External Awards for Research Training
Trainees planning applications to NIH or other funding agencies are encouraged to directly contact current and past awardees to request advice and/or copies of the funded applications.
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Characterization of Enterovirus 68 3C Protease For the Development of Robust and Potent Direct-Acting Antiviral Inhibitors
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VEGF/Neuropilin-2 Signaling and Radioresistance in Triple-Negative Breast Cancer
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Identification of a putative mitochondrial solute carrier that regulates mitophagy
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Investigating siRNA-mediated inhibition of ischemia-reperfusion injury during the liver transplantation process
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Examining the Role of a Pathogenic HTT Isoform, HTT1a, in Somatic Expansion and RNA Aggregation in Huntington's Disease
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Modulation of mitochondrial biogenesis by the Integrated Stress Response (ISR)
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Outlining Shadows of Structural Racism Using Publicly Available Social Determinants of Health Data
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Implementation of Medications for Opioid Use Disorder in Massachusetts Jails
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Investigating the Role of cnb-1 and chpf-1 in GABA DD Motor Neuron Remodeling and Synapse Maintenance
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Bacterial targeting of the P-glycoprotein/endocannabinoid axis for reducing intestinal inflammation in ulcerative colitis
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Structure-based Antiviral Design against HTLV-1 Protease
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Investigating the Role of Endosomal Toll-Like Receptors in Remyelination
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Modulation of Somatic Repeat Expansion as a Therapeutic Approach to Huntington's Disease
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Establishing and optimizing a prime editing method in neurons for treatment of Rett syndrome
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Elucidating the role of hepatic mTORC2 as a key regulator of carbohydrate metabolism in non-alcoholic fatty liver disease
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Investigating Trisomy 21 Impact on Human Neural Cell Development and Function Using "Trisomy Silencing" in vitro
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Muscle-Specific CRISPR/Cas9 Exon Skipping for Duchenne Muscular Dystrophy Therapeutics
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Care Integration, Supportive Housing, and Outcomes for Medicaid Accountable Care Organization Enrollees with Behavioral Health Conditions
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Mechanism of cell lethality following loss of gene expression
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The role of Neurexin in serotonin synaptic function and social behavior
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Detection of intestinal pathogens through host surveillance of bacterial toxins
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Discovery of a novel role of VPS13D in Autophagy
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Targeting dormant leukemia-initiating cells in T-cell acute lymphoblastic leukemia
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Adherence to Clinical Practice Guidelines for Screening and Management of Pediatric High Blood Pressure within a Massachusetts Safety-Net Health Care System
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Investigating mechanisms of neurodegeneration
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Mechanism of epigenetic inheritance in a mouse model of acute paternal stress
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Investigating the role of MS4As during Alzheimer's disease
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The Impact of Nucleotide Modification Patterns on Therapeutic Small Interfering RNA Activity in the Central Nervous System
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Characterization of MS4A Chemoreceptive Function
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The Influence of Spatial Proximity to Sterile Syringe Sources and Secondary Syringe Exchange on HCV Risk Among Rural People Who Inject Drugs
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Investigating the Activation Mechanism of SARM1 during Axon Degeneration
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Investigating the impact of trisomy 21 silencing on cardiovascular development and function
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Development of Advanced Oligonucleotides for Glioblastoma Therapeutics
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Investigating sliding clamps and their contribution to genome stability
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Pathogen sensing by nuclear hormone receptors in C. elegans intestinal epithelial cells
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Activation of non-apoptotic cell death by the DNA damage response
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Structure-based design of potent and selective chemically modified oligonucleotide inhibitors for APOBEC3 enzymes
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Investigating the role of B cells in pulmonary fibrosis resulting from STING gain-of-function autoinflammation
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Tissue-specific modulation of Apolipoprotein E in neurodegeneration
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Intersectionality of Sexual Orientation, Gender Expression, and Weight Status on Risk of Disordered Eating Behaviors
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Engineering Synthetic Guide RNAs and Compact Base Editors for Enhanced In Vivo Delivery
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Elucidating the structural and mechanistic features of a thermophilic bacteriophage
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Elucidating premature translation termination in Cystic Fibrosis
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Dissecting ADAM10 function in microglia-mediated synapse elimination
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Investigating how the conserved ZNFX-1 protein regulates epigenetic inheritance and germline immortality in Caenorhabditis elegans
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Integrin Regulation of Mammary Gland Development
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Characterizing effects of sperm- and oocyte-derived epigenetic factors on early embryonic gene expression and offspring metabolic function
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Stability of the folded genome
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Feasibility of Smartwatches for Atrial Fibrillation Detection in Older Adults
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Concurrent trajectories of physical frailty and cognitive impairment among nursing home residents and community-dwelling older adults
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Replication-independent DNA methylation dynamics during post-testicular sperm maturation
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Exploiting RNAi-based silencing of Myc and metabolic vulnerabilities to prevent relapse afer Kras inhibition in lung cancer
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Mechanism of cdk4 diabetes rescue in IRS2 knockout mice
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Investigating YAP1 control of differentiation and metabolism in Hepatoblastoma
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Integrin Function in Breast Cancer Initiation
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Defining the Rules for Designing Fully Chemically Modified siRNAs to Treat Genetically Linked Central Nervous System Disorders
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Smoking Cessation in Persons with Mental Health Conditions: Exploring the Role of Family and Friends
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Microglia-derived neuroactive cytokines governing neural circuit excitatory-inhibitory balance
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Trends, Predictors, and Consequences of Child Undernutrition
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A chemical biology approach to studying the role of SARM1 in a novel neuronal degradative pathway
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Amelioration of Beta-hemoglobinopathies by efficient precise deletion of the +58 BCL11A enhancer using orthogonal Cas9-Cas9 chimeras
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The Role of Extracellular Vesicles in Alcohol-Induced Neuroinflammation
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Ethanol's Effects on Brown Adipose Development and Function
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Gq Receptor Regulation of Striatal Dopamine Transporters
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Fluorescent visualization of complement-dependent pannexin activity in microglia
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Modeling Down Syndrome Neural Phenotypes with Chromosomal Silencing
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Impact of Beclin 1 Loss on Breast Cancer Progression
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Targeting BMP signaling to treat advanced melanoma and suppress therapeutic resistance
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C. elegans as a model for host-microbe-drug interactions
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Investigating the Mechanism and Effect of Disease-Associated Increases in the Huntingtin Long 3'UTR Isoform
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The Role of 3' End Formation in Synaptic Function
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Patient and Social Determinants of Health Trajectories Following Coronary Events
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Examining BMP signaling as a regulator of neural crest identity during melanoma initiation and progression
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The Role of miR-122 in Alcoholic Liver Disease
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Structure-based design of robust cross-genotypic NS3/4A protease inhibitors that avoid resistance
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The Role of Innate IL-17 Responses to Aspergillus fumigatus
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The Impact of IRS2-microtubule interactions in the progression of breast cancer
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Functional Health Predictors of Other Cause Mortality Risk in Prostate Cancer
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Modulation of Nicotine Reward-Associated Behaviors by MicroRNAs
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