Brian Lewis, PhD
Research Focus - Elucidating Mechanisms of Tumor Initiation and Progression
- Development of novel, genetically engineered mouse models of pancreatic and hepatic tumorigenesis
- Identification of factors required for KRAS-driven pancreatic tumor development and progression
- Interrogation of signal transduction changes following inhibition of key signaling pathways in pancreatic cancer cells
- Identification and characterization of drivers of hepatocellular carcinoma dissemination
Representative Publication
Driscoll DR, Karim SA, Sano M, et al. mTORC2 signaling drives the development and progression of pancreatic cancer. Cancer Res. 2016;76(23):6911-6923.
In the News
Getting Results…
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UMass Chan High School Health Careers Program preps students for med school journey
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UMass Chan delivers fitting tribute to young Worcester scholars
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Communicating science: Brian Lewis discusses overcoming therapeutic resistance in pancreatic cancer
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Immunology and microbiology PhD candidate aims to use her voice in science policy career
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David McManus and Brian Lewis named to endowed chairs
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Brian Lewis recognized at Biomedical Science Careers Program Evening of Hope 2020
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