatory senescence-associated secretory phenotype to potentiate pancreatic cancer immune surveillance. Nat Cancer 4, 872-892. doi:10.1038/s43018-023-00553-8. PMCID: PMC10516132
https://www.ncbi.nlm.nih.gov/pubmed/37142692
Chio, U.S., Rechiche, O., Bryll, A.R., Zhu, J., Feldman, J.L., Peterson, C.L., Tan, S., and Armache, J.P. (2023). Cryo-EM structure of the human Sirtuin 6-nucleosome complex. bioRxiv. doi:10.1101/2023.03.17.533206. PMCID: PMC10055229
https://www.ncbi.nlm.nih.gov/pubmed/36993468
Chio, U.S., Rechiche, O., Bryll, A.R., Zhu, J., Leith, E.M., Feldman, J.L., Peterson, C.L., Tan, S., and Armache, J.P. (2023). Cryo-EM structure of the human Sirtuin 6-nucleosome complex. Sci Adv 9, eadf7586. doi:10.1126/sciadv.adf7586. PMCID: PMC10104460
https://www.ncbi.nlm.nih.gov/pubmed/37058572
Christmas, M.J., Kaplow, I.M., Genereux, D.P., Dong, M.X., Hughes, G.M., Li, X., Sullivan, P.F., Hindle, A.G., Andrews, G., Armstrong, J.C., et al. (2023). Evolutionary constraint and innovation across hundreds of placental mammals. Science 380, eabn3943. doi:10.1126/science.abn3943. PMCID: PMC10250106
https://www.ncbi.nlm.nih.gov/pubmed/37104599
Chuprin, J., Buettner, H., Seedhom, M.O., Greiner, D.L., Keck, J.G., Ishikawa, F., Shultz, L.D., and Brehm, M.A. (2023). Humanized mouse models for immuno-oncology research. Nat Rev Clin Oncol 20, 192-206. doi:10.1038/s41571-022-00721-2. PMCID: PMC10593256
https://www.ncbi.nlm.nih.gov/pubmed/36635480
Connelly, S.V., Brazeau, N.F., Msellem, M., Ngasala, B.E., Aydemir, O., Goel, V., Niare, K., Giesbrecht, D.J., Popkin-Hall, Z.R., Hennelly, C.M., et al. (2023). Strong isolation by distance and evidence of population microstructure reflect ongoing Plasmodium falciparum transmission in Zanzibar. medRxiv. doi:10.1101/2023.02.15.23285960. PMCID: PMC9980253
https://www.ncbi.nlm.nih.gov/pubmed/36865135
Dagdeviren, S., Hoang, M.F., Sarikhani, M., Meier, V., Benoit, J.C., Okawa, M.C., Melnik, V.Y., Ricci-Blair, E.M., Foot, N., Friedline, R.H., et al. (2023). An insulin-regulated arrestin domain protein controls hepatic glucagon action. J Biol Chem 299, 105045. doi:10.1016/j.jbc.2023.105045. PMCID: PMC10413355
https://www.ncbi.nlm.nih.gov/pubmed/37451484
Derr, A.G., Arowosegbe, A., Satish, B., Redick, S.D., Qaisar, N., Guo, Z., Vanderleeden, E., Trombly, M.I., Baer, C.E., Harlan, D.M., et al. (2023). An Early Islet Transcriptional Signature Is Associated With Local Inflammation in Autoimmune Diabetes. Diabetes 72, 261-274. doi:10.2337/db22-0521. PMCID: PMC9871196
https://www.ncbi.nlm.nih.gov/pubmed/36346618
Devarajan, P., Vong, A.M., Castonguay, C.H., Silverstein, N.J., Kugler-Umana, O., Bautista, B.L., Kelly, K.A., Luban, J., and Swain, S.L. (2023). Cytotoxic CD4 development requires CD4 effectors to concurrently recognize local antigen and encounter type I IFN-induced IL-15. Cell Rep 42, 113182. doi:10.1016/j.celrep.2023.113182.
https://www.ncbi.nlm.nih.gov/pubmed/37776519
Doloff, J.C., Ma, M., Sadraei, A., Tam, H.H., Farah, S., Hollister-Lock, J., Vegas, A.J., Veiseh, O., Quiroz, V.M., Rakoski, A., et al. (2023). Identification of a humanized mouse model for functional testing of immune-mediated biomaterial foreign body response. Sci Adv 9, eade9488. doi:10.1126/sciadv.ade9488. PMCID: PMC10275594
https://www.ncbi.nlm.nih.gov/pubmed/37327334
Doxsey, D.D., Tettoni, S.D., Egri, S.B., and Shen, K. (2023). Redundant electrostatic interactions between GATOR1 and the Rag GTPase heterodimer drive efficient amino acid sensing in human cells. J Biol Chem 299, 104880. doi:10.1016/j.jbc.2023.104880. PMCID: PMC10316081
https://www.ncbi.nlm.nih.gov/pubmed/37269949
Egri, S.B., Wang, X., Diaz-Salinas, M.A., Luban, J., Dudkina, N.V., Munro, J.B., and Shen, K. (2023). Detergent modulates the conformational equilibrium of SARS-CoV-2 Spike during cryo-EM structural determination. Nat Commun 14, 2527. doi:10.1038/s41467-023-38251-9. PMCID: PMC10154187
https://www.ncbi.nlm.nih.gov/pubmed/37137903
Fanelli, M.J., Welsh, C.M., Lui, D.S., Smulan, L.J., and Walker, A.K. (2023). Immunity-linked genes are stimulated by a membrane stress pathway linked to Golgi function and the ARF-1 GTPase. Sci Adv 9, eadi5545. doi:10.1126/sciadv.adi5545. PMCID: PMC10699786
https://www.ncbi.nlm.nih.gov/pubmed/38055815
Ferreira, V., Folgueira, C., Garcia-Altares, M., Guillen, M., Ruiz-Rosario, M., DiNunzio, G., Garcia-Martinez, I., Alen, R., Bookmeyer, C., Jones, J.G., et al. (2023). Hypothalamic JNK1-hepatic fatty acid synthase axis mediates a metabolic rewiring that prevents hepatic steatosis in male mice treated with olanzapine via intraperitoneal: Additional effects of PTP1B inhibition. Redox Biol 63, 102741. doi:10.1016/j.redox.2023.102741. PMCID: PMC10225935
https://www.ncbi.nlm.nih.gov/pubmed/37230004
Foley, N.M., Mason, V.C., Harris, A.J., Bredemeyer, K.R., Damas, J., Lewin, H.A., Eizirik, E., Gatesy, J., Karlsson, E.K., Lindblad-Toh, K., et al. (2023). A genomic timescale for placental mammal evolution. Science 380, eabl8189. doi:10.1126/science.abl8189. PMCID: PMC10233747
https://www.ncbi.nlm.nih.gov/pubmed/37104581
Francis, R.J.B., San Agustin, J.T., Szabo Rogers, H.L., Cui, C., Jonassen, J.A., Eguether, T., Follit, J.A., Lo, C.W., and Pazour, G.J. (2023). Autonomous and non-cell autonomous role of cilia in structural birth defects in mice. PLoS Biol 21, e3002425. doi:10.1371/journal.pbio.3002425. PMCID: PMC10735189
https://www.ncbi.nlm.nih.gov/pubmed/38079449
Frantz, W.T., Iyengar, S., Neiswender, J., Cousineau, A., Maehr, R., and Ceol, C.J. (2023). Pigment cell progenitor heterogeneity and reiteration of developmental signaling underlie melanocyte regeneration in zebrafish. Elife 12. doi:10.7554/eLife.78942. PMCID: PMC10139689
https://www.ncbi.nlm.nih.gov/pubmed/37021774
Godbole, A.A., Gopalan, S., Nguyen, T.K., Munden, A.L., Lui, D.S., Fanelli, M.J., Vo, P., Lewis, C.A., Spinelli, J.B., Fazzio, T.G., and Walker, A.K. (2023). S-adenosylmethionine synthases specify distinct H3K4me3 populations and gene expression patterns during heat stress. Elife 12. doi:10.7554/eLife.79511. PMCID: PMC9984191
https://www.ncbi.nlm.nih.gov/pubmed/36756948
Gong, J., Nirala, N.K., Chen, J., Wang, F., Gu, P., Wen, Q., Ip, Y.T., and Xiang, Y. (2023). TrpA1 is a shear stress mechanosensing channel regulating intestinal stem cell proliferation in Drosophila. Sci Adv 9, eadc9660. doi:10.1126/sciadv.adc9660. PMCID: PMC10208578
https://www.ncbi.nlm.nih.gov/pubmed/37224252
Goo, B.S., Mun, D.J., Kim, S., Nhung, T.T.M., Lee, S.B., Woo, Y., Kim, S.J., Suh, B.K., Park, S.J., Lee, H.E., et al. (2023). Schizophrenia-associated Mitotic Arrest Deficient-1 (MAD1) regulates the polarity of migrating neurons in the developing neocortex. Mol Psychiatry 28, 856-870. doi:10.1038/s41380-022-01856-5. PMCID: PMC9908555
https://www.ncbi.nlm.nih.gov/pubmed/36357673
Guertin, D.A., and Wellen, K.E. (2023). Acetyl-CoA metabolism in cancer. Nat Rev Cancer 23, 156-172. doi:10.1038/s41568-022-00543-5.
https://www.ncbi.nlm.nih.gov/pubmed/36658431
Guilherme, A., Rowland, L.A., Wang, H., and Czech, M.P. (2023). The adipocyte supersystem of insulin and cAMP signaling. Trends Cell Biol 33, 340-354. doi:10.1016/j.tcb.2022.07.009. PMCID: PMC10339226
https://www.ncbi.nlm.nih.gov/pubmed/35989245
Guilherme, A., Rowland, L.A., Wetoska, N., Tsagkaraki, E., Santos, K.B., Bedard, A.H., Henriques, F., Kelly, M., Munroe, S., Pedersen, D.J., et al. (2023). Acetyl-CoA carboxylase 1 is a suppressor of the adipocyte thermogenic program. Cell Rep 42, 112488. doi:10.1016/j.celrep.2023.112488. PMCID: PMC10286105
https://www.ncbi.nlm.nih.gov/pubmed/37163372
Guney, M.H., Nagalekshmi, K., McCauley, S.M., Carbone, C., Aydemir, O., and Luban, J. (2023). IFIH1 (MDA5) is required for innate immune detection of intron-containing RNA expressed from the HIV-1 provirus. bioRxiv. doi:10.1101/2023.11.17.567619. PMCID: PMC10680824
https://www.ncbi.nlm.nih.gov/pubmed/38014177
Gupta, M., and Pazour, G.J. (2023). Intraflagellar transport: A critical player in photoreceptor development and the pathogenesis of retinal degenerative diseases. Cytoskeleton (Hoboken). doi:10.1002/cm.21823.
https://www.ncbi.nlm.nih.gov/pubmed/38140908
Haley, J.A., Jang, C., and Guertin, D.A. (2023). A new era of understanding in vivo metabolic flux in thermogenic adipocytes. Curr Opin Genet Dev 83, 102112. doi:10.1016/j.gde.2023.102112.
https://www.ncbi.nlm.nih.gov/pubmed/37703635
Hariharan, V.N., Shin, M., Chang, C.W., O'Reilly, D., Biscans, A., Yamada, K., Guo, Z., Somasundaran, M., Tang, Q., Monopoli, K., et al. (2023). Divalent siRNAs are bioavailable in the lung and efficiently block SARS-CoV-2 infection. Proc Natl Acad Sci U S A 120, e2219523120. doi:10.1073/pnas.2219523120. PMCID: PMC10089225
https://www.ncbi.nlm.nih.gov/pubmed/36893269
Harmon, C., Zaborowski, A., Moore, H., St Louis, P., Slattery, K., Duquette, D., Scanlan, J., Kane, H., Kunkemoeller, B., McIntyre, C.L., et al. (2023). gammadelta T cell dichotomy with opposing cytotoxic and wound healing functions in human solid tumors. Nat Cancer 4, 1122-1137. doi:10.1038/s43018-023-00589-w.
https://www.ncbi.nlm.nih.gov/pubmed/37474835
Herbert, C., Manabe, Y.C., Filippaios, A., Lin, H., Wang, B., Achenbach, C., Kheterpal, V., Hartin, P., Suvarna, T., Harman, E., et al. (2023). Differential Viral Dynamics by Sex and Body Mass Index During Acute SARS-CoV-2 Infection: Results from a Longitudinal Cohort Study. Clin Infect Dis. doi:10.1093/cid/ciad701.
https://www.ncbi.nlm.nih.gov/pubmed/37972270
Ho, S., Rice, N.P., Yu, T., Weng, Z., and Theurkauf, W.E. (2023). Aub, Vasa and Armi localization to phase separated nuage is dispensable for piRNA biogenesis and transposon silencing in Drosophila. bioRxiv. doi:10.1101/2023.07.25.549160. PMCID: PMC10402007
https://www.ncbi.nlm.nih.gov/pubmed/37546958
Honeywell, M.E., Isidor, M.S., Harper, N.W., Fontana, R.E., Cruz-Gordillo, P., Porto, S.A., Fraser, C.S., Sarosiek, K.A., Guertin, D.A., Spinelli, J.B., and Lee, M.J. (2023). p53 controls choice between apoptotic and non-apoptotic death following DNA damage. bioRxiv. doi:10.1101/2023.01.17.524444. PMCID: PMC9882237
https://www.ncbi.nlm.nih.gov/pubmed/36712034
Huang, L., Liu, P., Du, Y., Pan, D., Lee, A., Wolfe, S.A., and Wang, Y.X. (2023). A brown fat-enriched adipokine, ASRA, is a leptin receptor antagonist that stimulates appetite. bioRxiv. doi:10.1101/2023.09.12.557454. PMCID: PMC10515849
https://www.ncbi.nlm.nih.gov/pubmed/37745491
Huang, Y.S., Mendez, R., Fernandez, M., and Richter, J.D. (2023). CPEB and translational control by cytoplasmic polyadenylation: impact on synaptic plasticity, learning, and memory. Mol Psychiatry 28, 2728-2736. doi:10.1038/s41380-023-02088-x. PMCID: PMC10620108
https://www.ncbi.nlm.nih.gov/pubmed/37131078
Itah, Z., Chaudhry, S., Raju Ponny, S., Aydemir, O., Lee, A., Cavanagh-Kyros, J., Tournier, C., Muller, W.J., and Davis, R.J. (2023). HER2-driven breast cancer suppression by the JNK signaling pathway. Proc Natl Acad Sci U S A 120, e2218373120. doi:10.1073/pnas.2218373120. PMCID: PMC9942916
https://www.ncbi.nlm.nih.gov/pubmed/36656864
Jain, A., Govindan, R., Berkman, A.R., Luban, J., Diaz-Salinas, M.A., Durham, N.D., and Munro, J.B. (2023). Regulation of Ebola GP conformation and membrane binding by the chemical environment of the late endosome. PLoS Pathog 19, e1011848. doi:10.1371/journal.ppat.1011848. PMCID: PMC10727438
https://www.ncbi.nlm.nih.gov/pubmed/38055723
Jiang, H.C., Park, S.J., Wang, I.H., Bear, D.M., Nowlan, A., and Greer, P.L. (2023). CD20 is a mammalian odorant receptor expressed in a subset of olfactory sensory neurons that mediates innate avoidance of predators. Res Sq. doi:10.21203/rs.3.rs-3290152/v1. PMCID: PMC10543371
https://www.ncbi.nlm.nih.gov/pubmed/37790559
Jung, S., Shah, S., Han, G., and Richter, J.D. (2023). FMRP deficiency leads to multifactorial dysregulation of splicing and mislocalization of MBNL1 to the cytoplasm. PLoS Biol 21, e3002417. doi:10.1371/journal.pbio.3002417. PMCID: PMC10721184
https://www.ncbi.nlm.nih.gov/pubmed/38048343
Kearns, N.A., Lobo, M., Genga, R.M.J., Abramowitz, R.G., Parsi, K.M., Min, J., Kernfeld, E.M., Huey, J.D., Kady, J., Hennessy, E., et al. (2023). Generation and molecular characterization of human pluripotent stem cell-derived pharyngeal foregut endoderm. Dev Cell 58, 1801-1818 e1815. doi:10.1016/j.devcel.2023.08.024. PMCID: PMC10637111
https://www.ncbi.nlm.nih.gov/pubmed/37751684
Keough, K.C., Whalen, S., Inoue, F., Przytycki, P.F., Fair, T., Deng, C., Steyert, M., Ryu, H., Lindblad-Toh, K., Karlsson, E., et al. (2023). Three-dimensional genome rewiring in loci with human accelerated regions. Science 380, eabm1696. doi:10.1126/science.abm1696.
https://www.ncbi.nlm.nih.gov/pubmed/37104607
Ketchesin, K.D., Becker-Krail, D.D., Xue, X., Wilson, R.S., Lam, T.T., Williams, K.R., Nairn, A.C., Tseng, G.C., and Logan, R.W. (2023). Differential Effects of Cocaine and Morphine on the Diurnal Regulation of the Mouse Nucleus Accumbens Proteome. J Proteome Res 22, 2377-2390. doi:10.1021/acs.jproteome.3c00126. PMCID: PMC10392613
https://www.ncbi.nlm.nih.gov/pubmed/37311105
Kraus, C., and Sontheimer, E.J. (2023). Applications of Anti-CRISPR Proteins in Genome Editing and Biotechnology. J Mol Biol 435, 168120. doi:10.1016/j.jmb.2023.168120.
https://www.ncbi.nlm.nih.gov/pubmed/37100169
Kreutzfeld, O., Tumwebaze, P.K., Okitwi, M., Orena, S., Byaruhanga, O., Katairo, T., Conrad, M.D., Rasmussen, S.A., Legac, J., Aydemir, O., et al. (2023). Susceptibility of Ugandan Plasmodium falciparum Isolates to the Antimalarial Drug Pipeline. Microbiol Spectr 11, e0523622. doi:10.1128/spectrum.05236-22. PMCID: PMC10269555
https://www.ncbi.nlm.nih.gov/pubmed/37158739
Kulkarni, A., Ewen-Campen, B., Terao, K., Matsumoto, Y., Li, Y., Watanabe, T., Kao, J.A., Parhad, S.S., Ylla, G., Mizunami, M., and Extavour, C.G. (2023). oskar acts with the transcription factor Creb to regulate long-term memory in crickets. Proc Natl Acad Sci U S A 120, e2218506120. doi:10.1073/pnas.2218506120. PMCID: PMC10214185
https://www.ncbi.nlm.nih.gov/pubmed/37192168
Landshammer, A., Bolondi, A., Kretzmer, H., Much, C., Buschow, R., Rose, A., Wu, H.J., Mackowiak, S.D., Braendl, B., Giesselmann, P., et al. (2023). T-REX17 is a transiently expressed non-coding RNA essential for human endoderm formation. Elife 12. doi:10.7554/eLife.83077. PMCID: PMC9889090
https://www.ncbi.nlm.nih.gov/pubmed/36719724
Lee, L., Yu, H., Jia, B.B., Jussila, A., Zhu, C., Chen, J., Xie, L., Hafner, A., Mishra, S., Wang, D.D., et al. (2023). SnapFISH: a computational pipeline to identify chromatin loops from multiplexed DNA FISH data. Nat Commun 14, 4873. doi:10.1038/s41467-023-40658-3. PMCID: PMC10423204
https://www.ncbi.nlm.nih.gov/pubmed/37573342
Leylek, O., Honeywell, M.E., Lee, M.J., Hemann, M.T., and Ozcan, G. (2023). Functional genomics reveals an off-target dependency of drug synergy in gastric cancer therapy. bioRxiv. doi:10.1101/2023.10.07.561351. PMCID: PMC10592690
https://www.ncbi.nlm.nih.gov/pubmed/37873383
Li, H., Gazzola, D., Hu, Y., and Aroian, R.V. (2023). An efficient method for viable cryopreservation and recovery of hookworms and other gastrointestinal nematodes in the laboratory. Int J Parasitol 53, 451-458. doi:10.1016/j.ijpara.2023.05.001. PMCID: PMC10330584
https://www.ncbi.nlm.nih.gov/pubmed/37201563
Liang, S.Q., Liu, P., Ponnienselvan, K., Suresh, S., Chen, Z., Kramme, C., Chatterjee, P., Zhu, L.J., Sontheimer, E.J., Xue, W., and Wolfe, S.A. (2023). Genome-wide profiling of prime editor off-target sites in vitro and in vivo using PE-tag. Nat Methods 20, 898-907. doi:10.1038/s41592-023-01859-2.
https://www.ncbi.nlm.nih.gov/pubmed/37156841
Liu, H., Caliz, A.D., Learnard, H., Koupenova, M., Keaney, J.F., Kant, S., Zhu, L.J., and Vertii, A. (2023). Inflammatory stress-mediated chromatin changes underlie dysfunction in endothelial cells. bioRxiv. doi:10.1101/2023.10.11.561959. PMCID: PMC10614786
https://www.ncbi.nlm.nih.gov/pubmed/37905100
Luo, S., Lyu, Z., Ge, L., Li, Y., Liu, Y., Yuan, Y., Zhao, R., Huang, L., Zhao, J., Huang, H., and Luo, Y. (2023). Ataxia Telangiectasia Mutated Protects against Lipopolysaccaride-Induced Blood-Brain Barrier Disruption by Regulating Atk/Drp1-Mediated Mitochondrial Homeostasis. Shock 60, 100-109. doi:10.1097/SHK.0000000000002139. PMCID: PMC10417231
https://www.ncbi.nlm.nih.gov/pubmed/37141173
Malvi, P., Chava, S., Cai, G., Hu, K., Zhu, L.J., Edwards, Y.J.K., Green, M.R., Gupta, R., and Wajapeyee, N. (2023). HOXC6 drives a therapeutically targetable pancreatic cancer growth and metastasis pathway by regulating MSK1 and PPP2R2B. Cell Rep Med 4, 101285. doi:10.1016/j.xcrm.2023.101285. PMCID: PMC10694669
https://www.ncbi.nlm.nih.gov/pubmed/37951219
McGee, A.V., Liu, Y.V., Griffith, A.L., Szegletes, Z.M., Wen, B., Kraus, C., Miller, N.W., Steger, R.J., Velasco, B.E., Bosch, J.A., et al. (2023). Modular vector assembly enables rapid assessment of emerging CRISPR technologies. bioRxiv. doi:10.1101/2023.10.25.564061. PMCID: PMC10634825
https://www.ncbi.nlm.nih.gov/pubmed/37961518
Mirza, Z., Walhout, A.J.M., and Ambros, V. (2023). A bacterial pathogen induces developmental slowing by high reactive oxygen species and mitochondrial dysfunction in Caenorhabditis elegans. Cell Rep 42, 113189. doi:10.1016/j.celrep.2023.113189.
https://www.ncbi.nlm.nih.gov/pubmed/37801396
Mou, H., Eskiocak, O., Ozler, K.A., Gorman, M., Yue, J., Jin, Y., Wang, Z., Gao, Y., Janowitz, T., Meyer, H.V., et al. (2023). CRISPR-induced exon skipping of beta-catenin reveals tumorigenic mutants driving distinct subtypes of liver cancer. J Pathol 259, 415-427. doi:10.1002/path.6054. PMCID: PMC10273193
https://www.ncbi.nlm.nih.gov/pubmed/36641763
Nandy, A., Helderman, R.C.M., Thapa, S., Jayapalan, S., Richards, A., Narayani, N., Czech, M.P., Rosen, C.J., and Rendina-Ruedy, E. (2023). Lipolysis supports bone formation by providing osteoblasts with endogenous fatty acid substrates to maintain bioenergetic status. Bone Res 11, 62. doi:10.1038/s41413-023-00297-2. PMCID: PMC10673934
https://www.ncbi.nlm.nih.gov/pubmed/38001111
Odongo, L., Zadrozny, K.K., Diehl, W.E., Luban, J., White, J.M., Ganser-Pornillos, B.K., Tamm, L.K., and Pornillos, O. (2023). Purification and structure of luminal domain C of human Niemann-Pick C1 protein. Acta Crystallogr F Struct Biol Commun 79, 45-50. doi:10.1107/S2053230X23000705. PMCID: PMC9903137
https://www.ncbi.nlm.nih.gov/pubmed/36748341
Osmanski, A.B., Paulat, N.S., Korstian, J., Grimshaw, J.R., Halsey, M., Sullivan, K.A.M., Moreno-Santillan, D.D., Crookshanks, C., Roberts, J., Garcia, C., et al. (2023). Insights into mammalian TE diversity through the curation of 248 genome assemblies. Science 380, eabn1430. doi:10.1126/science.abn1430.
https://www.ncbi.nlm.nih.gov/pubmed/37104570
Park, G., Haley, J.A., Le, J., Jung, S.M., Fitzgibbons, T.P., Korobkina, E.D., Li, H., Fluharty, S.M., Chen, Q., Spinelli, J.B., et al. (2023). Quantitative analysis of metabolic fluxes in brown fat and skeletal muscle during thermogenesis. Nat Metab 5, 1204-1220. doi:10.1038/s42255-023-00825-8. PMCID: PMC10696589
https://www.ncbi.nlm.nih.gov/pubmed/37337122
Park, S.J., Greer, P.L., and Lee, N. (2023). From odor to oncology: non-canonical odorant receptors in cancer. Oncogene. doi:10.1038/s41388-023-02908-y.
https://www.ncbi.nlm.nih.gov/pubmed/38087050
Paschalidis, A., Watson, O.J., Aydemir, O., Verity, R., and Bailey, J.A. (2023). coiaf: Directly estimating complexity of infection with allele frequencies. PLoS Comput Biol 19, e1010247. doi:10.1371/journal.pcbi.1010247. PMCID: PMC10310041
https://www.ncbi.nlm.nih.gov/pubmed/37294835
Paulat, N.S., Storer, J.M., Moreno-Santillan, D.D., Osmanski, A.B., Sullivan, K.A.M., Grimshaw, J.R., Korstian, J., Halsey, M., Garcia, C.J., Crookshanks, C., et al. (2023). Chiropterans Are a Hotspot for Horizontal Transfer of DNA Transposons in Mammalia. Mol Biol Evol 40. doi:10.1093/molbev/msad092. PMCID: PMC10162687
https://www.ncbi.nlm.nih.gov/pubmed/37071810
Ponnienselvan, K., Liu, P., Nyalile, T., Oikemus, S., Maitland, S.A., Lawson, N.D., Luban, J., and Wolfe, S.A. (2023). Reducing the inherent auto-inhibitory interaction within the pegRNA enhances prime editing efficiency. Nucleic Acids Res 51, 6966-6980. doi:10.1093/nar/gkad456. PMCID: PMC10359601
https://www.ncbi.nlm.nih.gov/pubmed/37246708
Rowland, L.A., and Czech, M.P. (2023). Fatty acid availability controls autophagy and associated cell functions. Autophagy 19, 3242-3243. doi:10.1080/15548627.2023.2246357. PMCID: PMC10621277
https://www.ncbi.nlm.nih.gov/pubmed/37602798
Rowland, L.A., Guilherme, A., Henriques, F., DiMarzio, C., Munroe, S., Wetoska, N., Kelly, M., Reddig, K., Hendricks, G., Pan, M., et al. (2023). De novo lipogenesis fuels adipocyte autophagosome and lysosome membrane dynamics. Nat Commun 14, 1362. doi:10.1038/s41467-023-37016-8. PMCID: PMC10011520
https://www.ncbi.nlm.nih.gov/pubmed/36914626
Roy, A., Sakthikumar, S., Kozyrev, S.V., Nordin, J., Pensch, R., Makelainen, S., Pettersson, M., Zoonomia, C., Karlsson, E.K., Lindblad-Toh, K., and Forsberg-Nilsson, K. (2023). Using evolutionary constraint to define novel candidate driver genes in medulloblastoma. Proc Natl Acad Sci U S A 120, e2300984120. doi:10.1073/pnas.2300984120. PMCID: PMC10438395
https://www.ncbi.nlm.nih.gov/pubmed/37549291
Saikumar Lakshmi, P., Oduor, C.I., Forconi, C.S., M'Bana, V., Bly, C., Gerstein, R.M., Otieno, J.A., Ong'echa, J.M., Munz, C., Luftig, M.A., et al. (2023). Endemic Burkitt lymphoma avatar mouse models for exploring inter-patient tumor variation and testing targeted therapies. Life Sci Alliance 6. doi:10.26508/lsa.202101355. PMCID: PMC9990458
https://www.ncbi.nlm.nih.gov/pubmed/36878637
Santos, K., Knobl, P., Henriques, F., Lopes, M.A., Franco, F.O., Bueno, L.L., Farmer, S.R., and Batista, M.L., Jr. (2023). Pathological beige remodeling induced by cancer cachexia depends on the disease severity and involves mainly the trans-differentiation of mature white adipocytes. bioRxiv. doi:10.1101/2023.09.18.558327. PMCID: PMC10541144
https://www.ncbi.nlm.nih.gov/pubmed/37781595
Sayin, S., Rosener, B., Li, C.G., Ho, B., Ponomarova, O., Ward, D.V., Walhout, A.J.M., and Mitchell, A. (2023). Evolved bacterial resistance to the chemotherapy gemcitabine modulates its efficacy in co-cultured cancer cells. Elife 12. doi:10.7554/eLife.83140. PMCID: PMC9931390
https://www.ncbi.nlm.nih.gov/pubmed/36734518
Schmied, C., Nelson, M.S., Avilov, S., Bakker, G.J., Bertocchi, C., Bischof, J., Boehm, U., Brocher, J., Carvalho, M.T., Chiritescu, C., et al. (2023). Community-developed checklists for publishing images and image analyses. Nat Methods. doi:10.1038/s41592-023-01987-9.
https://www.ncbi.nlm.nih.gov/pubmed/37710020
Shah, S., Sharp, K.J., Raju Ponny, S., Lee, J., Watts, J.K., Berry-Kravis, E., and Richter, J.D. (2023). Antisense oligonucleotide rescue of CGG expansion-dependent FMR1 mis-splicing in fragile X syndrome restores FMRP. Proc Natl Acad Sci U S A 120, e2302534120. doi:10.1073/pnas.2302534120. PMCID: PMC10319035
https://www.ncbi.nlm.nih.gov/pubmed/37364131
Shaver, A.O., Wit, J., Dilks, C.M., Crombie, T.A., Li, H., Aroian, R.V., and Andersen, E.C. (2023). Variation in anthelmintic responses are driven by genetic differences among diverse C. elegans wild strains. PLoS Pathog 19, e1011285. doi:10.1371/journal.ppat.1011285. PMCID: PMC10101645
https://www.ncbi.nlm.nih.gov/pubmed/37011090
Shinde, A.B., Nunn, E.R., Wilson, G.A., Chvasta, M.T., Pinette, J.A., Myers, J.W., Peck, S.H., Spinelli, J.B., and Zaganjor, E. (2023). Inhibition of nucleotide biosynthesis disrupts lipid accumulation and adipogenesis. J Biol Chem 299, 104635. doi:10.1016/j.jbc.2023.104635. PMCID: PMC10149209
https://www.ncbi.nlm.nih.gov/pubmed/36963490
Sokolova, V., Lee, G., Mullins, A., Mody, P., Watanabe, S., and Tan, D. (2023). DNA-translocation-independent role of INO80 remodeler in DNA damage repairs. J Biol Chem 299, 105245. doi:10.1016/j.jbc.2023.105245. PMCID: PMC10570696
https://www.ncbi.nlm.nih.gov/pubmed/37696438
Soni, A., Herbert, C., Lin, H., Yan, Y., Pretz, C., Stamegna, P., Wang, B., Orwig, T., Wright, C., Tarrant, S., et al. (2023). Performance of Rapid Antigen Tests to Detect Symptomatic and Asymptomatic SARS-CoV-2 Infection : A Prospective Cohort Study. Ann Intern Med 176, 975-982. doi:10.7326/M23-0385. PMCID: PMC10321467
https://www.ncbi.nlm.nih.gov/pubmed/37399548
Soni, A., Herbert, C., Pretz, C., Stamegna, P., Filippaios, A., Shi, Q., Suvarna, T., Harman, E., Schrader, S., Nowak, C., et al. (2023). Design and implementation of a digital site-less clinical study of serial rapid antigen testing to identify asymptomatic SARS-CoV-2 infection. J Clin Transl Sci 7, e120. doi:10.1017/cts.2023.540. PMCID: PMC10260333
https://www.ncbi.nlm.nih.gov/pubmed/37313378
Soto, E.R., Rus, F., Mirza, Z., and Ostroff, G.R. (2023). Yeast Particles for Encapsulation of Terpenes and Essential Oils. Molecules 28. doi:10.3390/molecules28052273. PMCID: PMC10005402
https://www.ncbi.nlm.nih.gov/pubmed/36903519
Soto, E.R., Specht, C.A., Lee, C.K., Levitz, S.M., and Ostroff, G.R. (2023). One Step Purification-Vaccine Delivery System. Pharmaceutics 15. doi:10.3390/pharmaceutics15051390. PMCID: PMC10223649
https://www.ncbi.nlm.nih.gov/pubmed/37242632
Soto, E.R., Specht, C.A., Rus, F., Lee, C.K., Abraham, A., Levitz, S.M., and Ostroff, G.R. (2023). An efficient (nano) silica - In glucan particles protein encapsulation approach for improved thermal stability. J Control Release 357, 175-184. doi:10.1016/j.jconrel.2023.03.027.
https://www.ncbi.nlm.nih.gov/pubmed/36933700
Sullivan, P.F., Meadows, J.R.S., Gazal, S., Phan, B.N., Li, X., Genereux, D.P., Dong, M.X., Bianchi, M., Andrews, G., Sakthikumar, S., et al. (2023). Leveraging base-pair mammalian constraint to understand genetic variation and human disease. Science 380, eabn2937. doi:10.1126/science.abn2937. PMCID: PMC10259825
https://www.ncbi.nlm.nih.gov/pubmed/37104612
Sun, B., Kim, H., Mello, C.C., and Priess, J.R. (2023). The CERV protein of Cer1, a C. elegans LTR retrotransposon, is required for nuclear export of viral genomic RNA and can form giant nuclear rods. PLoS Genet 19, e1010804. doi:10.1371/journal.pgen.1010804. PMCID: PMC10309623
https://www.ncbi.nlm.nih.gov/pubmed/37384599
Tang, Q., Fakih, H.H., Zain Ui Abideen, M., Hildebrand, S.R., Afshari, K., Gross, K.Y., Sousa, J., Maebius, A.S., Bartholdy, C., Sogaard, P.P., et al. (2023). Rational design of a JAK1-selective siRNA inhibitor for the modulation of autoimmunity in the skin. Nat Commun 14, 7099. doi:10.1038/s41467-023-42714-4. PMCID: PMC10625637
https://www.ncbi.nlm.nih.gov/pubmed/37925520
Tettoni, S.D., Egri, S.B., Doxsey, D.D., Veinotte, K., Ouch, C., Chang, J.Y., Song, K., Xu, C., and Shen, K. (2023). Structure of the Schizosaccharomyces pombe Gtr-Lam complex reveals evolutionary divergence of mTORC1-dependent amino acid sensing. Structure 31, 1065-1076 e1065. doi:10.1016/j.str.2023.06.012. PMCID: PMC10529327
https://www.ncbi.nlm.nih.gov/pubmed/37453417
Tian, Y., Mehta, K., Jellinek, M.J., Sun, H., Lu, W., Shi, R., Ingram, K., Friedline, R.H., Kim, J.K., Kemper, J.K., et al. (2023). Hepatic Phospholipid Remodeling Modulates Insulin Sensitivity and Systemic Metabolism. Adv Sci (Weinh) 10, e2300416. doi:10.1002/advs.202300416. PMCID: PMC10288282
https://www.ncbi.nlm.nih.gov/pubmed/37088778
Tsagkaraki, E., Guilherme, A., Nicoloro, S.M., Kelly, M., Lifshitz, L.M., Wang, H., Min, K., Rowland, L.A., Santos, K.B., Wetoska, N., et al. (2023). Crosstalk between corepressor NRIP1 and cAMP signaling on adipocyte thermogenic programming. Mol Metab 76, 101780. doi:10.1016/j.molmet.2023.101780. PMCID: PMC10410517
https://www.ncbi.nlm.nih.gov/pubmed/37482187
Van't Spijker, H.M., and Almeida, S. (2023). How villains are made: The translation of dipeptide repeat proteins in C9ORF72-ALS/FTD. Gene 858, 147167. doi:10.1016/j.gene.2023.147167. PMCID: PMC9928902
https://www.ncbi.nlm.nih.gov/pubmed/36621656
Wang, M., Wisniewski, C.A., Xiong, C., Chhoy, P., Goel, H.L., Kumar, A., Zhu, L.J., Li, R., St Louis, P.A., Ferreira, L.M., et al. (2023). Therapeutic blocking of VEGF binding to neuropilin-2 diminishes PD-L1 expression to activate antitumor immunity in prostate cancer. Sci Transl Med 15, eade5855. doi:10.1126/scitranslmed.ade5855.
https://www.ncbi.nlm.nih.gov/pubmed/37134151
Wang, R., Oliveira, L.V.N., Lourenco, D., Gomez, C.L., Lee, C.K., Hester, M.M., Mou, Z., Ostroff, G.R., Specht, C.A., and Levitz, S.M. (2023). Immunological correlates of protection following vaccination with glucan particles containing Cryptococcus neoformans chitin deacetylases. NPJ Vaccines 8, 6. doi:10.1038/s41541-023-00606-0. PMCID: PMC9892683
https://www.ncbi.nlm.nih.gov/pubmed/36732332
Wang, Y., Lifshitz, L., Silverstein, N.J., Mintzer, E., Luk, K., StLouis, P., Brehm, M.A., Wolfe, S.A., Deeks, S.G., and Luban, J. (2023). Transcriptional and chromatin profiling of human blood innate lymphoid cell subsets sheds light on HIV-1 pathogenesis. EMBO J 42, e114153. doi:10.15252/embj.2023114153. PMCID: PMC10425848
https://www.ncbi.nlm.nih.gov/pubmed/37382276
Williams, P.D.E., Brewer, M.T., Aroian, R., Robertson, A.P., and Martin, R.J. (2023). The nematode (Ascaris suum) intestine is a location of synergistic anthelmintic effects of Cry5B and levamisole. bioRxiv. doi:10.1101/2023.11.20.567786. PMCID: PMC10690214
https://www.ncbi.nlm.nih.gov/pubmed/38045368
Wilson, I.D., Broeckling, C., Gethings, L.A., Munjoma, N.C., Trengove, R., Rainville, P.D., Lai, S.K., Isaac, G., and Plumb, R.S. (2023). Development of a single mobile phase for LC-IM-MS-based discovery lipidomics and metabolic phenotyping: Application to methapyrilene hepatotoxicity in the rat. J Chromatogr A 1714, 464552. doi:10.1016/j.chroma.2023.464552.
https://www.ncbi.nlm.nih.gov/pubmed/38113579
Xue, G., Yu, H.J., Buffone, C., Huang, S.W., Lee, K., Goh, S.L., Gres, A.T., Guney, M.H., Sarafianos, S.G., Luban, J., et al. (2023). The HIV-1 capsid core is an opportunistic nuclear import receptor. Nat Commun 14, 3782. doi:10.1038/s41467-023-39146-5. PMCID: PMC10290713
https://www.ncbi.nlm.nih.gov/pubmed/37355754
Xue, J.R., Mackay-Smith, A., Mouri, K., Garcia, M.F., Dong, M.X., Akers, J.F., Noble, M., Li, X., Zoonomia, C., Lindblad-Toh, K., et al. (2023). The functional and evolutionary impacts of human-specific deletions in conserved elements. Science 380, eabn2253. doi:10.1126/science.abn2253. PMCID: PMC10202372
https://www.ncbi.nlm.nih.gov/pubmed/37104592
Yamada, K., Hariharan, V.N., Caiazzi, J., Miller, R., Furguson, C., Sapp, E., Fakih, H., Tan, Q., Yamada, N., Furgal, R.C., et al. (2023). Extended Nucleic Acid (exNA): A Novel, Biologically Compatible Backbone that Significantly Enhances Oligonucleotide Efficacy in vivo. bioRxiv. doi:10.1101/2023.05.26.542506. PMCID: PMC10245983
https://www.ncbi.nlm.nih.gov/pubmed/37292886
Yang, J., Jiao, J., Draheim, K.M., Yang, G., Yang, H., Yao, L.C., Shultz, L.D., Greiner, D.L., Rajagopal, D., Vessillier, S., et al. (2023). Simultaneous evaluation of treatment efficacy and toxicity for bispecific T-cell engager therapeutics in a humanized mouse model. FASEB J 37, e22995. doi:10.1096/fj.202300040R. PMCID: PMC10242584
https://www.ncbi.nlm.nih.gov/pubmed/37219526
Yang Loureiro, Z., Joyce, S., DeSouza, T., Solivan-Rivera, J., Desai, A., Skritakis, P., Yang, Q., Ziegler, R., Zhong, D., Nguyen, T.T., et al. (2023). Wnt signaling preserves progenitor cell multipotency during adipose tissue development. Nat Metab 5, 1014-1028. doi:10.1038/s42255-023-00813-y. PMCID: PMC10290956
https://www.ncbi.nlm.nih.gov/pubmed/37337125
Yang, Q., Loureiro, Z.Y., Desai, A., DeSouza, T., Li, K., Wang, H., Nicoloro, S.M., Solivan-Rivera, J., and Corvera, S. (2023). Regulation of lipolysis by 14-3-3 proteins on human adipocyte lipid droplets. PNAS Nexus 2, pgad420. doi:10.1093/pnasnexus/pgad420. PMCID: PMC10733194
https://www.ncbi.nlm.nih.gov/pubmed/38130664
Yenilmez, B., Harney, S., DiMarzio, C., Kelly, M., Min, K., Echeverria, D., Bramato, B.M., Jackson, S.O., Reddig, K., Kim, J.K., et al. (2023). Dual targeting of hepatocyte DGAT2 and stellate cell FASN alleviates nonalcoholic steatohepatitis in mice. bioRxiv. doi:10.1101/2023.07.05.547848. PMCID: PMC10350091
https://www.ncbi.nlm.nih.gov/pubmed/37461560
Yurkovetskiy, L., Egri, S., Kurhade, C., Diaz-Salinas, M.A., Jaimes, J.A., Nyalile, T., Xie, X., Choudhary, M.C., Dauphin, A., Li, J.Z., et al. (2023). S:D614G and S:H655Y are gateway mutations that act epistatically to promote SARS-CoV-2 variant fitness. bioRxiv. doi:10.1101/2023.03.30.535005. PMCID: PMC10081308
https://www.ncbi.nlm.nih.gov/pubmed/37034621
Zhang, H., Kelly, K., Lee, J., Echeverria, D., Cooper, D., Panwala, R., Amrani, N., Chen, Z., Gaston, N., Wagh, A., et al. (2023). Self-delivering, chemically modified CRISPR RNAs for AAV co-delivery and genome editing in vivo. Nucleic Acids Res. doi:10.1093/nar/gkad1125.
https://www.ncbi.nlm.nih.gov/pubmed/38033325
Zhang, H., Kelly, K., Lee, J., Echeverria, D., Cooper, D., Panwala, R., Chen, Z., Gaston, N., Newby, G.A., Xie, J., et al. (2023). Self-delivering CRISPR RNAs for AAV Co-delivery and Genome Editing in vivo. bioRxiv. doi:10.1101/2023.03.20.533459. PMCID: PMC10055305
https://www.ncbi.nlm.nih.gov/pubmed/36993169
Zhu, Y.P., Speir, M., Tan, Z., Lee, J.C., Nowell, C.J., Chen, A.A., Amatullah, H., Salinger, A.J., Huang, C.J., Wu, G., et al. (2023). NET formation is a default epigenetic program controlled by PAD4 in apoptotic neutrophils. Sci Adv 9, eadj1397. doi:10.1126/sciadv.adj1397. PMCID: PMC10732518
https://www.ncbi.nlm.nih.gov/pubmed/38117877