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Michael Brehm, PhD

Research Focus - Regulation of Human T Cell Function and Homeostasis

  • Characterization of interactions between human T cells and tumors
  • Control of human T cell function within the tumor micro-environment by checkpoint blockade
  • Establishment of human avatar models to study immuno-oncology
  • Elucidation of cytokine control of human T cell responses

Representative Publication

Jangalwe S, Kapoor VN, Xu J, Girnius X, Kennedy NJ, Edwards YJK, Welsh RM, Davis RJ, Brehm MA(2019) Cutting Edge: Early attrition of memory T cells during inflammation and costimulation blockade is regulated concurrently by proapoptotic proteins Fas and Bim. J Immunol. 202(3):647-651.

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In the News

Getting Results…
  • Convocation 2023: Chancellor Collins celebrates symphony of collaboration at UMass Chan

    Convocation 2023: Chancellor Collins celebrates symphony of collaboration at UMass Chan

    Four faculty members were honored with chancellor’s medals and four others were invested as endowed professors at the Convocation and Investiture ceremony at UMass Chan Medical School.

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  • Convocation events 2023

    UMass Chan celebrates start of new academic year with Convocation week

    The festivities begin on Friday, Sept. 8 with the annual White Coat Ceremony, welcoming the new T.H. Chan School of Medicine students into the medical community.

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  • UMass Medical School joins JDRF Center of Excellence in New England to advance type 1 diabetes research

    UMass Medical School joins JDRF Center of Excellence in New England to advance type 1 diabetes research

    Five UMass Medical School scientists from the UMass Diabetes Center of Excellence are part of the JDRF Center of Excellence in New England that launched Feb. 23. The goal of the is to create a cell replacement therapy that could treat and potentially cure type 1 diabetes.

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