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About

Located in Worcester, Massachusetts, the UMass Cancer Center is committed to providing exceptional patient care, conducting cutting-edge research at the highest level, offering excellence in education and training, and serving as an educational resource and advocate for the Central Massachusetts community.
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Patients

Expert Cancer Care in Central Massachusetts

We offer comprehensive cancer care for all childhood and adult cancers, combining state-of-the-art treatments with compassionate support for patients and their families.
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Research
Research

Cutting-Edge Cancer Research

We carry out front-line research in basic, translational, clinical and population-based discovery to find newer, better methods for the prevention, detection, diagnosis, and treatment of cancer.
Education
Education

World Class Medical and Scientific Education

The UMass Cancer Center is dedicated to training the next generation of cancer researchers, clinicians and physician-scientists.
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Michael Green Memorial
Michael Green Memorial

UMass Chan lost one of its greats when Michael R. Green, MD, PhD, passed away unexpectedly in February 2023. We've established these web pages in his memory so our visitors can take a few minutes, from time to time, to peruse and remember him.

Donate to the The Michael R. Green, MD, PhD, Award in Graduate Research:

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Junhao Mao, PhD

Professor, Department of Molecular, Cell and Cancer Biology, UMass Chan Medical School

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Junhao Mao, PhD

Research Focus - Developmental Signaling Pathways in Cancers

Elucidation of Hippo-YAP signaling in gastrointestinal homeostasis and tumorigenesis
Characterization of molecular and genetic control of intestinal stem cells/progenitors
Mouse modeling of human hamartomatous polyposis syndromes
Development of novel animal models of uveal melanoma
Exploration of TEAD-mediated transcriptional regulation in neuroblastoma

Cotton JL, Li Q, Ma L, et al. YAP/TAZ and Hedgehog coordinate growth and patterning in gastrointestinal mesenchyme. Dev Cell. 2017;43(1):35-47.