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Dohoon Kim, PhD

Research Focus - Cancer Metabolism and Metabolic Toxicity

Identifying the metabolic pathways active in cancer cells, which contain toxic intermediates
Selectively poisoning cancer cells by disrupting enzymes that convert a toxic intermediate to a nontoxic metabolite
Investigating toxic metabolites as causative agents in aging and disease

Carlisle AE, Lee N, Mattew-Onabanjo AN, et al. Selenium detoxification is required for cancer-cell survival. Nat Metab. 2020;2(7):603-611

Getting Results…

In new study, UMass Chan scientists induce toxicity to kill cancer cells

Dohoon Kim, PhD, and colleagues have shown that blocking a specific detoxifying enzyme in lung cancer cells leads to cell death, making it a viable target for drug development.

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UMass Chan BRIDGE Fund invests nearly $2M in 13 faculty projects

The BRIDGE Fund supports critical research milestones for inventions and discoveries that have high potential to change the course of disease and continues to grow, increasing from approximately $1 million per year in 2019 to $3 million in 2024.

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Dohoon Kim receives $2 million Young Investigator Award from Suh Kyungbae Science Foundation

Dohoon Kim, PhD, was named a 2017 Suh Kyungbae Science Foundation Young Investigator Award recipient. The accompanying $2 million, five-year grant will support research into changes in metabolic pathways that support cancer cells.

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