Research

Overview

My research focuses on developing both small and bright tools for biomedical applications, that is, designing synthetic/semi-synthetic nanomaterials with unique programmable physical properties for basic science and biomedical applications.  These nanomaterials will be developed using a synergetic multidisciplinary approach, including synthetic chemistry, materials science, biochemistry, and cell biology.  In particular, we are most interested in developing optically active nanomaterials for probing signal transduction pathways, single-molecule imaging, synthesizing functional nanoscale scaffolds for targeted and traceable delivery of small molecules to cells and organelles, as well as for accurately detecting biomarkers in early stage disease.

Research Topics

• Synthesis, modification and application of upconversion nanoparticles (UCNPs) for biomedical applications
• Synthesis, modification and application of persistent luminescence nanoparticles (PLNPs) for biomedical applications
• Synthesis, modification and application of organic dyes for biomedical applications