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About

Located in Worcester, Massachusetts, the UMass Cancer Center is committed to providing exceptional patient care, conducting cutting-edge research at the highest level, offering excellence in education and training, and serving as an educational resource and advocate for the Central Massachusetts community.
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Patients

Expert Cancer Care in Central Massachusetts

We offer comprehensive cancer care for all childhood and adult cancers, combining state-of-the-art treatments with compassionate support for patients and their families.
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Research
Research

Cutting-Edge Cancer Research

We carry out front-line research in basic, translational, clinical and population-based discovery to find newer, better methods for the prevention, detection, diagnosis, and treatment of cancer.
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Education

World Class Medical and Scientific Education

The UMass Cancer Center is dedicated to training the next generation of cancer researchers, clinicians and physician-scientists.
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Michael Green Memorial
Michael Green Memorial

UMass Chan lost one of its greats when Michael R. Green, MD, PhD, passed away unexpectedly in February 2023. We've established these web pages in his memory so our visitors can take a few minutes, from time to time, to peruse and remember him.

Donate to the The Michael R. Green, MD, PhD, Award in Graduate Research:

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Shaoguang Li, MD, PhD

Professor, Department of Medicine, UMass Chan Medical School

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Shaoguang Li, MD, PhD

Research Focus - Molecular Basis of Leukemogenesis and Myeloproliferative Neoplasms

Understanding the biology of leukemia stem cells (LSCs)
Identification of molecular targets specific for LSCs
Elucidation of signaling pathways critical for the development of myeloproliferative neoplasms (MPNs), with a focus on polycythemia vera (PV) induced by JAK2V617F
Understanding the biology of PV-initiating cells
Characterization of the self-renewal mechanisms of normal hematopoietic stem cells

Chen Y, Shan Y, Lu M, et al. Alox5 blockade eradicates JAK2V617F-induced polycythemia vera in mice. Cancer Res. 2017;77(1):164-174.