Craig Ceol, PhD
Research Focus - Melanoma Progression and Therapy
- Identifying genes involved in melanoma progression
- Determining the mechanistic basis of oncogenes and tumor suppressors in melanoma initiation
- Defining the intersection of melanocyte stem cell biology and melanoma progression
- Developing novel therapies to complement existing targeted immunotherapies
Representative Publication
Venkatesan AM, Vyas R, Gramann AK, et al. Ligand-activated BMP signaling inhibits cell differentiation and death to promote melanoma. J Clin Invest. 2018;128(1):294-308.
Inventions
Targeting GDF6 and BMP Signaling for Anti-cancer Therapy. UMMS15-21; Patent Pending.
A method of treating a melanoma in a subject, comprising administering to a subject an effective amount of an inhibitor of GDF6/BMP13 activity.
- Technology: Small Molecules
- Applications: Cancer, Myeloma
In the News
Getting Results…
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Zebrafish helpful models to study skin conditions like vitiligo and melanoma, UMass Chan scientist writes
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Craig Ceol receives NIH grant to study melanocyte regeneration
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U.S. Army grant advances UMMS studies targeting key melanoma protein
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