Publications (selected)
Marre, M. L., McGinty, J. W., Chow, I.-T., DeNicola, M. E., Beck, N. W, Kent, S. C., Powers, A. C., Bottino, R., Harlan, D. M., Greenbaum, C. J., Kwok, W. W., Piganelli, J. D., and E. A. James. Modifying enzymes are elicited by ER stress, generating epitopes that are selectively recognized by CD4+ T cells in patients with type 1 diabetes. Diabetes. Online ahead of print. doi: 10.2337/db17-1166 (2018).
Babon, J. A. B., DeNicola, M., Blodgett, D. M., Crèvecoeur, I., Buttrick, T. S., Maehr, R., Bottino, R., Naji, A., Kaddis, J., Elyaman, W., James, E., Haliyur, R., Brissova, M., Overbergh, L., Mathieu, C., Delong, T., Haskins, T., Pugliese, A., Campbell Thompson, M., Mathews, C., Atkinson, M. A., Powers, A. C., Harlan, D. M., and S. C. Kent. Analysis of self-antigen specificity of islet-infiltrating T cells from human donors with type 1 diabetes. Nature Medicine. 22:1482-1487 (2016).
Delong, T., Wiles, T. A., Baker, R. L., Bradley, B., Barbour, G., Reisdorph, R., Armstrong, M., Powell, R. L., Reisdorph, N., Kumar, N., Elso, C. M., DeNicola, M., Bottino, R., Powers, A. C., Harlan, D. H., Kent, S. C., Mannering, S. I., and K. Haskins. Pathogenic CD4 T cells in type 1 diabetes recognize epitopes formed by peptide fusion. Science. 351: 711-714 (2016).
Yeste, A., Mascanfroni, I., Nadeau, M., Kenison, J., Patel, B., Tukpah, A.-M., Babon, J. A. B., DeNicola, M., Kent, S. C., Pozo, D., and F. Quintana. Tolerogenic nanoparticles inhibit T cell-mediated autoimmunity through SOCS2. Science Signaling. 9:ra61 (2016).
Kent, S. C.,* Chen, Y.,* Bregoli, L., Clemmings, S. M., Kenyon, N. S., Ricordi, C., Hering, B. J., and D. A. Hafler. Expanded T cells from pancreatic lymph nodes of type 1 diabetic recognize an insulin epitope. Nature. 435:224-228 (2005). *co-first author
van den Elzen, P., Garg, S., Leon, L., Brigl, M., Leadbetter, E. A., Gumperz, J. E., Dascher, C. C., Cheng, T.-Y., Sacks, F. M., Illarionov, P. A., Besra, G. S., Kent, S. C., Moody, D. B., and M. B. Brenner. Apolipoprotein-mediated pathways of lipid antigen presentation. Nature. 437:906-910 (2005).
Brigl, M., Bry, L., Kent, S. C., Gumperz, J. E. and M. B. Brenner. Mechanism of CD1d-restricted Natural Killer T cell activation during microbial infection. Nature Immunology. 4:1230-1237 (2003).
Viglietta, V., Kent S. C., Orban, T., and D. A. Hafler. GAD65-reactive T cells are activated in patients with autoimmune type 1a diabetes. Journal of Clinical Investigation. 109:895-903 (2002).
Wilson, S. B.*, Kent, S. C.*, Patton, K. T., Orban, T., Jackson, R. A., Exley. M., Porcelli, S., Schatz, D. A., Atkinson, M. A., Balk, S. P., Strominger, J. L. and D. A. Hafler. Extreme Th1 bias of invariant Va24JaQ T cells in Type 1 Diabetes. Nature. 391:177-181 (1998). *co-first authors.
Fukaura, H., Kent, S. C., Pietrusewicz, M. J., Khoury, S. J., Weiner, H. L., and D. A. Hafler. Induction of circulating myelin basic protein and proteolipid protein-specific transforming growth factor-beta1-secreting Th3 T cells by oral administration of myelin in multiple sclerosis patients. Journal of Clinical Investigation. 98:70-77 1996).
A complete list of Dr. Kent's published work can be found in
My Bibliography