Publications
Dynamic phosphorylation of Hcm1 promotes fitness in chronic stress
Conti MM, Bail JP, Li R, Zhu LJ, Benanti JA.
bioRxiv. 2024 Sep 19. doi: 10.1101/2024.09.18.613713.
Calcineurin promotes adaptation to chronic stress through two distinct mechanisms
Flynn MJ, Harper NW, Li R, Zhu LJ, Lee MJ, Benanti JA.
Mol Biol Cell. 2024 Oct 1;35(10):ar123. doi: 10.1091/mbc.E24-03-0122. Epub 2024 Jul 31.
bioRxiv preprint
Phosphosite Scanning reveals a complex phosphorylation code underlying CDK-dependent activation of Hcm1
Conti MM, Li R, Narváez Ramos MA, Zhu LJ, Fazzio TG, and Benanti JA.
Nat Commun, 2023 Jan 19;14,310. doi: 10.1038/s41467-023-36035-9.
bioRxiv preprint
Identification of deubiquitinase substrates in Saccharomyces cerevisiae by systematic overexpression
Arsenault HE and Benanti JA.
Methods Mol Biol. 2023;2591:237-253. doi: 10.1007/978-1-0716-2803-4_14.
Repression of essential cell cycle genes increases cellular fitness
Conti MM#, Ghizzoni JM#, Gil-Bona A, Wang W, Costanzo M, Li R, Flynn MJ, Zhu LJ, Myers CL, Boone C, Andrews BJ, Benanti JA.
PLoS Genet. 2022 Aug 29;18(8):e1010349. doi: 10.1371/journal.pgen.1010349.
Cip1 tunes cell cycle arrest duration upon calcineurin activation
Flynn MJ and Benanti JA.
Proc Natl Acad Sci U S A. 2022 Jun 7;119(23):e2202469119. doi: 10.1073/pnas.2202469119. Epub 2022 Jun 2.
Ubc1 turnover contributes to the spindle assembly checkpoint in Saccharomyces cerevisiae
Arsenault HE, Ghizzoni JM, Leech CM, Diers AR, Gesta S, Vishnudas VK, Narain NR, Sarangarajan R, Benanti JA.
G3 (Bethesda). 2021 Sep 29:jkab346. doi: 10.1093/g3journal/jkab346.
The coordinate actions of calcineurin and Hog1 mediate the stress response through multiple nodes of the cell cycle network
Leech CM#, Flynn MJ#, Arsenault HE, Ou J, Liu H, Zhu LJ, Benanti JA.
PLoS Genet. 2020 Apr 28;16(4):e1008600. doi: 10.1371/journal.pgen.1008600.
bioRxiv preprint
An order-to-disorder structural switch activates the FoxM1 transcription factor
Marceau AH, Brison CM, Nerli S, Arsenault HE, McShan AC, Chen E, Lee HW, Benanti JA, Sgourakis NG, Rubin SM.
eLife. 2019 May 28;8. pii:e46131. doi: 10.7554/eLife.46131.
A balance of deubiquitinating enzymes controls cell cycle entry
Mapa CE, Arsenault HE, Conti MM, Poti KE, Benanti JA.
Mol Biol Cell. 2018 Nov 15;29(23):2821-2834. doi/10.1091/mbc.E18-07-0425. Epub 2018 Sep 12.
Levels of Ycg1 limit condensin function during the cell cycle
Doughty TW, Arsenault HE, Benanti JA.
PLoS Genet. 2016 Jul 27;12(7):e1006216. doi:10.1371/journal.pgen.1006216. eCollection 2016 Jul.
Create, activate, destroy, repeat: Cdk1 controls proliferation by limiting transcription factor activity
Benanti JA.
Curr Genet. 2016 May;62(2):271-6. doi:10.1007/s00294-015-0535-5. Epub 2015 Nov 21.
Hcm1 integrates signals from Cdk1 and calcineurin to control cell proliferation
Arsenault HE#, Roy J#, Mapa CE, Cyert MS, Benanti JA.
Mol Biol Cell. 2015 Oct 15;26(20):3570-7. doi: 10.1091/mbc.E15-07-0469. Epub 2015 Aug 12.
Regulation of a transcription factor network by Cdk1 coordinates late cell cycle gene expression
Landry BD, Mapa CE, Arsenault HE, Poti KE, Benanti JA.
EMBO J. 2014 May 2;33(9):1044-60. doi: 10.1002/embj.201386877. Epub 2014 Apr 8.
Rad53 downregulates mitotic gene transcription by inhibiting the transcriptional activator Ndd1
Edenberg ER, Vashisht A, Benanti JA, Wohlschlegel J, Toczyski DP.
Mol Cell Biol. 2014 Feb;34(4):725-38. doi: 10.1128/MCB.01056-13. Epub 2013 Dec 9.
F-box protein specificity for G1 cyclins is dictated by subcellular localization
Landry BD, Doyle JP, Toczyski DP, Benanti JA.
PLoS Genet. 2012 8(7):e1002851. doi: 10.1371/journal.pgen.1002851. Epub 2012 Jul 26.
Coordination of cell growth and division by the ubiquitin-proteasome system
Benanti JA.
Semin Cell Dev Biol. 2012 Jul;23(5):492-8. doi:10.1016/j.semcdb.2012.04.005. Epub 2012 Apr 19.
Functionally distinct isoforms of Cik1 are differentially regulated by APC/C-mediated proteolysis
Benanti JA, Matyskiela ME, Morgan DO, Toczyski DP.
Mol Cell. 2009 Mar 13;33(5):581-90. doi: 10.1016/j.molcel.2009.01.032.
Cdc20, an activator at last
Benanti JA, Toczyski DP.
Mol Cell. 2008 Nov21;32(4):460-1. doi: 10.1016/j.molcel.2008.11.006.
Epigenetic down-regulation of ARF expression is a selection step in immortalization of human fibroblasts by c-Myc
Benanti JA#, Wang ML#, Myers HE, Robinson KL, Grandori C, Galloway DA.
Mol Cancer Res. 2007 Nov;5(11):1181-9. Epub 2007 Nov 2. Epub 2007 Nov 2.
A proteomic screen reveals SCFGrr1 targets that regulate the glycolytic-gluconeogenic switch
Benanti JA, Cheung SK, Brady MC, Toczyski DP.
Nat Cell Biol. 2007 Oct;9(10):1184-91. Epub 2007 Sep 9.
Sensitivity of yeast strains with long G-tails to levels of telomere-bound telomerase
Vega LR, Phillips JA, Thornton BR, Benanti JA, Onigbanjo MT, Toczyski DP, Zakian VA.
PLoS Genet. 2007 Jun;3(6):e105.
The normal response to RAS: senescence or transformation?
Benanti JA, Galloway DA.
Cell Cycle. 2004 Jun;3(6):715-7. Epub 2004 Jun 28.
Normal human fibroblasts are resistant to RAS-induced senescence
Benanti JA, Galloway DA.
Mol Cell Biol. 2004 Apr;24(7):2842-52.
Induction of extracellular matrix-remodeling genes by the senescence-associated protein APA-1
Benanti JA, Williams DK, Robinson KL, Ozer HL, Galloway DA.
Mol Cell Biol. 2002 Nov;22(21):7385-97.
The G(2)checkpoint is maintained by redundant pathways
Passalaris TM, Benanti JA, Gewin L, Kiyono T, Galloway DA.
Mol Cell Biol. 1999 Sep;19(9):5872-81.
#equal contributions
